John Terrill Huggins

Title
InstitutionMedical University of South Carolina
DepartmentMedicine
AddressP.O. Box MSC 630
Clinical Science Bldg. - 96 Jonathan Lucas St.
Phone843-792-2296
Fax843-876-2057
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    Pulmonary Arterial Hypertension (PAH), Cancer, Lung, Drug Studies, Pulmonary

    Collapse ORNG Applications 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Nickols NG, Mi Z, DeMatt E, Biswas K, Clise CE, Huggins JT, Maraka S, Ambrogini E, Mirsaeidi MS, Levin ER, Becker DJ, Makarov DV, Adorno Febles V, Belligund PM, Al-Ajam M, Muthiah MP, Montgomery RB, Robinson KW, Wong YN, Bedimo RJ, Villareal RC, Aguayo SM, Schoen MW, Goetz MB, Graber CJ, Bhattacharya D, Soo Hoo G, Orshansky G, Norman LE, Tran S, Ghayouri L, Tsai S, Geelhoed M, Rettig MB. Effect of Androgen Suppression on Clinical Outcomes in Hospitalized Men With COVID-19: The HITCH Randomized Clinical Trial. JAMA Netw Open. 2022 04 01; 5(4):e227852. PMID: 35438754.
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    2. Chopra A, Hu K, Judson MA, Fabian T, Nabagiez JP, Feustel PJ, Fantauzzi J, Chieng H, Austin A, Vancavage R, Maldonado F, Rahman N, Huggins JT, Doelken P. Association between Drainage-Dependent Prolonged Air Leak after Partial Lung Resection and Clinical Outcomes: A Prospective Cohort Study. Ann Am Thorac Soc. 2022 03; 19(3):389-398. PMID: 34715010.
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    3. Hu K, Chopra A, Kurman J, Huggins JT. Management of complex pleural disease in the critically ill patient. J Thorac Dis. 2021 Aug; 13(8):5205-5222. PMID: 34527360.
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    4. Chopra A, Al-Tarbsheh AH, Shah NJ, Yaqoob H, Hu K, Feustel PJ, Ortiz-Pacheco R, Patel KM, Oweis J, Kozlova N, Zouridis S, Ahmad S, Epelbaum O, Chong WH, Huggins JT, Saha BK, Conuel E, Chieng H, Mullins J, Bajaj D, Shkolnik B, Vancavage R, Madisi N, Judson MA. Pneumothorax in critically ill patients with COVID-19 infection: Incidence, clinical characteristics and outcomes in a case control multicenter study. Respir Med. 2021 08; 184:106464. PMID: 34044224.
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    5. Bernstein EJ, Huggins JT, Hummers LK, Owens GM. Systemic sclerosis with associated interstitial lung disease: management considerations and future directions. Am J Manag Care. 2021 05; 27(7 Suppl):S138-S146. PMID: 34003617.
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    6. Chopra A, Highland KB, Kilb E, Huggins JT. The Relationship of Pleural and Pericardial Effusion With Pulmonary Hemodynamics in Patients With Pulmonary Hypertension. Am J Med Sci. 2021 06; 361(6):731-735. PMID: 33947586.
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    7. Malik MI, Fox N, Chopra A, Hughes HY, Washburn R, Huggins JT. Positive pleural fluid RT-PCR for virus detection in SARS-CoV-2 pneumonia. QJM. 2020 12 01; 113(12):888-889. PMID: 32936903.
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    8. Shkolnik B, Judson MA, Austin A, Hu K, D'souza M, Zumbrunn A, Huggins JT, Yucel R, Chopra A. Response. Chest. 2020 10; 158(4):1783-1784. PMID: 33036094.
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    9. Chong WH, Huggins JT, Chopra A. Characteristics of Pleural Effusion in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Pneumonia. Am J Med Sci. 2021 02; 361(2):281-284. PMID: 32951846.
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    10. Hu K, Chopra A, Huggins JT, Nanchal R. Pleural manometry: techniques, applications, and pitfalls. J Thorac Dis. 2020 May; 12(5):2759-2770. PMID: 32642184.
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    11. Shkolnik B, Judson MA, Austin A, Hu K, D'Souza M, Zumbrunn A, Huggins JT, Yucel R, Chopra A. Diagnostic Accuracy of Thoracic Ultrasonography to Differentiate Transudative From Exudative Pleural Effusion. Chest. 2020 08; 158(2):692-697. PMID: 32194059.
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    12. Lentz RJ, Shojaee S, Grosu HB, Rickman OB, Roller L, Pannu JK, DePew ZS, Debiane LG, Cicenia JC, Akulian J, Walston C, Sanchez TM, Davidson KR, Jagan N, Ahmad S, Gilbert C, Huggins JT, Chen H, Light RW, Yarmus L, Feller-Kopman D, Lee H, Rahman NM, Maldonado F. The Impact of Gravity vs Suction-driven Therapeutic Thoracentesis on Pressure-related Complications: The GRAVITAS Multicenter Randomized Controlled Trial. Chest. 2020 03; 157(3):702-711. PMID: 31711990.
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    13. Chopra A, Judson MA, Doelken P, Maldonado F, Rahman NM, Huggins JT. The Relationship of Pleural Manometry With Postthoracentesis Chest Radiographic Findings in Malignant Pleural Effusion. Chest. 2020 02; 157(2):421-426. PMID: 31472154.
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    14. Velez JCQ, Petkovich B, Karakala N, Huggins JT. Point-of-Care Echocardiography Unveils Misclassification of Acute Kidney Injury as Hepatorenal Syndrome. Am J Nephrol. 2019; 50(3):204-211. PMID: 31394538.
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    15. Silver RM, Wilson DA, Akter T, Atanelishvili I, Huggins JT, Kajdasz K, Highland KB, Nietert PJ, Bogatkevich GS. Safety and Tolerability of Thrombin Inhibition in Scleroderma-Associated Interstitial Lung Disease. ACR Open Rheumatol. 2019 Sep; 1(7):403-411. PMID: 31777820.
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    16. Wuyts W, Antin-Ozerkis D, Huggins JT, LaCamera PP, Spagnolo P, Vašáková M, Wijsenbeek MS, Polman B, Kirchgaessler KU, Scholand MB. Serious adverse events in patients with idiopathic pulmonary fibrosis in the placebo arms of 6 clinical trials. Respir Med. 2019 04; 150:120-125. PMID: 30961937.
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    17. Lentz RJ, Lerner AD, Pannu JK, Merrick CM, Roller L, Walston C, Valenti S, Goddard T, Chen H, Huggins JT, Rickman OB, Yarmus L, Psallidas I, Rahman NM, Light RW, Maldonado F. Routine monitoring with pleural manometry during therapeutic large-volume thoracentesis to prevent pleural-pressure-related complications: a multicentre, single-blind randomised controlled trial. Lancet Respir Med. 2019 05; 7(5):447-455. PMID: 30772283.
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    18. Kolb M, Bondue B, Pesci A, Miyazaki Y, Song JW, Bhatt NY, Huggins JT, Oldham JM, Padilla ML, Roman J, Shapera S. Acute exacerbations of progressive-fibrosing interstitial lung diseases. Eur Respir Rev. 2018 Dec 31; 27(150). PMID: 30578331.
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    19. Brown KK, Flaherty KR, Cottin V, Raghu G, Inoue Y, Azuma A, Huggins JT, Richeldi L, Stowasser S, Stansen W, Schlenker-Herceg R, Maher TM, Wells AU. Lung function outcomes in the INPULSIS® trials of nintedanib in idiopathic pulmonary fibrosis. Respir Med. 2019 01; 146:42-48. PMID: 30665517.
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    20. Crestani B, Huggins JT, Kaye M, Costabel U, Glaspole I, Ogura T, Song JW, Stansen W, Quaresma M, Stowasser S, Kreuter M. Long-term safety and tolerability of nintedanib in patients with idiopathic pulmonary fibrosis: results from the open-label extension study, INPULSIS-ON. Lancet Respir Med. 2019 Jan; 7(1):60-68. PMID: 30224318.
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    21. Flaherty KR, Fell CD, Huggins JT, Nunes H, Sussman R, Valenzuela C, Petzinger U, Stauffer JL, Gilberg F, Bengus M, Wijsenbeek M. Safety of nintedanib added to pirfenidone treatment for idiopathic pulmonary fibrosis. Eur Respir J. 2018 08; 52(2). PMID: 29946005.
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    22. Huggins JT, Maldonado F, Chopra A, Rahman N, Light R. Unexpandable lung from pleural disease. Respirology. 2018 02; 23(2):160-167. PMID: 29064169.
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    23. Austin A, Jogani SN, Brasher PB, Argula RG, Huggins JT, Chopra A. The Urinothorax: A Comprehensive Review With Case Series. Am J Med Sci. 2017 07; 354(1):44-53. PMID: 28755732.
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    24. Ferreiro L, Sánchez-Sánchez R, Valdés L, Kummerfeldt CE, Huggins JT. Concordant and Discordant Exudates and Their Effect on the Accuracy of Light's Criteria to Diagnose Exudative Pleural Effusions. Am J Med Sci. 2016 Dec; 352(6):549-556. PMID: 27916209.
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    25. Svigals PZ, Chopra A, Ravenel JG, Nietert PJ, Huggins JT. The accuracy of pleural ultrasonography in diagnosing complicated parapneumonic pleural effusions. Thorax. 2017 01; 72(1):94-95. PMID: 27613540.
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    26. Wuyts WA, Kolb M, Stowasser S, Stansen W, Huggins JT, Raghu G. First Data on Efficacy and Safety of Nintedanib in Patients with Idiopathic Pulmonary Fibrosis and Forced Vital Capacity of =50 % of Predicted Value. Lung. 2016 10; 194(5):739-43. PMID: 27377558.
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    27. Bade BC, Callahan SP, Higuero JP, Pastis N, Huggins JT. 83-Year-Old Man With Chronic Kidney Disease, Fluid Overload, and Coronary Artery Disease Develops Altered Mental Status. Chest. 2016 Apr; 149(4):e111-4. PMID: 27055714.
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    28. Huggins JT, Doelken P, Walters C, Rockey DC. Point-of-Care Echocardiography Improves Assessment of Volume Status in Cirrhosis and Hepatorenal Syndrome. Am J Med Sci. 2016 May; 351(5):550-3. PMID: 27140719.
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    29. DiVietro ML, Huggins JT, Angotti LB, Kummerfeldt CE, Nestor JE, Doelken P, Sahn SA. Pleural Fluid Analysis in Chronic Hemothorax: A Mimicker of Infection. Clin Med Insights Case Rep. 2015; 8:71-6. PMID: 26309422.
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    30. Pastis NJ, Vanderbilt AA, Tanner NT, Silvestri GA, Huggins JT, Svigals Z, Shepherd RW. Construct validity of the Simbionix bronch mentor simulator for essential bronchoscopic skills. J Bronchology Interv Pulmonol. 2014 Oct; 21(4):314-21. PMID: 25321450.
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    31. Valdés L, Huggins JT, Gude F, Ferreiro L, Alvarez-Dobaño JM, Golpe A, Toubes ME, González-Barcala FJ, José ES, Sahn SA. Characteristics of patients with yellow nail syndrome and pleural effusion. Respirology. 2014 Oct; 19(7):985-92. PMID: 25123563.
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    32. Huggins JT, Karakala N, Campbell R, Kummerfeldt C, Nestor J, Pastis NJ, Doelken P. A 37-year-old woman with diabetes mellitus, systemic hypertension, and chronic kidney disease admitted with multifocal pneumonia and empyema. Chest. 2014 Aug; 146(2):e41-e46. PMID: 25091761.
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    33. Kummerfeldt CE, Chiuzan CC, Huggins JT, DiVietro ML, Nestor JE, Sahn SA, Doelken P. Improving the predictive accuracy of identifying exudative effusions. Chest. 2014 Mar 01; 145(3):586-592. PMID: 24008773.
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    34. Doelken P, Huggins JT, Goldblatt M, Nietert P, Sahn SA. Effects of coexisting pneumonia and end-stage renal disease on pleural fluid analysis in patients with hydrostatic pleural effusion. Chest. 2013 Jun; 143(6):1709-1716. PMID: 23288037.
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    35. Sahn SA, Huggins JT, San José ME, Álvarez-Dobaño JM, Valdés L. Can tuberculous pleural effusions be diagnosed by pleural fluid analysis alone? Int J Tuberc Lung Dis. 2013 Jun; 17(6):787-93. PMID: 23676163.
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    36. Lal C, Huggins JT, Sahn SA. Parasitic diseases of the pleura. Am J Med Sci. 2013 May; 345(5):385-9. PMID: 22990049.
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    37. Kummerfeldt CE, Huggins JT, Riemer EC, Ravenel JG, Whelan TP, Sahn SA. Pulmonary capillaritis in a patient with moderately positive anti-PL-12 antibodies. Int J Rheum Dis. 2013 Apr; 16(2):233-4. PMID: 23773650.
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    38. Kummerfeldt CE, Huggins JT, Sahn SA. Unusual bacterial infections and the pleura. Open Respir Med J. 2012; 6:75-81. PMID: 22977649.
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    39. Huggins JT, Doelken P, Sahn SA. Intrapleural therapy. Respirology. 2011 Aug; 16(6):891-9. PMID: 21672085.
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    40. Wang Memoli JS, El-Bayoumi E, Pastis NJ, Tanner NT, Gomez M, Huggins JT, Onicescu G, Garrett-Mayer E, Armeson K, Taylor KK, Silvestri GA. Using endobronchial ultrasound features to predict lymph node metastasis in patients with lung cancer. Chest. 2011 Dec; 140(6):1550-1556. PMID: 21636663.
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    41. Gurung P, Goldblatt M, Huggins JT, Doelken P, Nietert PJ, Sahn SA. Pleural fluid analysis and radiographic, sonographic, and echocardiographic characteristics of hepatic hydrothorax. Chest. 2011 Aug; 140(2):448-453. PMID: 21273292.
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    42. Huggins JT. Chylothorax and cholesterol pleural effusion. Semin Respir Crit Care Med. 2010 Dec; 31(6):743-50. PMID: 21213206.
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    43. Huggins JT, Doelken P, Sahn SA. The unexpandable lung. F1000 Med Rep. 2010 Oct 21; 2:77. PMID: 21173837.
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    44. Goldblatt M, Huggins JT, Doelken P, Gurung P, Sahn SA. Dasatinib-induced pleural effusions: a lymphatic network disorder? Am J Med Sci. 2009 Nov; 338(5):414-7. PMID: 19838099.
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    45. Kalluri M, Huggins JT, Strange C. A 56-year-old woman with arm pain, dyspnea, and an elevated diaphragm. Chest. 2008 Jan; 133(1):296-9. PMID: 18187758.
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    46. Heidecker J, Huggins JT, Sahn SA, Doelken P. Pathophysiology of pneumothorax following ultrasound-guided thoracentesis. Chest. 2006 Oct; 130(4):1173-84. PMID: 17035453.
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    47. Huggins JT, Doelken P. Pleural manometry. Clin Chest Med. 2006 Jun; 27(2):229-40. PMID: 16716815.
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    48. Huggins JT, Doelken P, Sahn SA, King L, Judson MA. Pleural effusions in a series of 181 outpatients with sarcoidosis. Chest. 2006 Jun; 129(6):1599-604. PMID: 16778281.
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    49. Almoosa KF, Ryu JH, Mendez J, Huggins JT, Young LR, Sullivan EJ, Maurer J, McCormack FX, Sahn SA. Management of pneumothorax in lymphangioleiomyomatosis: effects on recurrence and lung transplantation complications. Chest. 2006 May; 129(5):1274-81. PMID: 16685019.
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    50. Vincent B, Huggins JT, Doelken P, Silvestri G. Successful real-time endobronchial ultrasound-guided transbronchial needle aspiration of a hilar lung mass obtained by traversing the pulmonary artery. J Thorac Oncol. 2006 May; 1(4):362-4. PMID: 17409884.
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    51. Doelken P, Huggins JT, Pastis NJ, Sahn SA. Pleural manometry: technique and clinical implications. Chest. 2004 Dec; 126(6):1764-9. PMID: 15596671.
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    52. Huggins JT, Sahn SA. Causes and management of pleural fibrosis. Respirology. 2004 Nov; 9(4):441-7. PMID: 15612954.
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    53. Huggins JT, Kaplan A, Martin-Harris B, Sahn SA. Eucalyptus as a specific irritant causing vocal cord dysfunction. Ann Allergy Asthma Immunol. 2004 Sep; 93(3):299-303. PMID: 15478393.
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    54. Huggins JT, Sahn SA. Drug-induced pleural disease. Clin Chest Med. 2004 Mar; 25(1):141-53. PMID: 15062606.
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    55. Huggins JT, Sahn SA. Duro-pleural fistula diagnosed by beta2-transferrin. Respiration. 2003 Jul-Aug; 70(4):423-5. PMID: 14512681.
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    56. Orr RK, Hoehn JL, Col NF. The learning curve for sentinel node biopsy in breast cancer: practical considerations. Arch Surg. 1999 Jul; 134(7):764-7. PMID: 15078722.
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    57. Orr RK, Hoehn JL, Col NF. The learning curve for sentinel node biopsy in breast cancer: practical considerations. Arch Surg. 1999 Jul; 134(7):764-7. PMID: 17218577.
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