Hong Yu

Title
InstitutionMedical University of South Carolina
DepartmentOral Health Sciences
AddressP.O. Box MSC 507
230-A
173 Ashley Ave.
Phone843-792-0635
Fax843-792-6626
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Chung H, Merakou C, Schaefers MM, Flett KB, Martini S, Lu R, Blumenthal JA, Webster SS, Cross AR, Al Ahmar R, Halpin E, Anderson M, Moore NS, Snesrud EC, Yu HD, Goldberg JB, O'Toole GA, McGann P, Stam JA, Hinkle M, McAdam AJ, Kishony R, Priebe GP. Rapid expansion and extinction of antibiotic resistance mutations during treatment of acute bacterial respiratory infections. Nat Commun. 2022 03 09; 13(1):1231. PMID: 35264582.
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    2. Al Ahmar R, Kirby BD, Yu HD. Culture of Small Colony Variant of Pseudomonas aeruginosa and Quantitation of its Alginate. J Vis Exp. 2020 02 22; (156). PMID: 32150164.
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    3. Valentine ME, Kirby BD, Yu HD. Generation of In-Frame Gene Deletion Mutants in Pseudomonas aeruginosa and Testing for Virulence Attenuation in a Simple Mouse Model of Infection. J Vis Exp. 2020 01 08; (155). PMID: 31984966.
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    4. Kirby BD, Al Ahmar R, Withers TR, Valentine ME, Valentovic M, Long TE, Gaskins JR, Yu HD. Efficacy of Aerosolized Rifaximin versus Tobramycin for Treatment of Pseudomonas aeruginosa Pneumonia in Mice. Antimicrob Agents Chemother. 2019 07; 63(7). PMID: 31010865.
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    5. Panmanee W, Su S, Schurr MJ, Lau GW, Zhu X, Ren Z, McDaniel CT, Lu LJ, Ohman DE, Muruve DA, Panos RJ, Yu HD, Thompson TB, Tseng BS, Hassett DJ. The anti-sigma factor MucA of Pseudomonas aeruginosa: Dramatic differences of a mucA22 vs. a ?mucA mutant in anaerobic acidified nitrite sensitivity of planktonic and biofilm bacteria in vitro and during chronic murine lung infection. PLoS One. 2019; 14(6):e0216401. PMID: 31158231.
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    6. Valentine ME, Kirby BD, Withers TR, Johnson SL, Long TE, Hao Y, Lam JS, Niles RM, Yu HD. Generation of a highly attenuated strain of Pseudomonas aeruginosa for commercial production of alginate. Microb Biotechnol. 2020 01; 13(1):162-175. PMID: 31006977.
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    7. Yu H. Sphingosine-1-Phosphate Receptor 2 Regulates Proinflammatory Cytokine Production and Osteoclastogenesis. PLoS One. 2016; 11(5):e0156303. PMID: 27224249.
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    8. Alexander-Bryant AA, Dumitriu A, Attaway CC, Yu H, Jakymiw A. Fusogenic-oligoarginine peptide-mediated silencing of the CIP2A oncogene suppresses oral cancer tumor growth in vivo. J Control Release. 2015 Nov 28; 218:72-81. PMID: 26386438.
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    9. Yu H, Herbert BA, Valerio M, Yarborough L, Hsu LC, Argraves KM. FTY720 inhibited proinflammatory cytokine release and osteoclastogenesis induced by Aggregatibacter actinomycetemcomitans. Lipids Health Dis. 2015 Jul 04; 14:66. PMID: 26138336.
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    10. Yu H, Sun C, Argraves KM. Periodontal inflammation and alveolar bone loss induced by Aggregatibacter actinomycetemcomitans is attenuated in sphingosine kinase 1-deficient mice. J Periodontal Res. 2016 Feb; 51(1):38-49. PMID: 25900155.
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    11. Li Y, Lu Z, Zhang X, Yu H, Kirkwood KL, Lopes-Virella MF, Huang Y. Metabolic syndrome exacerbates inflammation and bone loss in periodontitis. J Dent Res. 2015 Feb; 94(2):362-70. PMID: 25503900.
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    12. Zhang X, Hyer JM, Yu H, D'Silva NJ, Kirkwood KL. DUSP1 phosphatase regulates the proinflammatory milieu in head and neck squamous cell carcinoma. Cancer Res. 2014 Dec 15; 74(24):7191-7. PMID: 25312268.
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    13. Valerio MS, Herbert BA, Basilakos DS, Browne C, Yu H, Kirkwood KL. Critical role of MKP-1 in lipopolysaccharide-induced osteoclast formation through CXCL1 and CXCL2. Cytokine. 2015 Jan; 71(1):71-80. PMID: 25261746.
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    14. Talwar S, House R, Sundaramurthy S, Balasubramanian S, Yu H, Palanisamy V. Inhibition of caspases protects mice from radiation-induced oral mucositis and abolishes the cleavage of RNA-binding protein HuR. J Biol Chem. 2014 Feb 07; 289(6):3487-500. PMID: 24362034.
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    15. Jin J, Machado ER, Yu H, Zhang X, Lu Z, Li Y, Lopes-Virella MF, Kirkwood KL, Huang Y. Simvastatin inhibits LPS-induced alveolar bone loss during metabolic syndrome. J Dent Res. 2014 Mar; 93(3):294-9. PMID: 24352501.
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    16. Yin Y, Withers TR, Wang X, Yu HD. Evidence for sigma factor competition in the regulation of alginate production by Pseudomonas aeruginosa. PLoS One. 2013; 8(8):e72329. PMID: 23991093.
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    17. Yin Y, Wang Y, Zhu L, Liu W, Liao N, Jiang M, Zhu B, Yu HD, Xiang C, Wang X. Comparative analysis of the distribution of segmented filamentous bacteria in humans, mice and chickens. ISME J. 2013 Mar; 7(3):615-21. PMID: 23151642.
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    18. Yu H, Valerio M, Bielawski J. Fenretinide inhibited de novo ceramide synthesis and proinflammatory cytokines induced by Aggregatibacter actinomycetemcomitans. J Lipid Res. 2013 Jan; 54(1):189-201. PMID: 23139430.
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    19. Dunmyer J, Herbert B, Li Q, Zinna R, Martin K, Yu H, Kirkwood KL. Sustained mitogen-activated protein kinase activation with Aggregatibacter actinomycetemcomitans causes inflammatory bone loss. Mol Oral Microbiol. 2012 Oct; 27(5):397-407. PMID: 22958388.
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    20. McAbee J, Li Q, Yu H, Kirkwood KL. Sexual dimorphism in periapical inflammation and bone loss from mitogen-activated protein kinase phosphatase-1 deficient mice. J Endod. 2012 Aug; 38(8):1097-100. PMID: 22794213.
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    21. Ge C, Yang Q, Zhao G, Yu H, Kirkwood KL, Franceschi RT. Interactions between extracellular signal-regulated kinase 1/2 and p38 MAP kinase pathways in the control of RUNX2 phosphorylation and transcriptional activity. J Bone Miner Res. 2012 Mar; 27(3):538-51. PMID: 22072425.
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    22. Yu H, Sun Y, Haycraft C, Palanisamy V, Kirkwood KL. MKP-1 regulates cytokine mRNA stability through selectively modulation subcellular translocation of AUF1. Cytokine. 2011 Nov; 56(2):245-55. PMID: 21733716.
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    23. Trombetta-Esilva J, Yu H, Arias DN, Rossa C, Kirkwood KL, Bradshaw AD. LPS induces greater bone and PDL loss in SPARC-null mice. J Dent Res. 2011 Apr; 90(4):477-82. PMID: 21191126.
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    24. Li Q, Yu H, Zinna R, Martin K, Herbert B, Liu A, Rossa C, Kirkwood KL. Silencing mitogen-activated protein kinase-activated protein kinase-2 arrests inflammatory bone loss. J Pharmacol Exp Ther. 2011 Mar; 336(3):633-42. PMID: 21139061.
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    25. Yu H, Li Q, Herbert B, Zinna R, Martin K, Junior CR, Kirkwood KL. Anti-inflammatory effect of MAPK phosphatase-1 local gene transfer in inflammatory bone loss. Gene Ther. 2011 Apr; 18(4):344-53. PMID: 21068780.
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    26. Buff SM, Yu H, McCall JN, Caldwell SM, Ferkol TW, Flotte TR, Virella-Lowell IL. IL-10 delivery by AAV5 vector attenuates inflammation in mice with Pseudomonas pneumonia. Gene Ther. 2010 May; 17(5):567-76. PMID: 20357828.
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    27. Yu H, Zeidan YH, Wu BX, Jenkins RW, Flotte TR, Hannun YA, Virella-Lowell I. Defective acid sphingomyelinase pathway with Pseudomonas aeruginosa infection in cystic fibrosis. Am J Respir Cell Mol Biol. 2009 Sep; 41(3):367-75. PMID: 19168701.
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    28. Yu H, Buff SM, Baatz JE, Virella-Lowell I. Oral instillation with surfactant phospholipid: a reliable alternative to intratracheal injection in mouse studies. Lab Anim. 2008 Jul; 42(3):294-304. PMID: 18625584.
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    29. Woraratanadharm J, Rubinchik S, Yu H, Dong JY. Novel system uses probasin-based promoter, transcriptional silencers and amplification loop to induce high-level prostate expression. BMC Biotechnol. 2007 Feb 12; 7:9. PMID: 17295927.
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    30. Wang D, Hevey M, Juompan LY, Trubey CM, Raja NU, Deitz SB, Woraratanadharm J, Luo M, Yu H, Swain BM, Moore KM, Dong JY. Complex adenovirus-vectored vaccine protects guinea pigs from three strains of Marburg virus challenges. Virology. 2006 Sep 30; 353(2):324-32. PMID: 16820184.
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    31. Wang D, Raja NU, Trubey CM, Juompan LY, Luo M, Woraratanadharm J, Deitz SB, Yu H, Swain BM, Moore KM, Pratt WD, Hart MK, Dong JY. Development of a cAdVax-based bivalent ebola virus vaccine that induces immune responses against both the Sudan and Zaire species of Ebola virus. J Virol. 2006 Mar; 80(6):2738-46. PMID: 16501083.
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    32. Wang D, Schmaljohn AL, Raja NU, Trubey CM, Juompan LY, Luo M, Deitz SB, Yu H, Woraratanadharm J, Holman DH, Moore KM, Swain BM, Pratt WD, Dong JY. De novo syntheses of Marburg virus antigens from adenovirus vectors induce potent humoral and cellular immune responses. Vaccine. 2006 Apr 05; 24(15):2975-86. PMID: 16530297.
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    33. Chen J, Batta A, Zheng S, Fitzgibbon WR, Ullian ME, Yu H, Tso P, Salen G, Patel SB. The missense mutation in Abcg5 gene in spontaneously hypertensive rats (SHR) segregates with phytosterolemia but not hypertension. BMC Genet. 2005 Jul 18; 6:40. PMID: 16026620.
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    34. Yu H, Wessels A, Tint GS, Patel SB. Partial rescue of neonatal lethality of Dhcr7 null mice by a nestin promoter-driven DHCR7 transgene expression. Brain Res Dev Brain Res. 2005 Apr 21; 156(1):46-60. PMID: 15862627.
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    35. Rubinchik S, Woraratanadharm J, Yu H, Dong JY. New complex Ad vectors incorporating both rtTA and tTS deliver tightly regulated transgene expression both in vitro and in vivo. Gene Ther. 2005 Mar; 12(6):504-11. PMID: 15660114.
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    36. Woraratanadharm J, Rubinchik S, Yu H, Fan F, Morrow SM, Dong JY. Highly specific transgene expression mediated by a complex adenovirus vector incorporating a prostate-specific amplification feedback loop. Gene Ther. 2004 Sep; 11(18):1399-407. PMID: 15229631.
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    37. Klett EL, Lu K, Kosters A, Vink E, Lee MH, Altenburg M, Shefer S, Batta AK, Yu H, Chen J, Klein R, Looije N, Oude-Elferink R, Groen AK, Maeda N, Salen G, Patel SB. A mouse model of sitosterolemia: absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterol. BMC Med. 2004 Mar 24; 2:5. PMID: 15040800.
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    38. Yu H, Wessels A, Chen J, Phelps AL, Oatis J, Tint GS, Patel SB. Late gestational lung hypoplasia in a mouse model of the Smith-Lemli-Opitz syndrome. BMC Dev Biol. 2004 Feb 02; 4:1. PMID: 15005800.
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    39. Rubinchik S, Yu H, Woraratanadharm J, Voelkel-Johnson C, Norris JS, Dong JY. Enhanced apoptosis of glioma cell lines is achieved by co-delivering FasL-GFP and TRAIL with a complex Ad5 vector. Cancer Gene Ther. 2003 Nov; 10(11):814-22. PMID: 14605667.
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    40. Yu H, Pandit B, Klett E, Lee MH, Lu K, Helou K, Ikeda I, Egashira N, Sato M, Klein R, Batta A, Salen G, Patel SB. The rat STSL locus: characterization, chromosomal assignment, and genetic variations in sitosterolemic hypertensive rats. BMC Cardiovasc Disord. 2003 Jun 03; 3:4. PMID: 12783625.
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    41. Lu K, Lee MH, Yu H, Zhou Y, Sandell SA, Salen G, Patel SB. Molecular cloning, genomic organization, genetic variations, and characterization of murine sterolin genes Abcg5 and Abcg8. J Lipid Res. 2002 Apr; 43(4):565-78. PMID: 11907139.
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    42. Rubinchik S, Wang D, Yu H, Fan F, Luo M, Norris JS, Dong JY. A complex adenovirus vector that delivers FASL-GFP with combined prostate-specific and tetracycline-regulated expression. Mol Ther. 2001 Nov; 4(5):416-26. PMID: 11708878.
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    43. Lee MH, Lu K, Hazard S, Yu H, Shulenin S, Hidaka H, Kojima H, Allikmets R, Sakuma N, Pegoraro R, Srivastava AK, Salen G, Dean M, Patel SB. Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption. Nat Genet. 2001 Jan; 27(1):79-83. PMID: 11138003.
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    44. Yu H, Lee MH, Starck L, Elias ER, Irons M, Salen G, Patel SB, Tint GS. Spectrum of Delta(7)-dehydrocholesterol reductase mutations in patients with the Smith-Lemli-Opitz (RSH) syndrome. Hum Mol Genet. 2000 May 22; 9(9):1385-91. PMID: 10814720.
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    45. Yu H, Tint GS, Salen G, Patel SB. Detection of a common mutation in the RSH or Smith-Lemli-Opitz syndrome by a PCR-RFLP assay: IVS8-G-->C is found in over sixty percent of US propositi. Am J Med Genet. 2000 Feb 14; 90(4):347-50. PMID: 10710236.
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    46. Ngan HY, Liu SS, Yu H, Liu KL, Cheung AN. Proto-oncogenes and p53 protein expression in normal cervical stratified squamous epithelium and cervical intra-epithelial neoplasia. Eur J Cancer. 1999 Oct; 35(10):1546-50. PMID: 10673985.
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    47. Orr RK, Hoehn JL, Col NF. The learning curve for sentinel node biopsy in breast cancer: practical considerations. Arch Surg. 1999 Jul; 134(7):764-7. PMID: 24117880.
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