Julianne C. Flanagan

Title
InstitutionMedical University of South Carolina
DepartmentPsychiatry and Behavioral Sciences
AddressP.O. Box MSC 861
Suite 151
Charleston Center - 5 Charleston Center Drive, Cha
Phone843-792-5569
Fax843-792-5932
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    Dr. Flanagan's program of research focuses on the relationships between post-traumatic stress disorder, substance use disorders, and interpersonal violence. She is currently conducting laboratory and treatment development studies aimed at better understanding behavioral and neurobiological underpinnings of violence among individuals and couples. She is also conducting studies examining behavioral and pharmacological interventions to mitigate these commonly co-occurring problems. Dr. Flanagan has received training support from NIAAA, NIDA, and NICHD/ORWH.
    Collapse keywords
    Drug Studies, Psychiatry, Healthy Volunteer Studies, Substance Use, Mental Health, Stress Disorders, Alcohol, PTSD, interpersonal violence, treatment development, oxytocin

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Flanagan JC, Nietert PJ, Sippel L, Jarnecke AM, Kirby C, Hogan JN, Massa AA, Brower J, Back SE, Parrott D. A randomized controlled trial examining the effects of intranasal oxytocin on alcohol craving and intimate partner aggression among couples. J Psychiatr Res. 2022 08; 152:14-24. PMID: 35709548.
      Citations:    
    2. Hogan JN, Garcia AM, Tomko RL, Squeglia LM, Flanagan JC. Parent-Child Concordance and Discordance in Family Violence Reporting: A Descriptive Analysis from the Adolescent Brain Cognitive Development Study®. J Interpers Violence. 2022 May 07; 8862605221081928. PMID: 35531607.
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    3. Saraiya TC, Badour CL, Jones AC, Jarnecke AM, Brown DG, Flanagan JC, Killeen TK, Back SE. The role of posttraumatic guilt and anger in integrated treatment for PTSD and co-occurring substance use disorders among primarily male veterans. Psychol Trauma. 2022 Jan 13. PMID: 35025558.
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    4. Badour CL, Flanagan JC, Allan NP, Gilmore AK, Gros DF, Killeen T, Korte KJ, Brown DG, Kolnogorova K, Back SE. Temporal dynamics of symptom change among veterans receiving an integrated treatment for posttraumatic stress disorder and substance use disorders. J Trauma Stress. 2022 04; 35(2):546-558. PMID: 34773928.
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    5. Hahn CK, Jarnecke AM, Calhoun C, Melkonian A, Flanagan JC, Back SE. Sexual Harassment and Assault During Deployment: Associations with Treatment Outcomes Among Veterans with Co-occurring PTSD and SUD. Mil Psychol. 2022; 34(1):12-22. PMID: 35340543.
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    6. Peterson AL, Young-McCaughan S, Roache JD, Mintz J, Litz BT, Williamson DE, Resick PA, Foa EB, McGeary DD, Dondanville KA, Taylor DJ, Wachen JS, Fox PT, Bryan CJ, McLean CP, Pruiksma KE, Yarvis JS, Niles BL, Abdallah CG, Averill LA, Back SE, Baker MT, Blount TH, Borah AM, Borah EV, Brock MS, Brown LA, Burg MM, Cigrang JA, DeBeer BB, DeVoe ER, Fina BA, Flanagan JC, Fredman SJ, Gardner CL, Gatchel RR, Goodie JL, Gueorguieva R, Higgs JB, Jacoby VM, Kelly KM, Krystal JH, Lapiz-Bluhm MD, López-Roca AL, Marx BP, Maurer DM, McDevitt-Murphy ME, McGeary CA, Meyer EC, Miles SR, Monson CM, Morilak DA, Moring JC, Mysliwiec V, Nicholson KL, Rauch SAM, Riggs DS, Rosen CS, Rudd MD, Schobitz RP, Schrader CC, Shinn AM, Shiroma PR, Sloan DM, Stern SL, Strong R, Vannoy SD, Young KA, Keane TM. STRONG STAR and the Consortium to Alleviate PTSD: Shaping the future of combat PTSD and related conditions in military and veteran populations. Contemp Clin Trials. 2021 11; 110:106583. PMID: 34600107.
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    7. Henschel AV, Flanagan JC, Augur IF, Jeffirs SM, Back SE. Motives for prescription opioid use: The role of alexithymia and distress tolerance. Am J Addict. 2022 01; 31(1):55-60. PMID: 34570408.
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    8. Weiss NH, Hogan J, Brem M, Massa AA, Kirby CM, Flanagan JC. Advancing our understanding of the intersection between emotion regulation and alcohol and drug use problems: Dyadic analysis in couples with intimate partner violence and alcohol use disorder. Drug Alcohol Depend. 2021 11 01; 228:109066. PMID: 34610519.
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    9. Sippel LM, Flanagan JC, Holtzheimer PE, Moran-Santa-Maria MM, Brady KT, Joseph JE. Effects of intranasal oxytocin on threat- and reward-related functional connectivity in men and women with and without childhood abuse-related PTSD. Psychiatry Res Neuroimaging. 2021 11 30; 317:111368. PMID: 34455213.
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    10. Crum KI, Flanagan JC, Vaughan B, Aloi J, Moran-Santa Maria MM, Back SE, Brady KT, Joseph JE. Oxytocin, PTSD, and sexual abuse are associated with attention network intrinsic functional connectivity. Psychiatry Res Neuroimaging. 2021 10 30; 316:111345. PMID: 34371478.
      Citations:    
    11. Melkonian AJ, Flanagan JC, Calhoun CD, Hogan JN, Back SE. Craving Moderates the Effects of Intranasal Oxytocin on Anger in Response to Social Stress Among Veterans With Co-Occurring Posttraumatic Stress Disorder and Alcohol Use Disorder. J Clin Psychopharmacol. 2021 Jul-Aug 01; 41(4):465-469. PMID: 34121063.
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    12. McCrady BS, Flanagan JC. The Role of the Family in Alcohol Use Disorder Recovery for Adults. Alcohol Res. 2021; 41(1):06. PMID: 33981521.
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    13. Gilmore AK, McKee G, Flanagan JC, Leone RM, Oesterle DW, Kirby CM, Short N, Gill-Hopple K. Medications at the Emergency Department After Recent Rape. J Interpers Violence. 2022 08; 37(15-16):NP12954-NP12972. PMID: 33736532.
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    14. Brown DG, Flanagan JC, Jarnecke A, Killeen TK, Back SE. Ethnoracial differences in treatment-seeking veterans with substance use disorders and co-occurring PTSD: Presenting characteristics and response to integrated exposure-based treatment. J Ethn Subst Abuse. 2022 Jul-Sep; 21(3):1141-1164. PMID: 33111647.
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    15. McClure EA, Baker NL, Hood CO, Tomko RL, Squeglia LM, Flanagan JC, Carpenter MJ, Gray KM. Cannabis and Alcohol Co-Use in a Smoking Cessation Pharmacotherapy Trial for Adolescents and Emerging Adults. Nicotine Tob Res. 2020 07 16; 22(8):1374-1382. PMID: 31612956.
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    16. Sippel LM, King CE, Wahlquist AE, Flanagan JC. A Preliminary Examination of Endogenous Peripheral Oxytocin in a Pilot Randomized Clinical Trial of Oxytocin-Enhanced Psychotherapy for Posttraumatic Stress Disorder. J Clin Psychopharmacol. 2020 Jul/Aug; 40(4):401-404. PMID: 32639293.
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    17. Jarnecke AM, Flanagan JC. Staying safe during COVID-19: How a pandemic can escalate risk for intimate partner violence and what can be done to provide individuals with resources and support. Psychol Trauma. 2020 Aug; 12(S1):S202-S204. PMID: 32551749.
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    18. Flanagan JC, Mitchell JM, Baker NL, Woolley J, Wangelin B, Back SE, McQuaid JR, Neylan TC, Wolfe WR, Brady KT. Enhancing prolonged exposure therapy for PTSD among veterans with oxytocin: Design of a multisite randomized controlled trial. Contemp Clin Trials. 2020 08; 95:106074. PMID: 32561468.
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    19. Hood CO, Tomko RL, Baker NL, Tuck BM, Flanagan JC, Carpenter MJ, Gray KM, Saladin ME, McClure EA. Examining sex, adverse childhood experiences, and oxytocin on neuroendocrine reactivity in smokers. Psychoneuroendocrinology. 2020 10; 120:104752. PMID: 32634745.
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    20. Flanagan JC, Jarnecke AM, Leone RM, Oesterle DW. Effects of couple conflict on alcohol craving: Does intimate partner violence play a role? Addict Behav. 2020 10; 109:106474. PMID: 32485550.
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    21. Flanagan JC, Leone RM, Gilmore AK, McClure EA, Gray KM. Association of Cannabis Use With Intimate Partner Violence Among Couples With Substance Misuse. Am J Addict. 2020 07; 29(4):323-330. PMID: 32219903.
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    22. Back SE, Gray K, Santa Ana E, Jones JL, Jarnecke AM, Joseph JE, Prisciandaro J, Killeen T, Brown DG, Taimina L, Compean E, Malcolm R, Flanagan JC, Kalivas PW. N-acetylcysteine for the treatment of comorbid alcohol use disorder and posttraumatic stress disorder: Design and methodology of a randomized clinical trial. Contemp Clin Trials. 2020 04; 91:105961. PMID: 32087337.
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    23. Leone RM, Jarnecke AM, Back SE, Brady KT, Flanagan JC. The moderating role of infidelity on the relation between oxytocin and conflict behaviors among substance misusing couples. Exp Clin Psychopharmacol. 2020 Jun; 28(3):251-257. PMID: 31556677.
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    24. Gilmore AK, Davidson TM, Leone RM, Wray LB, Oesterle DW, Hahn CK, Flanagan JC, Gill-Hopple K, Acierno R. Usability Testing of a Mobile Health Intervention to Address Acute Care Needs after Sexual Assault. Int J Environ Res Public Health. 2019 08 25; 16(17). PMID: 31450676.
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    25. Flanagan JC, Sippel LM, Santa Maria MMM, Hartwell KJ, Brady KT, Joseph JE. Impact of Oxytocin on the neural correlates of fearful face processing in PTSD related to childhood Trauma. Eur J Psychotraumatol. 2019; 10(1):1606626. PMID: 31105906.
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    26. Flanagan JC, Joseph JE, Nietert PJ, Back SE, McCrady BS. Design of a randomized controlled trial examining the efficacy of oxytocin to enhance alcohol behavioral couple therapy. Contemp Clin Trials. 2019 07; 82:1-8. PMID: 31063869.
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    27. Flanagan JC, Mitchell JM. Augmenting Treatment for Posttraumatic Stress Disorder and Co-Occurring Conditions with Oxytocin. Curr Treat Options Psychiatry. 2019 Jun; 6(2):132-142. PMID: 31763133.
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    28. Jeffirs SM, Jarnecke AM, Flanagan JC, Killeen TK, Laffey TF, Back SE. Veterans with PTSD and comorbid substance use disorders: Does single versus poly-substance use disorder affect treatment outcomes? Drug Alcohol Depend. 2019 06 01; 199:70-75. PMID: 31009834.
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    29. Gilmore AK, Flanagan JC. Acute mental health symptoms among individuals receiving a sexual assault medical forensic exam: the role of previous intimate partner violence victimization. Arch Womens Ment Health. 2020 02; 23(1):81-89. PMID: 30762148.
      Citations:    
    30. Flanagan JC, Yonce S, Calhoun CD, Back SE, Brady KT, Joseph JE. Preliminary development of a neuroimaging paradigm to examine neural correlates of relationship conflict. Psychiatry Res Neuroimaging. 2019 01 30; 283:125-134. PMID: 30581042.
      Citations:    
    31. Gilmore AK, Jaffe AE, Hahn CK, Ridings LE, Gill-Hopple K, Lazenby GB, Flanagan JC. Intimate Partner Violence and Completion of Post-Sexual Assault Medical Forensic Examination Follow-Up Screening. J Interpers Violence. 2021 07; 36(13-14):5991-6004. PMID: 34121495.
      Citations:    
    32. Back SE, Killeen T, Badour CL, Flanagan JC, Allan NP, Ana ES, Lozano B, Korte KJ, Foa EB, Brady KT. Concurrent treatment of substance use disorders and PTSD using prolonged exposure: A randomized clinical trial in military veterans. Addict Behav. 2019 03; 90:369-377. PMID: 30529244.
      Citations:    
    33. Flanagan JC, Allan NP, Calhoun CD, Badour CL, Moran-Santa Maria M, Brady KT, Back SE. Effects of oxytocin on stress reactivity and craving in veterans with co-occurring PTSD and alcohol use disorder. Exp Clin Psychopharmacol. 2019 Feb; 27(1):45-54. PMID: 30382728.
      Citations:    
    34. Jarnecke AM, Allan NP, Badour CL, Flanagan JC, Killeen TK, Back SE. Substance use disorders and PTSD: Examining substance use, PTSD symptoms, and dropout following imaginal exposure. Addict Behav. 2019 03; 90:35-39. PMID: 30355535.
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    35. Jarnecke AM, Barden E, Back SE, Brady KT, Flanagan JC. Intimate partner violence moderates the association between oxytocin and reactivity to dyadic conflict among couples. Psychiatry Res. 2018 12; 270:404-411. PMID: 30308464.
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    36. Back SE, Flanagan JC, Jones JL, Augur I, Peterson AL, Young-McCaughan S, Shirley DW, Henschel A, Joseph JE, Litz BT, Hancock AK, Roache JD, Mintz J, Wachen JS, Keane TM, Brady KT. Doxazosin for the treatment of co-occurring PTSD and alcohol use disorder: Design and methodology of a randomized controlled trial in military veterans. Contemp Clin Trials. 2018 10; 73:8-15. PMID: 30145268.
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    37. Solomon DT, Nietert PJ, Calhoun C, Smith DW, Back SE, Barden E, Brady KT, Flanagan JC. Effects of Oxytocin on Emotional and Physiological Responses to Conflict in Couples with Substance Misuse. Couple Family Psychol. 2018 Jun; 7(2):91-102. PMID: 30740265.
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    38. Flanagan JC, Jones JL, Jarnecke AM, Back SE. Behavioral Treatments for Alcohol Use Disorder and Post-Traumatic Stress Disorder. Alcohol Res. 2018; 39(2):181-192. PMID: 31198657.
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    39. Flanagan JC, Sippel LM, Wahlquist A, Moran-Santa Maria MM, Back SE. Augmenting Prolonged Exposure therapy for PTSD with intranasal oxytocin: A randomized, placebo-controlled pilot trial. J Psychiatr Res. 2018 03; 98:64-69. PMID: 29294429.
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    40. Flanagan JC, Fischer MS, Nietert PJ, Back SE, Maria MM, Snead A, Brady KT. Effects of oxytocin on cortisol reactivity and conflict resolution behaviors among couples with substance misuse. Psychiatry Res. 2018 02; 260:346-352. PMID: 29232576.
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    41. Bountress KE, Badour C, Flanagan J, Gilmore AK, Back SE. Treatment of co-occurring posttraumatic stress disorder and substance use: Does order of onset influence outcomes? Psychol Trauma. 2018 Nov; 10(6):662-665. PMID: 28771018.
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    42. Flanagan JC, Fischer MS, Badour CL, Ornan G, Killeen TK, Back SE. The Role of Relationship Adjustment in an Integrated Individual Treatment for PTSD and Substance Use Disorders Among Veterans: An Exploratory Study. J Dual Diagn. 2017 Jul-Sep; 13(3):213-218. PMID: 28541802.
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    43. Szafranski DD, Snead A, Allan NP, Gros DF, Killeen T, Flanagan J, Pericot-Valverde I, Back SE. Integrated, exposure-based treatment for PTSD and comorbid substance use disorders: Predictors of treatment dropout. Addict Behav. 2017 10; 73:30-35. PMID: 28460246.
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    44. Badour CL, Flanagan JC, Gros DF, Killeen T, Pericot-Valverde I, Korte KJ, Allan NP, Back SE. Habituation of distress and craving during treatment as predictors of change in PTSD symptoms and substance use severity. J Consult Clin Psychol. 2017 Mar; 85(3):274-281. PMID: 28221062.
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    45. Gros DF, Flanagan JC, Korte KJ, Mills AC, Brady KT, Back SE. Relations among social support, PTSD symptoms, and substance use in veterans. Psychol Addict Behav. 2016 Nov; 30(7):764-770. PMID: 27786511.
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    46. Flanagan JC, Korte KJ, Killeen TK, Back SE. Concurrent Treatment of Substance Use and PTSD. Curr Psychiatry Rep. 2016 08; 18(8):70. PMID: 27278509.
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    47. Adams ZW, McCauley JL, Back SE, Flanagan JC, Hanson RF, Killeen TK, Danielson CK. Clinician Perspectives on Treating Adolescents with Co-occurring Post-Traumatic Stress Disorder, Substance Use, and Other Problems. J Child Adolesc Subst Abuse. 2016; 25(6):575-583. PMID: 27840568.
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    48. Flanagan JC, Hakes JK, McClure EA, Snead AL, Back SE. Effects of intimate partner violence, PTSD, and alcohol use on cigarette smoking in a nationally representative sample. Am J Addict. 2016 06; 25(4):283-90. PMID: 27196699.
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    49. Sullivan TP, Weiss NH, Flanagan JC, Willie TC, Armeli S, Tennen H. PTSD and Daily Co-Occurrence of Drug and Alcohol Use Among Women Experiencing Intimate Partner Violence. J Dual Diagn. 2016; 12(1):36-42. PMID: 26828635.
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    50. Forbes MK, Flanagan JC, Barrett EL, Crome E, Baillie AJ, Mills KL, Teesson M. Smoking, posttraumatic stress disorder, and alcohol use disorders in a nationally representative sample of Australian men and women. Drug Alcohol Depend. 2015 Nov 01; 156:176-183. PMID: 26386825.
      Citations:    
    51. Back SE, Gros DF, Price M, LaRowe S, Flanagan J, Brady KT, Davis C, Jaconis M, McCauley JL. Laboratory-induced stress and craving among individuals with prescription opioid dependence. Drug Alcohol Depend. 2015 Oct 01; 155:60-7. PMID: 26342626.
      Citations:    
    52. Flanagan JC, Baker NL, McRae-Clark AL, Brady KT, Moran-Santa Maria MM. Effects of adverse childhood experiences on the association between intranasal oxytocin and social stress reactivity among individuals with cocaine dependence. Psychiatry Res. 2015 Sep 30; 229(1-2):94-100. PMID: 26231584.
      Citations:    
    53. Jobe-Shields L, Flanagan JC, Killeen T, Back SE. Family composition and symptom severity among Veterans with comorbid PTSD and substance use disorders. Addict Behav. 2015 Nov; 50:117-23. PMID: 26132535.
      Citations:    
    54. Flanagan JC, Barrett EL, Crome E, Forbes M. Developing International Collaborations for Early Career Researchers in Psychology. Behav Ther (N Y N Y). 2015 Jun; 38(5):131-134. PMID: 27453624.
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    55. Flanagan JC, Gordon KC, Moore TM, Stuart GL. Women's Stress, Depression, and Relationship Adjustment Profiles as They Relate to Intimate Partner Violence and Mental Health During Pregnancy and Postpartum. Psychol Violence. 2015 Jan; 5(1):66-73. PMID: 25642352.
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    56. Moran-Santa Maria MM, Flanagan J, Brady K. Ovarian hormones and drug abuse. Curr Psychiatry Rep. 2014 Nov; 16(11):511. PMID: 25224609.
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    57. Jaquier V, Flanagan JC, Sullivan TP. Anxiety and posttraumatic stress symptom pathways to substance use problems among community women experiencing intimate partner violence. Anxiety Stress Coping. 2015; 28(4):445-55. PMID: 25251694.
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    58. Flanagan JC, Jaquier V, Overstreet N, Swan SC, Sullivan TP. The mediating role of avoidance coping between intimate partner violence (IPV) victimization, mental health, and substance abuse among women experiencing bidirectional IPV. Psychiatry Res. 2014 Dec 15; 220(1-2):391-6. PMID: 25174851.
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    59. Flanagan JC. Of women seeking assistance for intimate partner violence, those who report victimisation during pregnancy are at higher risk of further victimisation. Evid Based Nurs. 2015 Apr; 18(2):38. PMID: 25056870.
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    60. Back SE, Gros DF, McCauley JL, Flanagan JC, Cox E, Barth KS, Brady KT. Laboratory-induced cue reactivity among individuals with prescription opioid dependence. Addict Behav. 2014 Aug; 39(8):1217-23. PMID: 24813546.
      Citations:    
    61. Flanagan JC, Teer A, Beylotte FM, Killeen TK, Back SE. Correlates of Recent and Lifetime Aggression among Veterans with Co-Occurring PTSD and Substance Use Disorders. Ment Health Subst Use. 2014; 7(4):315-328. PMID: 25419233.
      Citations:    
    62. Orr RK, Hoehn JL, Col NF. The learning curve for sentinel node biopsy in breast cancer: practical considerations. Arch Surg. 1999 Jul; 134(7):764-7. PMID: 26249027.
      Citations:    
    63. Orr RK, Hoehn JL, Col NF. The learning curve for sentinel node biopsy in breast cancer: practical considerations. Arch Surg. 1999 Jul; 134(7):764-7. PMID: 30070567.
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    64. Orr RK, Hoehn JL, Col NF. The learning curve for sentinel node biopsy in breast cancer: practical considerations. Arch Surg. 1999 Jul; 134(7):764-7. PMID: 35589850.
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