Joachim de Klerk Uys

Title
InstitutionMedical University of South Carolina
DepartmentCell and Molecular Pharmacology and Experimental Therapeutics
AddressP.O. Box MSC 509
DDB 409
Drug Discovery Building - 70 President St.
Phone843-876-2348
Fax843-792-2475
vCardDownload vCard

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Kruyer A, Ball LE, Townsend DM, Kalivas PW, Uys JD. Post-translational S-glutathionylation of cofilin increases actin cycling during cocaine seeking. PLoS One. 2019; 14(9):e0223037. PMID: 31550273.
      Citations:    
    2. Womersley JS, Townsend DM, Kalivas PW, Uys JD. Targeting redox regulation to treat substance use disorder using N-acetylcysteine Eur J Neurosci. 2019 08; 50(3):2538-2551. PMID: 30144182.
      Citations:    
    3. Hedges DM, Obray JD, Yorgason JT, Jang EY, Weerasekara VK, Uys JD, Bellinger FP, Steffensen SC. Methamphetamine Induces Dopamine Release in the Nucleus Accumbens Through a Sigma Receptor-Mediated Pathway. Neuropsychopharmacology. 2018 05; 43(6):1405-1414. PMID: 29185481.
      Citations:    
    4. Pulkoski-Gross MJ, Uys JD, Orr-Gandy KA, Coant N, Bialkowska AB, Szulc ZM, Bai A, Bielawska A, Townsend DM, Hannun YA, Obeid LM, Snider AJ. Novel sphingosine kinase-1 inhibitor, LCL351, reduces immune responses in murine DSS-induced colitis. Prostaglandins Other Lipid Mediat. 2017 05; 130:47-56. PMID: 28377281.
      Citations:    
    5. Nimitvilai S, Uys JD, Woodward JJ, Randall PK, Ball LE, Williams RW, Jones BC, Lu L, Grant KA, Mulholland PJ. Orbitofrontal Neuroadaptations and Cross-Species Synaptic Biomarkers in Heavy-Drinking Macaques. J Neurosci. 2017 03 29; 37(13):3646-3660. PMID: 28270566.
      Citations:    
    6. Womersley JS, Uys JD. S-Glutathionylation and Redox Protein Signaling in Drug Addiction. Prog Mol Biol Transl Sci. 2016; 137:87-121. PMID: 26809999.
      Citations:    
    7. Uys JD, McGuier NS, Gass JT, Griffin WC, Ball LE, Mulholland PJ. Chronic intermittent ethanol exposure and withdrawal leads to adaptations in nucleus accumbens core postsynaptic density proteome and dendritic spines. Addict Biol. 2016 May; 21(3):560-74. PMID: 25787124.
      Citations:    
    8. Qanungo S, Uys JD, Manevich Y, Distler AM, Shaner B, Hill EG, Mieyal JJ, Lemasters JJ, Townsend DM, Nieminen AL. N-acetyl-L-cysteine sensitizes pancreatic cancers to gemcitabine by targeting the NF?B pathway. Biomed Pharmacother. 2014 Sep; 68(7):855-64. PMID: 25257100.
      Citations:    
    9. Uys JD, Mulholland PJ, Townsend DM. Glutathione and redox signaling in substance abuse. Biomed Pharmacother. 2014 Jul; 68(6):799-807. PMID: 25027386.
      Citations:    
    10. Mack JT, Brown CB, Garrett TE, Uys JD, Townsend DM, Tew KD. Ablation of the ATP-binding cassette transporter, Abca2 modifies response to estrogen-based therapies. Biomed Pharmacother. 2012 Sep; 66(6):403-8. PMID: 22898081.
      Citations:    
    11. Grek CL, Townsend DM, Uys JD, Manevich Y, Coker WJ, Pazoles CJ, Tew KD. S-glutathionylated serine proteinase inhibitors as plasma biomarkers in assessing response to redox-modulating drugs. Cancer Res. 2012 May 01; 72(9):2383-93. PMID: 22406622.
      Citations:    
    12. Uys JD, Knackstedt L, Hurt P, Tew KD, Manevich Y, Hutchens S, Townsend DM, Kalivas PW. Cocaine-induced adaptations in cellular redox balance contributes to enduring behavioral plasticity. Neuropsychopharmacology. 2011 Nov; 36(12):2551-60. PMID: 21796101.
      Citations:    
    13. Xiong Y, Uys JD, Tew KD, Townsend DM. S-glutathionylation: from molecular mechanisms to health outcomes. Antioxid Redox Signal. 2011 Jul 01; 15(1):233-70. PMID: 21235352.
      Citations:    
    14. Tew KD, Manevich Y, Grek C, Xiong Y, Uys J, Townsend DM. The role of glutathione S-transferase P in signaling pathways and S-glutathionylation in cancer. Free Radic Biol Med. 2011 Jul 15; 51(2):299-313. PMID: 21558000.
      Citations:    
    15. Reissner KJ, Uys JD, Schwacke JH, Comte-Walters S, Rutherford-Bethard JL, Dunn TE, Blumer JB, Schey KL, Kalivas PW. AKAP signaling in reinstated cocaine seeking revealed by iTRAQ proteomic analysis. J Neurosci. 2011 Apr 13; 31(15):5648-58. PMID: 21490206.
      Citations:    
    16. Uys JD, Xiong Y, Townsend DM. Nitrosative stress-induced S-glutathionylation of protein disulfide isomerase. Methods Enzymol. 2011; 490:321-32. PMID: 21266258.
      Citations:    
    17. Uys JD, Reissner KJ. Glutamatergic neuroplasticity in cocaine addiction. Prog Mol Biol Transl Sci. 2011; 98:367-400. PMID: 21199777.
      Citations:    
    18. Uys JD, Manevich Y, Devane LC, He L, Garret TE, Pazoles CJ, Tew KD, Townsend DM. Preclinical pharmacokinetic analysis of NOV-002, a glutathione disulfide mimetic. Biomed Pharmacother. 2010 Sep; 64(7):493-8. PMID: 20359856.
      Citations:    
    19. Uys JD, Grey AC, Wiggins A, Schwacke JH, Schey KL, Kalivas PW. Matrix-assisted laser desorption/ionization tissue profiling of secretoneurin in the nucleus accumbens shell from cocaine-sensitized rats. J Mass Spectrom. 2010 Jan; 45(1):97-103. PMID: 19918966.
      Citations:    
    20. Uys JD, LaLumiere RT. Glutamate: the new frontier in pharmacotherapy for cocaine addiction. CNS Neurol Disord Drug Targets. 2008 Nov; 7(5):482-91. PMID: 19128205.
      Citations:    
    21. Uys JD, Hattingh SM, Stein DJ, Daniels WM. Large scale hippocampal cellular distress may explain the behavioral consequences of repetitive traumatic experiences--a proteomic approach. Neurochem Res. 2008 Sep; 33(9):1724-34. PMID: 18307038.
      Citations:    
    22. Uys JD, Stein DJ, Daniels WM. Neuroproteomics: relevance to anxiety disorders. Curr Psychiatry Rep. 2006 Aug; 8(4):286-90. PMID: 16879792.
      Citations:    
    Uys's Networks
    Click the
    Explore
    buttons for more information and interactive visualizations!
    Concepts (151)
    Explore
    _
    Co-Authors (21)
    Explore
    _
    Similar People (60)
    Explore
    _
    Same Department Expand Description
    Explore
    _
    Physical Neighbors
    _