Mark Alan Blenner

TitleAssistant Professor
InstitutionClemson University
DepartmentDepartment of Chemical and Biomolecular Engineering
Address125 Earle Hall
Clemson, South Carolina 29634
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Rodriguez-Ocasio E, Khalid A, Truka CJ, Blenner MA, Jarboe LR. Survey of nonconventional yeasts for lipid and hydrocarbon biotechnology. J Ind Microbiol Biotechnol. 2022 Jul 30; 49(4). PMID: 35348703.
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    2. Wang W, Blenner MA. Engineering heterologous enzyme secretion in Yarrowia lipolytica. Microb Cell Fact. 2022 Jul 04; 21(1):134. PMID: 35786380.
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    3. Ham RE, Smothers AR, King KL, Napolitano JM, Swann TJ, Pekarek LG, Blenner MA, Dean D. Efficient SARS-CoV-2 Quantitative Reverse Transcriptase PCR Saliva Diagnostic Strategy utilizing Open-Source Pipetting Robots. J Vis Exp. 2022 02 11; (180). PMID: 35225290.
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    4. Manglass LM, Wintenberg M, Vogel C, Blenner M, Martinez NE. Accumulation of radio-iron and plutonium, alone and in combination, inPseudomonas putidagrown in liquid cultures. J Radiol Prot. 2021 Nov 24; 41(4). PMID: 34644681.
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    5. Manglass L, Wintenberg M, Blenner M, Martinez N. Pu-239 Accumulation in E. Coli and P. Putida Grown in Liquid Cultures. Health Phys. 2021 11 01; 121(5):484-493. PMID: 34392252.
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    6. Darvishi F, Blenner M, Ledesma-Amaro R. Editorial: Synthetic Biology of Yeasts for the Production of Non-Native Chemicals. Front Bioeng Biotechnol. 2021; 9:730047. PMID: 34458244.
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    7. Yaguchi AL, Lee SJ, Blenner MA. Synthetic Biology towards Engineering Microbial Lignin Biotransformation. Trends Biotechnol. 2021 10; 39(10):1037-1064. PMID: 33712323.
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    8. Spagnuolo M, Blenner M. Gene Excision by Dual-Guide CRISPR-Cas9. Methods Mol Biol. 2021; 2307:85-94. PMID: 33847983.
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    9. Spagnuolo M, Blenner M. Simultaneous Gene Excision and Integration by Dual-Guide CRISPR-Cas9. Methods Mol Biol. 2021; 2307:69-83. PMID: 33847982.
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    10. Yang Z, Blenner M. Genome editing systems across yeast species. Curr Opin Biotechnol. 2020 12; 66:255-266. PMID: 33011454.
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    11. Czajka JJ, Okumus B, Koffas MA, Blenner M, Tang YJ. Mitigation of host cell mutations and regime shift during microbial fermentation: a perspective from flux memory. Curr Opin Biotechnol. 2020 12; 66:227-235. PMID: 33007633.
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    12. Molin WT, Yaguchi A, Blenner M, Saski CA. Autonomous replication sequences from the Amaranthus palmeri eccDNA replicon enable replication in yeast. BMC Res Notes. 2020 Jul 10; 13(1):330. PMID: 32650810.
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    13. Molin WT, Yaguchi A, Blenner M, Saski CA. The EccDNA Replicon: A Heritable, Extranuclear Vehicle That Enables Gene Amplification and Glyphosate Resistance in Amaranthus palmeri. Plant Cell. 2020 07; 32(7):2132-2140. PMID: 32327538.
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    14. Yaguchi A, Franaszek N, O'Neill K, Lee S, Sitepu I, Boundy-Mills K, Blenner M. Identification of oleaginous yeasts that metabolize aromatic compounds. J Ind Microbiol Biotechnol. 2020 Oct; 47(9-10):801-813. PMID: 32221720.
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    15. Iqbal S, Blenner M, Alexander-Bryant A, Larsen J. Polymersomes for Therapeutic Delivery of Protein and Nucleic Acid Macromolecules: From Design to Therapeutic Applications. Biomacromolecules. 2020 04 13; 21(4):1327-1350. PMID: 32078290.
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    16. Blenner M, van Pijkeren JP. Editorial overview: Food biotechnology. Curr Opin Biotechnol. 2020 02; 61:vi-viii. PMID: 32204852.
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    17. Ganesan V, Spagnuolo M, Agrawal A, Smith S, Gao D, Blenner M. Advances and opportunities in gene editing and gene regulation technology for Yarrowia lipolytica. Microb Cell Fact. 2019 Nov 29; 18(1):208. PMID: 31783869.
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    18. Schwartz C, Cheng JF, Evans R, Schwartz CA, Wagner JM, Anglin S, Beitz A, Pan W, Lonardi S, Blenner M, Alper HS, Yoshikuni Y, Wheeldon I. Validating genome-wide CRISPR-Cas9 function improves screening in the oleaginous yeast Yarrowia lipolytica. Metab Eng. 2019 09; 55:102-110. PMID: 31216436.
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    19. Spagnuolo M, Yaguchi A, Blenner M. Oleaginous yeast for biofuel and oleochemical production. Curr Opin Biotechnol. 2019 06; 57:73-81. PMID: 30875587.
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    20. Gao D, Smith S, Spagnuolo M, Rodriguez G, Blenner M. Dual CRISPR-Cas9 Cleavage Mediated Gene Excision and Targeted Integration in Yarrowia lipolytica. Biotechnol J. 2018 Sep; 13(9):e1700590. PMID: 29809313.
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    21. Spagnuolo M, Shabbir Hussain M, Gambill L, Blenner M. Alternative Substrate Metabolism in Yarrowia lipolytica. Front Microbiol. 2018; 9:1077. PMID: 29887845.
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    22. Brabender M, Hussain MS, Rodriguez G, Blenner MA. Urea and urine are a viable and cost-effective nitrogen source for Yarrowia lipolytica biomass and lipid accumulation. Appl Microbiol Biotechnol. 2018 Mar; 102(5):2313-2322. PMID: 29383430.
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    23. Yaguchi A, Spagnuolo M, Blenner M. Engineering yeast for utilization of alternative feedstocks. Curr Opin Biotechnol. 2018 10; 53:122-129. PMID: 29331920.
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    24. Yaguchi A, Robinson A, Mihealsick E, Blenner M. Metabolism of aromatics by Trichosporon oleaginosus while remaining oleaginous. Microb Cell Fact. 2017 Nov 17; 16(1):206. PMID: 29149902.
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    25. Shabbir Hussain M, Wheeldon I, Blenner MA. A Strong Hybrid Fatty Acid Inducible Transcriptional Sensor Built From Yarrowia lipolytica Upstream Activating and Regulatory Sequences. Biotechnol J. 2017 Oct; 12(10). PMID: 28731568.
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    26. Bulutoglu B, Dooley K, Szilvay G, Blenner M, Banta S. Catch and Release: Engineered Allosterically Regulated ß-Roll Peptides Enable On/Off Biomolecular Recognition. ACS Synth Biol. 2017 09 15; 6(9):1732-1741. PMID: 28520402.
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    27. Yaguchi A, Rives D, Blenner M. New kids on the block: emerging oleaginous yeast of biotechnological importance. AIMS Microbiol. 2017; 3(2):227-247. PMID: 31294158.
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    28. Schwartz C, Shabbir-Hussain M, Frogue K, Blenner M, Wheeldon I. Standardized Markerless Gene Integration for Pathway Engineering in Yarrowia lipolytica. ACS Synth Biol. 2017 03 17; 6(3):402-409. PMID: 27989123.
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    29. Rodriguez GM, Hussain MS, Gambill L, Gao D, Yaguchi A, Blenner M. Engineering xylose utilization in Yarrowia lipolytica by understanding its cryptic xylose pathway. Biotechnol Biofuels. 2016; 9:149. PMID: 27446238.
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    30. Schwartz CM, Hussain MS, Blenner M, Wheeldon I. Synthetic RNA Polymerase III Promoters Facilitate High-Efficiency CRISPR-Cas9-Mediated Genome Editing in Yarrowia lipolytica. ACS Synth Biol. 2016 Apr 15; 5(4):356-9. PMID: 26714206.
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    31. Shabbir Hussain M, Gambill L, Smith S, Blenner MA. Engineering Promoter Architecture in Oleaginous Yeast Yarrowia lipolytica. ACS Synth Biol. 2016 Mar 18; 5(3):213-23. PMID: 26635071.
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    32. Nedumpully-Govindan P, Li L, Alexov EG, Blenner MA, Ding F. Structural and energetic determinants of tyrosylprotein sulfotransferase sulfation specificity. Bioinformatics. 2014 Aug 15; 30(16):2302-9. PMID: 24794930.
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    33. Blenner MA, Dong X, Springer TA. Structural basis of regulation of von Willebrand factor binding to glycoprotein Ib. J Biol Chem. 2014 Feb 28; 289(9):5565-79. PMID: 24391089.
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    34. Shur O, Dooley K, Blenner M, Baltimore M, Banta S. A designed, phase changing RTX-based peptide for efficient bioseparations. Biotechniques. 2013 Apr; 54(4):197-8, 200, 202, 204, 206. PMID: 23581466.
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    35. Blenner MA, Shur O, Szilvay GR, Cropek DM, Banta S. Calcium-induced folding of a beta roll motif requires C-terminal entropic stabilization. J Mol Biol. 2010 Jul 09; 400(2):244-56. PMID: 20438736.
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    36. Szilvay GR, Blenner MA, Shur O, Cropek DM, Banta S. A FRET-based method for probing the conformational behavior of an intrinsically disordered repeat domain from Bordetella pertussis adenylate cyclase. Biochemistry. 2009 Dec 01; 48(47):11273-82. PMID: 19860484.
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    37. Blenner MA, Banta S. Characterization of the 4D5Flu single-chain antibody with a stimulus-responsive elastin-like peptide linker: a potential reporter of peptide linker conformation. Protein Sci. 2008 Mar; 17(3):527-36. PMID: 18218715.
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    38. Chockalingam K, Blenner M, Banta S. Design and application of stimulus-responsive peptide systems. Protein Eng Des Sel. 2007 Apr; 20(4):155-61. PMID: 17376876.
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    39. Orr RK, Hoehn JL, Col NF. The learning curve for sentinel node biopsy in breast cancer: practical considerations. Arch Surg. 1999 Jul; 134(7):764-7. PMID: 20420519.
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