Kristin Wallace

Title
InstitutionMedical University of South Carolina
DepartmentPublic Health Sciences
AddressP.O. Box MSC 955
BE103
68 President St.
Phone843-876-2432
Fax843-876-2344
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    Dr. Wallace’s research focuses on understanding the factors that contribute to the racial disparities in colorectal cancer carcinogenesis through examining differences in population-level tumor pathologies. She is currently investigating the relationship between race and the decision to undergo treatment of stage IV colorectal adenocarcinoma using hospital-based clinical data.
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    Disease Prevention, Minorities, Inflammation, Cancer, Cancer/Gastrointestinal, Immune System, Colonoscopy

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Howell AV, Gebregziabher M, Thiers BH, Graboyes EM, Paulos CM, Wrangle JM, Hunt KJ, Wallace K. Association of age with survival in older patients with cutaneous melanoma treated with immune checkpoint inhibitors. J Geriatr Oncol. 2022 Sep; 13(7):1003-1010. PMID: 35660090.
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    2. Jones SK, Wolf BJ, Froeliger B, Wallace K, Carpenter MJ, Alberg AJ. Nicotine Metabolism Predicted by CYP2A6 Genotypes in Relation to Smoking Cessation: A Systematic Review. Nicotine Tob Res. 2022 03 26; 24(5):633-642. PMID: 34478556.
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    3. Wallace K, El Nahas GJ, Bookhout C, Thaxton JE, Lewin DN, Nikolaishvili-Feinberg N, Cohen SM, Brazeal JG, Hill EG, Wu JD, Baron JA, Alekseyenko AV. Immune Responses Vary in Preinvasive Colorectal Lesions by Tumor Location and Histology. Cancer Prev Res (Phila). 2021 09; 14(9):885-892. PMID: 34341013.
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    4. Wallace K, Nahhas GJ, Bookhout C, Lewin DN, Paulos CM, Nikolaishvili-Feinberg N, Cohen SM, Guglietta S, Bakhtiari A, Camp ER, Hill EG, Baron JA, Wu JD, Alekseyenko AV. Preinvasive Colorectal Lesions of African Americans Display an Immunosuppressive Signature Compared to Caucasian Americans. Front Oncol. 2021; 11:659036. PMID: 33987094.
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    5. Pécot T, Alekseyenko A, Wallace K. A deep learning segmentation strategy that minimizes the amount of manually annotated images. F1000Res. 2021; 10:256. PMID: 35136569.
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    6. Curran T, Sun Z, Gerry B, Findlay VJ, Wallace K, Li Z, Paulos C, Ford M, Rubinstein MP, Chung D, Camp ER. Differential immune signatures in the tumor microenvironment are associated with colon cancer racial disparities. Cancer Med. 2021 03; 10(5):1805-1814. PMID: 33560598.
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    7. Howell AV, Gebregziabher M, Thiers BH, Paulos CM, Wrangle JM, Hunt KJ, Wallace K. Immune checkpoint inhibitors retain effectiveness in older patients with cutaneous metastatic melanoma. J Geriatr Oncol. 2021 04; 12(3):394-401. PMID: 33132048.
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    8. Small J, Wallace K, Hill EG, Thiers BH, Leach BC, Alberg AJ. A cohort study of personal and family history of skin cancer in relation to all-cause and cancer-specific mortality. Cancer Causes Control. 2021 Jan; 32(1):75-82. PMID: 33123854.
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    9. Wallace K, Li H, Brazeal JG, Lewin DN, Sun S, Ba A, Paulos CM, Rachidi S, Li Z, Alekseyenko AV. Platelet and hemoglobin count at diagnosis are associated with survival in African American and Caucasian patients with colorectal cancer. Cancer Epidemiol. 2020 08; 67:101746. PMID: 32521488.
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    10. Ellison PL, Holman N, Wallace K, Cote GA, Elmunzer BJ, Brock AS. Multimodal intervention for avoiding inappropriate cessation of aspirin prior to outpatient endoscopy. Endosc Int Open. 2020 Jun; 8(6):E708-E716. PMID: 32490153.
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    11. Small J, Wallace K, Hill EG, Thiers BH, Leach BC, Alberg AJ. A cohort study of personal and family history of skin cancer in relation to future risk of non-cutaneous malignancies. Cancer Causes Control. 2019 Nov; 30(11):1213-1221. PMID: 31494748.
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    12. Hamidi B, Wallace K, Alekseyenko AV. MODIMA, a Method for Multivariate Omnibus Distance Mediation Analysis, Allows for Integration of Multivariate Exposure-Mediator-Response Relationships. Genes (Basel). 2019 07 11; 10(7). PMID: 31336807.
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    13. Hamidi B, Wallace K, Vasu C, Alekseyenko AV. W*d -test: robust distance-based multivariate analysis of variance Microbiome. 2019 04 01; 7(1):51. PMID: 30935409.
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    14. Mills AM, Peres LC, Meiss A, Ring KL, Modesitt SC, Abbott SE, Alberg AJ, Bandera EV, Barnholtz-Sloan J, Bondy ML, Cote ML, Funkhouser E, Moorman PG, Peters ES, Schwartz AG, Terry PD, Wallace K, Schildkraut JM. Targetable Immune Regulatory Molecule Expression in High-Grade Serous Ovarian Carcinomas in African American Women: A Study of PD-L1 and IDO in 112 Cases From the African American Cancer Epidemiology Study (AACES). Int J Gynecol Pathol. 2019 Mar; 38(2):157-170. PMID: 29485423.
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    15. Hildebrand JS, Wallace K, Graybill WS, Kelemen LE. Racial disparities in treatment and survival from ovarian cancer. Cancer Epidemiol. 2019 02; 58:77-82. PMID: 30528360.
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    16. Wallace K, Lewin DN, Sun S, Spiceland CM, Rockey DC, Alekseyenko AV, Wu JD, Baron JA, Alberg AJ, Hill EG. Tumor-Infiltrating Lymphocytes and Colorectal Cancer Survival in African American and Caucasian Patients. Cancer Epidemiol Biomarkers Prev. 2018 07; 27(7):755-761. PMID: 29769214.
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    17. Kelemen LE, Abbott S, Qin B, Peres LC, Moorman PG, Wallace K, Bandera EV, Barnholtz-Sloan JS, Bondy M, Cartmell K, Cote ML, Funkhouser E, Paddock LE, Peters ES, Schwartz AG, Terry P, Alberg AJ, Schildkraut JM. Cigarette smoking and the association with serous ovarian cancer in African American women: African American Cancer Epidemiology Study (AACES). Cancer Causes Control. 2017 Jul; 28(7):699-708. PMID: 28466107.
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    18. Wallace K, DeToma A, Lewin DN, Sun S, Rockey D, Britten CD, Wu JD, Ba A, Alberg AJ, Hill EG. Racial Differences in Stage IV Colorectal Cancer Survival in Younger and Older Patients. Clin Colorectal Cancer. 2017 09; 16(3):178-186. PMID: 28065664.
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    19. Erondu CO, Alberg AJ, Bandera EV, Barnholtz-Sloan J, Bondy M, Cote ML, Funkhouser E, Peters E, Schwartz AG, Terry PD, Wallace K, Akushevich L, Wang F, Crankshaw S, Berchuck A, Schildkraut JM, Moorman PG. The Association Between Body Mass Index and Presenting Symptoms in African American Women with Ovarian Cancer. J Womens Health (Larchmt). 2016 Jun; 25(6):571-8. PMID: 26886855.
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    20. Holman N, Wallace K, Moore JM, Brock AS. Open-Access Single Balloon Enteroscopy: A Tertiary Care Experience. South Med J. 2015 Dec; 108(12):739-43. PMID: 26630895.
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    21. Rachidi S, Wallace K, Wrangle JM, Day TA, Alberg AJ, Li Z. Neutrophil-to-lymphocyte ratio and overall survival in all sites of head and neck squamous cell carcinoma. Head Neck. 2016 04; 38 Suppl 1:E1068-74. PMID: 26040762.
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    22. Wallace K, Brandt HM, Bearden JD, Blankenship BF, Caldwell R, Dunn J, Hegedus P, Hoffman BJ, Marsh CH, Marsh WH, Melvin CL, Seabrook ME, Sterba RE, Stinson ML, Thibault A, Berger FG, Alberg AJ. Race and Prevalence of Large Bowel Polyps Among the Low-Income and Uninsured in South Carolina. Dig Dis Sci. 2016 Jan; 61(1):265-72. PMID: 26386856.
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    23. Onicescu G, Lawson A, Zhang J, Gebregziabher M, Wallace K, Eberth JM. Bayesian accelerated failure time model for space-time dependency in a geographically augmented survival model. Stat Methods Med Res. 2017 Oct; 26(5):2244-2256. PMID: 26220537.
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    24. Wallace K, Burke CA, Ahnen DJ, Barry EL, Bresalier RS, Saibil F, Baron JA. The association of age and race and the risk of large bowel polyps. Cancer Epidemiol Biomarkers Prev. 2015 Feb; 24(2):448-53. PMID: 25490989.
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    25. Rachidi S, Wallace K, Day TA, Alberg AJ, Li Z. Lower circulating platelet counts and antiplatelet therapy independently predict better outcomes in patients with head and neck squamous cell carcinoma. J Hematol Oncol. 2014 Sep 27; 7:65. PMID: 25260646.
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    26. Schildkraut JM, Alberg AJ, Bandera EV, Barnholtz-Sloan J, Bondy M, Cote ML, Funkhouser E, Peters E, Schwartz AG, Terry P, Wallace K, Akushevich L, Wang F, Crankshaw S, Moorman PG. A multi-center population-based case-control study of ovarian cancer in African-American women: the African American Cancer Epidemiology Study (AACES). BMC Cancer. 2014 Sep 22; 14:688. PMID: 25242549.
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    27. Wallace K, Sterba KR, Gore E, Lewin DN, Ford ME, Thomas MB, Alberg AJ. Prognostic factors in relation to racial disparity in advanced colorectal cancer survival. Clin Colorectal Cancer. 2013 Dec; 12(4):287-93. PMID: 24188687.
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    28. Brock AS, Wallace K, Romagnuolo J, Hoffman BJ. Patients' short-term knowledge of personal polyp history inadequate despite systematic notification of results after polypectomy. South Med J. 2013 Apr; 106(4):285-9. PMID: 23558419.
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    29. Alberg AJ, Wallace K, Silvestri GA, Brock MV. Invited commentary: the etiology of lung cancer in men compared with women. Am J Epidemiol. 2013 Apr 01; 177(7):613-6. PMID: 23425628.
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    30. Wallace K, Hill EG, Lewin DN, Williamson G, Oppenheimer S, Ford ME, Wargovich MJ, Berger FG, Bolick SW, Thomas MB, Alberg AJ. Racial disparities in advanced-stage colorectal cancer survival. Cancer Causes Control. 2013 Mar; 24(3):463-71. PMID: 23296454.
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    31. Sterba KR, Zapka J, Gore EI, Ford ME, Ford DW, Thomas M, Wallace K. Exploring dimensions of coping in advanced colorectal cancer: implications for patient-centered care. J Psychosoc Oncol. 2013; 31(5):517-39. PMID: 24010530.
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    32. Wallace K, Grau MV, Levine AJ, Shen L, Hamdan R, Chen X, Gui J, Haile RW, Barry EL, Ahnen D, McKeown-Eyssen G, Baron JA, Issa JP. Association between folate levels and CpG Island hypermethylation in normal colorectal mucosa. Cancer Prev Res (Phila). 2010 Dec; 3(12):1552-64. PMID: 21149331.
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    33. Wallace K, Grau MV, Ahnen D, Snover DC, Robertson DJ, Mahnke D, Gui J, Barry EL, Summers RW, McKeown-Eyssen G, Haile RW, Baron JA. The association of lifestyle and dietary factors with the risk for serrated polyps of the colorectum. Cancer Epidemiol Biomarkers Prev. 2009 Aug; 18(8):2310-7. PMID: 19661090.
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    34. Figueiredo JC, Grau MV, Wallace K, Levine AJ, Shen L, Hamdan R, Chen X, Bresalier RS, McKeown-Eyssen G, Haile RW, Baron JA, Issa JP. Global DNA hypomethylation (LINE-1) in the normal colon and lifestyle characteristics and dietary and genetic factors. Cancer Epidemiol Biomarkers Prev. 2009 Apr; 18(4):1041-9. PMID: 19336559.
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    35. Wallace K, Kelsey KT, Schned A, Morris JS, Andrew AS, Karagas MR. Selenium and risk of bladder cancer: a population-based case-control study. Cancer Prev Res (Phila). 2009 Jan; 2(1):70-3. PMID: 19139020.
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    36. Levine AJ, Wallace K, Tsang S, Haile RW, Saibil F, Ahnen D, Cole BF, Barry EL, Munroe DJ, Ali IU, Ueland P, Baron JA. MTHFR genotype and colorectal adenoma recurrence: data from a double-blind placebo-controlled clinical trial. Cancer Epidemiol Biomarkers Prev. 2008 Sep; 17(9):2409-15. PMID: 18768511.
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    37. Grau MV, Baron JA, Sandler RS, Wallace K, Haile RW, Church TR, Beck GJ, Summers RW, Barry EL, Cole BF, Snover DC, Rothstein R, Mandel JS. Prolonged effect of calcium supplementation on risk of colorectal adenomas in a randomized trial. J Natl Cancer Inst. 2007 Jan 17; 99(2):129-36. PMID: 17227996.
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    38. Barry EL, Baron JA, Grau MV, Wallace K, Haile RW. K-ras mutations in incident sporadic colorectal adenomas. Cancer. 2006 Mar 01; 106(5):1036-40. PMID: 16456810.
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    39. Wallace K, Baron JA, Karagas MR, Cole BF, Byers T, Beach MA, Pearson LH, Burke CA, Silverman WB, Sandler RS. The association of physical activity and body mass index with the risk of large bowel polyps. Cancer Epidemiol Biomarkers Prev. 2005 Sep; 14(9):2082-6. PMID: 16172213.
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    40. Baron JA, Beach M, Wallace K, Grau MV, Sandler RS, Mandel JS, Heber D, Greenberg ER. Risk of prostate cancer in a randomized clinical trial of calcium supplementation. Cancer Epidemiol Biomarkers Prev. 2005 Mar; 14(3):586-9. PMID: 15767334.
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    41. Jacobs ET, Jiang R, Alberts DS, Greenberg ER, Gunter EW, Karagas MR, Lanza E, Ratnasinghe L, Reid ME, Schatzkin A, Smith-Warner SA, Wallace K, Martínez ME. Selenium and colorectal adenoma: results of a pooled analysis. J Natl Cancer Inst. 2004 Nov 17; 96(22):1669-75. PMID: 15547179.
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    42. Wallace K, Baron JA, Cole BF, Sandler RS, Karagas MR, Beach MA, Haile RW, Burke CA, Pearson LH, Mandel JS, Rothstein R, Snover DC. Effect of calcium supplementation on the risk of large bowel polyps. J Natl Cancer Inst. 2004 Jun 16; 96(12):921-5. PMID: 15199111.
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    43. Wallace K, Byers T, Morris JS, Cole BF, Greenberg ER, Baron JA, Gudino A, Spate V, Karagas MR. Prediagnostic serum selenium concentration and the risk of recurrent colorectal adenoma: a nested case-control study. Cancer Epidemiol Biomarkers Prev. 2003 May; 12(5):464-7. PMID: 12750244.
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    44. Richman RA, Sheehe PR, Wallace K, Hyde JM, Coplan J. Olfactory performance during childhood. II. Developing a discrimination task for children. J Pediatr. 1995 Sep; 127(3):421-6. PMID: 7658273.
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    45. Richman RA, Wallace K, Sheehe PR. Assessment of an abbreviated odorant identification task for children: a rapid screening device for schools and clinics. Acta Paediatr. 1995 Apr; 84(4):434-7. PMID: 7795355.
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    46. Yi PN, Alexander CR, Fenn JO, Jarrett JH, Lung B, Wallace KM, Cho C. Swelling of multicellular spheroids induced by hyperthermia. Int J Hyperthermia. 1987 May-Jun; 3(3):217-33. PMID: 3116125.
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