Daniel C Whitehead

TitleAssistant Professor
InstitutionClemson University
DepartmentDepartment of Chemistry
Address223 Hunter Hall
Clemson, South Carolina 29634
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Miller BA, Narangoda CJ, Johnson TL, Barata RD, Belue F, Solomon EE, Bragg AA, Whitehead DC. Telescoped Oxidation and Cycloaddition of Urazoles to Access Diazacyclobutenes. J Org Chem. 2022 06 03; 87(11):7494-7500. PMID: 35549283.
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    2. Rees KC, Dou Z, Whitehead DC. Oxadiazon Derivatives Elicit Potent Intracellular Growth Inhibition against Toxoplasma gondii by Disrupting Heme Biosynthesis. ACS Infect Dis. 2022 05 13; 8(5):911-917. PMID: 35363476.
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    3. Negrete-Bolagay D, Zamora-Ledezma C, Chuya-Sumba C, De Sousa FB, Whitehead D, Alexis F, Guerrero VH. Persistent organic pollutants: The trade-off between potential risks and sustainable remediation methods. J Environ Manage. 2021 Dec 15; 300:113737. PMID: 34536739.
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    4. Brummel BR, Narangoda CJ, Attia MF, Swasy MI, Smith GD, Alexis F, Whitehead DC. Scaled Synthesis of Polyamine-Modified Cellulose Nanocrystals from Bulk Cotton and Their Use for Capturing Volatile Organic Compounds. Polymers (Basel). 2021 Sep 10; 13(18). PMID: 34577961.
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    5. Chingo Aimacaña CM, Pila KO, Quinchiguango Perez DA, Debut A, Attia MF, Santos-Oliveira R, Whitehead DC, Reinoso C, Alexis F, Dahoumane SA. Bimodal Ultrasound and X-ray Bioimaging Properties of Particulate Calcium Fluoride Biomaterial. Molecules. 2021 Sep 07; 26(18). PMID: 34576919.
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    6. Attia MF, Montaser AS, Arifuzzaman M, Pitz M, Jlassi K, Alexander-Bryant A, Kelly SS, Alexis F, Whitehead DC. In Situ Photopolymerization of Acrylamide Hydrogel to Coat Cellulose Acetate Nanofibers for Drug Delivery System. Polymers (Basel). 2021 Jun 03; 13(11). PMID: 34205186.
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    7. Chingo Aimacaña CM, Quinchiguango Perez DA, Rocha Pinto S, Debut A, Attia MF, Santos-Oliveira R, Whitehead DC, Terencio T, Alexis F, Dahoumane SA. Polytetrafluoroethylene-like Nanoparticles as a Promising Contrast Agent for Dual Modal Ultrasound and X-ray Bioimaging. ACS Biomater Sci Eng. 2021 03 08; 7(3):1181-1191. PMID: 33590748.
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    8. Guambo MPR, Spencer L, Vispo NS, Vizuete K, Debut A, Whitehead DC, Santos-Oliveira R, Alexis F. Natural Cellulose Fibers for Surgical Suture Applications. Polymers (Basel). 2020 Dec 18; 12(12). PMID: 33353190.
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    9. Swasy MI, Brummel BR, Narangoda C, Attia MF, Hawk JM, Alexis F, Whitehead DC. Degradation of pesticides using amine-functionalized cellulose nanocrystals. RSC Adv. 2020 Dec 09; 10(72):44312-44322. PMID: 35517180.
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    10. Attia MF, Akasov R, Alexis F, Whitehead DC. Polymer-Scaffolded Synthesis of Periodic Mesoporous Organosilica Nanomaterials for Delivery Systems in Cancer Cells. ACS Biomater Sci Eng. 2020 12 14; 6(12):6671-6679. PMID: 33320612.
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    11. Attia MF, Swasy MI, Akasov R, Alexis F, Whitehead DC. Strategies for High Grafting Efficiency of Functional Ligands to Lipid Nanoemulsions for RGD-Mediated Targeting of Tumor Cells In Vitro. ACS Appl Bio Mater. 2020 Aug 17; 3(8):5067-5079. PMID: 35021683.
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    12. Viera-Herrera C, Santamaría-Aguirre J, Vizuete K, Debut A, Whitehead DC, Alexis F. Microcrystalline Cellulose Extracted from Native Plants as an Excipient for Solid Dosage Formulations in Drug Delivery. Nanomaterials (Basel). 2020 May 19; 10(5). PMID: 32438544.
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    13. Bergmann A, Floyd K, Key M, Dameron C, Rees KC, Thornton LB, Whitehead DC, Hamza I, Dou Z. Toxoplasma gondii requires its plant-like heme biosynthesis pathway for infection. PLoS Pathog. 2020 05; 16(5):e1008499. PMID: 32407406.
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    14. Attia MF, Ranasinghe M, Akasov R, Anker JN, Whitehead DC, Alexis F. In situ preparation of gold-polyester nanoparticles for biomedical imaging. Biomater Sci. 2020 Jun 07; 8(11):3032-3043. PMID: 32314777.
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    15. Yousefi R, Sarkar A, Ashtekar KD, Whitehead DC, Kakeshpour T, Holmes D, Reed P, Jackson JE, Borhan B. Mechanistic Insights into the Origin of Stereoselectivity in an Asymmetric Chlorolactonization Catalyzed by (DHQD)2PHAL. J Am Chem Soc. 2020 04 15; 142(15):7179-7189. PMID: 32202109.
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    16. Bravo I, Figueroa F, Swasy MI, Attia MF, Ateia M, Encalada D, Vizuete K, Galeas S, Guerrero VH, Debut A, Whitehead DC, Alexis F. Cellulose particles capture aldehyde VOC pollutants. RSC Adv. 2020 Feb 18; 10(13):7967-7975. PMID: 35492153.
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    17. Lex TR, Brummel BR, Attia MF, Giambalvo LN, Lee KG, Van Horn BA, Whitehead DC, Alexis F. Iodinated Polyesters with Enhanced X-ray Contrast Properties for Biomedical Imaging. Sci Rep. 2020 01 30; 10(1):1508. PMID: 32001741.
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    18. Attia MF, Swasy MI, Ateia M, Alexis F, Whitehead DC. Periodic mesoporous organosilica nanomaterials for rapid capture of VOCs. Chem Commun (Camb). 2020 Jan 14; 56(4):607-610. PMID: 31830163.
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    19. Brummel BR, Lee KG, McMillen CD, Kolis JW, Whitehead DC. One-Pot Absolute Stereochemical Identification of Alcohols via Guanidinium Sulfate Crystallization. Org Lett. 2019 12 06; 21(23):9622-9627. PMID: 31762284.
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    20. Narangoda CJ, Kakeshpour T, Lex TR, Redden BK, Moore MA, Frank EM, McMillen CD, Wiskur SL, Kitaygorodskiy A, Jackson JE, Whitehead DC. Cycloaddition/Electrocyclic Ring Opening Sequence between Alkynyl Sulfides and Azodicarboxylates To Provide N,N-Dicarbamoyl 2-Iminothioimidates. J Org Chem. 2019 08 02; 84(15):9734-9743. PMID: 31295401.
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    21. Santilli AD, Russell JT, Triplett EW, Whitehead KJ, Whitehead DC. Non-lethal growth inhibition by arresting the starch utilization system of clinically relevant human isolates of Bacteroides dorei. Medchemcomm. 2019 Nov 01; 10(11):1875-1880. PMID: 32280435.
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    22. Narangoda CJ, Lex TR, Moore MA, McMillen CD, Kitaygorodskiy A, Jackson JE, Whitehead DC. Accessing the Rare Diazacyclobutene Motif. Org Lett. 2018 12 21; 20(24):8009-8013. PMID: 30525696.
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    23. Attia MF, Brummel BR, Lex TR, Van Horn BA, Whitehead DC, Alexis F. Recent Advances in Polyesters for Biomedical Imaging. Adv Healthc Mater. 2018 11; 7(22):e1800798. PMID: 30295005.
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    24. Swasy MI, Campbell ML, Brummel BR, Guerra FD, Attia MF, Smith GD, Alexis F, Whitehead DC. Poly(amine) modified kaolinite clay for VOC capture. Chemosphere. 2018 Dec; 213:19-24. PMID: 30205272.
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    25. Santilli AD, Dawson EM, Whitehead KJ, Whitehead DC. Nonmicrobicidal Small Molecule Inhibition of Polysaccharide Metabolism in Human Gut Microbes: A Potential Therapeutic Avenue. ACS Chem Biol. 2018 05 18; 13(5):1165-1172. PMID: 29660284.
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    26. Gordhan HM, Milanes JE, Qiu Y, Golden JE, Christensen KA, Morris JC, Whitehead DC. A targeted delivery strategy for the development of potent trypanocides. Chem Commun (Camb). 2017 Aug 11; 53(62):8735-8738. PMID: 28726862.
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    27. Gordhan HM, Patrick SL, Swasy MI, Hackler AL, Anayee M, Golden JE, Morris JC, Whitehead DC. Evaluation of substituted ebselen derivatives as potential trypanocidal agents. Bioorg Med Chem Lett. 2017 02 01; 27(3):537-541. PMID: 28043795.
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    28. Lex TR, Swasy MI, Whitehead DC. Relative Rate Profiles of Functionalized Iodoarene Catalysts for Iodine(III) Oxidations. J Org Chem. 2015 Dec 18; 80(24):12234-43. PMID: 26599392.
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    29. Campbell ML, Guerra FD, Dhulekar J, Alexis F, Whitehead DC. Target-Specific Capture of Environmentally Relevant Gaseous Aldehydes and Carboxylic Acids with Functional Nanoparticles. Chemistry. 2015 Oct 12; 21(42):14834-42. PMID: 26331393.
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    30. Olsen TR, Davis LL, Nicolau SE, Duncan CC, Whitehead DC, Van Horn BA, Alexis F. Non-invasive deep tissue imaging of iodine modified poly(caprolactone-co-1-4-oxepan-1,5-dione) using X-ray. Acta Biomater. 2015 Jul; 20:94-103. PMID: 25818945.
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    31. Garrido C, Simpson CA, Dahl NP, Bresee J, Whitehead DC, Lindsey EA, Harris TL, Smith CA, Carter CJ, Feldheim DL, Melander C, Margolis DM. Gold nanoparticles to improve HIV drug delivery. Future Med Chem. 2015; 7(9):1097-107. PMID: 26132521.
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    32. Joice AC, Harris MT, Kahney EW, Dodson HC, Maselli AG, Whitehead DC, Morris JC. Exploring the mode of action of ebselen in Trypanosoma brucei hexokinase inhibition. Int J Parasitol Drugs Drug Resist. 2013 Dec; 3:154-60. PMID: 24533305.
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    33. Garzan A, Jaganathan A, Salehi Marzijarani N, Yousefi R, Whitehead DC, Jackson JE, Borhan B. Solvent-dependent enantiodivergence in the chlorocyclization of unsaturated carbamates. Chemistry. 2013 Jul 01; 19(27):9015-21. PMID: 23671005.
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    34. Hart SR, Whitehead DC, Travis BR, Borhan B. Catalytic oxidative cleavage of olefins promoted by osmium tetroxide and hydrogen peroxide. Org Biomol Chem. 2011 Jul 07; 9(13):4741-4. PMID: 21603726.
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    35. Jaganathan A, Garzan A, Whitehead DC, Staples RJ, Borhan B. A catalytic asymmetric chlorocyclization of unsaturated amides. Angew Chem Int Ed Engl. 2011 Mar 07; 50(11):2593-6. PMID: 21370344.
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    36. Yousefi R, Whitehead DC, Mueller JM, Staples RJ, Borhan B. On the chlorenium source in the asymmetric chlorolactonization reaction. Org Lett. 2011 Feb 18; 13(4):608-11. PMID: 21244044.
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    37. Rogers SA, Lindsey EA, Whitehead DC, Mullikin T, Melander C. Synthesis and biological evaluation of 2-aminoimidazole/carbamate hybrid anti-biofilm and anti-microbial agents. Bioorg Med Chem Lett. 2011 Feb 15; 21(4):1257-60. PMID: 21251823.
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    38. Rogers SA, Whitehead DC, Mullikin T, Melander C. Synthesis and bacterial biofilm inhibition studies of ethyl N-(2-phenethyl) carbamate derivatives. Org Biomol Chem. 2010 Sep 07; 8(17):3857-9. PMID: 20617245.
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    39. Whitehead DC, Yousefi R, Jaganathan A, Borhan B. An organocatalytic asymmetric chlorolactonization. J Am Chem Soc. 2010 Mar 17; 132(10):3298-300. PMID: 20170118.
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    40. Schaefer L, Auchtung TA, Hermans KE, Whitehead D, Borhan B, Britton RA. The antimicrobial compound reuterin (3-hydroxypropionaldehyde) induces oxidative stress via interaction with thiol groups. Microbiology (Reading). 2010 Jun; 156(Pt 6):1589-1599. PMID: 20150236.
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    41. Whitehead DC, Staples RJ, Borhan B. A simple and expedient method for the preparation of N-chlorohydantoins. Tetrahedron Lett. 2009 Feb 11; 50(6):656-658. PMID: 20157342.
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    42. Orr RK, Hoehn JL, Col NF. The learning curve for sentinel node biopsy in breast cancer: practical considerations. Arch Surg. 1999 Jul; 134(7):764-7. PMID: 24025085.
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    43. Orr RK, Hoehn JL, Col NF. The learning curve for sentinel node biopsy in breast cancer: practical considerations. Arch Surg. 1999 Jul; 134(7):764-7. PMID: 30021974.
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