William J.M. Hrushesky

Title
InstitutionMedical University of South Carolina
DepartmentPublic Health Sciences
Address
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    1. Demicheli R, Hrushesky WJM. Reimagining Cancer: Moving from the Cellular to the Tissue Level. Cancer Res. 2023 01 18; 83(2):173-180. PMID: 36264185.
      Citations:    Fields:    Translation:Humans
    2. Block KI, Gyllenhaal C, Grutsch JF, Block PB, Kazlausky T, Blask D, Carome E, Reynolds J, Huff DFQ, Hrushesky W, Block KI, Gyllenhaal C, Grutsch JF, Block PB, Kazlausky T, Blask D, Carome E, Reynolds J, Huff DFQ, Hrushesky W. Advanced cancer patients in a randomized clinical trial of night-simulating eyeglasses observed to have a normal 24-h circadian rhythm during chemotherapy. SAGE Open Med. 2022; 10:20503121221100137. PMID: 35646366; PMCID: PMC9134428.
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    3. Bennett CL, Focosi D, Socal MP, Bian JC, Nabhan C, Hrushesky WJ, Bennett AC, Schoen MW, Berger JR, Armitage JO, Bennett CL, Focosi D, Socal MP, Bian JC, Nabhan C, Hrushesky WJ, Bennett AC, Schoen MW, Berger JR, Armitage JO, Southern Network on Adverse Reactions. Progressive multifocal leukoencephalopathy in patients treated with rituximab: a 20-year review from the Southern Network on Adverse Reactions. Lancet Haematol. 2021 Aug; 8(8):e593-e604. PMID: 34329579.
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    4. Bennett CL, Nagai S, Bennett AC, Hoque S, Nabhan C, Schoen MW, Hrushesky WJ, Luminari S, Ray P, Yarnold PR, Witherspoon B, Riente J, Bobolts L, Brusk J, Tombleson R, Knopf K, Fishman M, Yang YT, Carson KR, Djulbegovic B, Restaino J, Armitage JO, Sartor OA, Bennett CL, Nagai S, Bennett AC, Hoque S, Nabhan C, Schoen MW, Hrushesky WJ, Luminari S, Ray P, Yarnold PR, Witherspoon B, Riente J, Bobolts L, Brusk J, Tombleson R, Knopf K, Fishman M, Yang YT, Carson KR, Djulbegovic B, Restaino J, Armitage JO, Sartor OA. The First 2?Years of Biosimilar Epoetin for Cancer and Chemotherapy-Induced Anemia in the U.S.: A Review from the Southern Network on Adverse Reactions. Oncologist. 2021 08; 26(8):e1418-e1426. PMID: 33586299; PMCID: PMC8342584.
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    5. Bennett CL, Hoque S, Olivieri N, Taylor MA, Aboulafia D, Lubaczewski C, Bennett AC, Vemula J, Schooley B, Witherspoon BJ, Godwin AC, Ray PS, Yarnold PR, Ausdenmoore HC, Fishman M, Herring G, Ventrone A, Aldaco J, Hrushesky WJ, Restaino J, Thomsen HS, Yarnold PR, Marx R, Migliorati C, Ruggiero S, Nabhan C, Carson KR, McKoy JM, Yang YT, Schoen MW, Knopf K, Martin L, Sartor O, Rosen S, Smith WK, Bennett CL, Hoque S, Olivieri N, Taylor MA, Aboulafia D, Lubaczewski C, Bennett AC, Vemula J, Schooley B, Witherspoon BJ, Godwin AC, Ray PS, Yarnold PR, Ausdenmoore HC, Fishman M, Herring G, Ventrone A, Aldaco J, Hrushesky WJ, Restaino J, Thomsen HS, Yarnold PR, Marx R, Migliorati C, Ruggiero S, Nabhan C, Carson KR, McKoy JM, Yang YT, Schoen MW, Knopf K, Martin L, Sartor O, Rosen S, Smith WK. Consequences to patients, clinicians, and manufacturers when very serious adverse drug reactions are identified (1997-2019): A qualitative analysis from the Southern Network on Adverse Reactions (SONAR). EClinicalMedicine. 2021 Jan; 31:100693. PMID: 33554084; PMCID: PMC7846671.
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    6. Bennett CL, Schoen MW, Hoque S, Witherspoon BJ, Aboulafia DM, Hwang CS, Ray P, Yarnold PR, Chen BK, Schooley B, Taylor MA, Wyatt MD, Hrushesky WJ, Yang YT, Bennett CL, Schoen MW, Hoque S, Witherspoon BJ, Aboulafia DM, Hwang CS, Ray P, Yarnold PR, Chen BK, Schooley B, Taylor MA, Wyatt MD, Hrushesky WJ, Yang YT. Improving oncology biosimilar launches in the EU, the USA, and Japan: an updated Policy Review from the Southern Network on Adverse Reactions. Lancet Oncol. 2020 12; 21(12):e575-e588. PMID: 33271114.
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    7. Demicheli R, Hrushesky W, Retsky M, Biganzoli E, Demicheli R, Hrushesky W, Retsky M, Biganzoli E. Interpreting Breast Cancer Survival Data by the Hazard Function: Remarkable Findings from Event Dynamics. Medicina (Kaunas). 2020 Sep 12; 56(9). PMID: 32932597; PMCID: PMC7559922.
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    8. Hoque S, Chen BJ, Schoen MW, Carson KR, Keller J, Witherspoon BJ, Knopf KB, Yang YT, Schooley B, Nabhan C, Sartor O, Yarnold PR, Ray P, Bobolts L, Hrushesky WJ, Dickson M, Bennett CL, Hoque S, Chen BJ, Schoen MW, Carson KR, Keller J, Witherspoon BJ, Knopf KB, Yang YT, Schooley B, Nabhan C, Sartor O, Yarnold PR, Ray P, Bobolts L, Hrushesky WJ, Dickson M, Bennett CL. End of an era of administering erythropoiesis stimulating agents among Veterans Administration cancer patients with chemotherapy-induced anemia. PLoS One. 2020; 15(6):e0234541. PMID: 32584835; PMCID: PMC7316310.
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    9. Retsky M, Demicheli R, Hrushesky W, James T, Rogers R, Baum M, Vaidya JS, Erhabor O, Forget P, Retsky M, Demicheli R, Hrushesky W, James T, Rogers R, Baum M, Vaidya JS, Erhabor O, Forget P. Breast cancer and the black swan. Ecancermedicalscience. 2020; 14:1050. PMID: 32565903; PMCID: PMC7289621.
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    10. Schoen MW, Hoque S, Witherspoon BJ, Schooley B, Sartor O, Yang YT, Yarnold PR, Knopf KB, Hrushesky WJM, Dickson M, Chen BJ, Nabhan C, Bennett CL, Schoen MW, Hoque S, Witherspoon BJ, Schooley B, Sartor O, Yang YT, Yarnold PR, Knopf KB, Hrushesky WJM, Dickson M, Chen BJ, Nabhan C, Bennett CL. End of an era for erythropoiesis-stimulating agents in oncology. Int J Cancer. 2020 05 15; 146(10):2829-2835. PMID: 32037527.
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    11. Bennett CL, Schooley B, Taylor MA, Witherspoon BJ, Godwin A, Vemula J, Ausdenmoore HC, Sartor O, Yang YT, Armitage JO, Hrushesky WJ, Restaino J, Thomsen HS, Yarnold PR, Young T, Knopf KB, Chen B, Bennett CL, Schooley B, Taylor MA, Witherspoon BJ, Godwin A, Vemula J, Ausdenmoore HC, Sartor O, Yang YT, Armitage JO, Hrushesky WJ, Restaino J, Thomsen HS, Yarnold PR, Young T, Knopf KB, Chen B. Caveat Medicus: Clinician experiences in publishing reports of serious oncology-associated adverse drug reactions. PLoS One. 2019; 14(7):e0219521. PMID: 31365527; PMCID: PMC6668902.
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    12. Chen B, Nagai S, Armitage JO, Witherspoon B, Nabhan C, Godwin AC, Yang YT, Kommalapati A, Tella SH, DeAngelis C, Raisch DW, Sartor O, Hrushesky WJ, Ray PS, Yarnold PR, Love BL, Norris LB, Knopf K, Bobolts L, Riente J, Luminari S, Kane RC, Hoque S, Bennett CL, Chen B, Nagai S, Armitage JO, Witherspoon B, Nabhan C, Godwin AC, Yang YT, Kommalapati A, Tella SH, DeAngelis C, Raisch DW, Sartor O, Hrushesky WJ, Ray PS, Yarnold PR, Love BL, Norris LB, Knopf K, Bobolts L, Riente J, Luminari S, Kane RC, Hoque S, Bennett CL. Regulatory and Clinical Experiences with Biosimilar Filgrastim in the U.S., the European Union, Japan, and Canada. Oncologist. 2019 04; 24(4):537-548. PMID: 30842244; PMCID: PMC6459242.
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    13. Sabol RA, Noxon V, Sartor O, Berger JR, Qureshi Z, Raisch DW, Norris LB, Yarnold PR, Georgantopoulos P, Hrushesky WJ, Bobolts L, Ray P, Lebby A, Kane RC, Bennett CL, Sabol RA, Noxon V, Sartor O, Berger JR, Qureshi Z, Raisch DW, Norris LB, Yarnold PR, Georgantopoulos P, Hrushesky WJ, Bobolts L, Ray P, Lebby A, Kane RC, Bennett CL. Melanoma complicating treatment with natalizumab for multiple sclerosis: A report from the Southern Network on Adverse Reactions (SONAR). Cancer Med. 2017 Jul; 6(7):1541-1551. PMID: 28635055; PMCID: PMC5504343.
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    14. Noxon V, Knopf KB, Norris LB, Chen B, Yang YT, Qureshi ZP, Hrushesky W, Lebby AA, Schooley B, Hikmet N, Dickson M, Thamer M, Cotter D, Yarnold PR, Bennett CL, Noxon V, Knopf KB, Norris LB, Chen B, Yang YT, Qureshi ZP, Hrushesky W, Lebby AA, Schooley B, Hikmet N, Dickson M, Thamer M, Cotter D, Yarnold PR, Bennett CL. Tale of Two Erythropoiesis-Stimulating Agents: Utilization, Dosing, Litigation, and Costs of Darbepoetin and Epoetin Among South Carolina Medicaid-Covered Patients With Cancer and Chemotherapy-Induced Anemia. J Oncol Pract. 2017 06; 13(6):e562-e573. PMID: 28504901; PMCID: PMC6366245.
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    15. Knopf K, Baum M, Shimp WS, Bennett CL, Faith D, Fishman ML, Hrushesky WJ, Knopf K, Baum M, Shimp WS, Bennett CL, Faith D, Fishman ML, Hrushesky WJ. Interpretation of surrogate endpoints in the era of the 21st Century Cures Act. BMJ. 2016 Dec 30; 355:i6286. PMID: 28039123.
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    16. Yang YT, Nagai S, Chen BK, Qureshi ZP, Lebby AA, Kessler S, Georgantopoulos P, Raisch DW, Sartor O, Hermanson T, Kane RC, Hrushesky WJ, Riente JJ, Norris LB, Bobolts LR, Armitage JO, Bennett CL, Yang YT, Nagai S, Chen BK, Qureshi ZP, Lebby AA, Kessler S, Georgantopoulos P, Raisch DW, Sartor O, Hermanson T, Kane RC, Hrushesky WJ, Riente JJ, Norris LB, Bobolts LR, Armitage JO, Bennett CL. Generic oncology drugs: are they all safe? Lancet Oncol. 2016 Nov; 17(11):e493-e501. PMID: 27819247.
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    17. Bennett CL, Berger JR, Sartor O, Carson KR, Hrushesky WJ, Georgantopoulos P, Raisch DW, Norris LB, Armitage JO, Bennett CL, Berger JR, Sartor O, Carson KR, Hrushesky WJ, Georgantopoulos P, Raisch DW, Norris LB, Armitage JO. Progressive multi-focal leucoencephalopathy among ibrutinib-treated persons with chronic lymphocytic leukaemia. Br J Haematol. 2018 01; 180(2):301-304. PMID: 27649938.
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    18. Qureshi Z, Hrushesky W, Bennett C, Qureshi Z, Hrushesky W, Bennett C. Editorial Comment. Urology. 2016 07; 93:74-5. PMID: 27179946.
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    19. Demicheli R, Quiton DF, Fornili M, Hrushesky WJ, Demicheli R, Quiton DF, Fornili M, Hrushesky WJ. Cancer as a changed tissue's way of life (when to treat, when to watch and when to think). Future Oncol. 2016 Mar; 12(5):647-57. PMID: 26880385.
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    20. Bennett CL, Lai SY, Sartor O, Georgantopoulos P, Hrushesky WJ, Henke M, Armitage JO, Bennett CL, Lai SY, Sartor O, Georgantopoulos P, Hrushesky WJ, Henke M, Armitage JO. Consensus on the Existence of Functional Erythropoietin Receptors on Cancer Cells. JAMA Oncol. 2016 Jan; 2(1):134-6. PMID: 26606114.
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    21. Hermanson TT, Hrushesky WJ, Knopf KB, Bennett CL, Hermanson TT, Hrushesky WJ, Knopf KB, Bennett CL. Adding Bevacizumab to the Treatment of Patients With Non-Small-Cell Lung Cancer: Caveat Emptor. J Oncol Pract. 2015 Sep; 11(5):363-4. PMID: 26243648.
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    22. Hrushesky W, Rich IN, Hrushesky W, Rich IN. Measuring stem cell circadian rhythm. Methods Mol Biol. 2015; 1235:81-95. PMID: 25388388.
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    23. Bennett CL, Chen B, Hermanson T, Wyatt MD, Schulz RM, Georgantopoulos P, Kessler S, Raisch DW, Qureshi ZP, Lu ZK, Love BL, Noxon V, Bobolts L, Armitage M, Bian J, Ray P, Ablin RJ, Hrushesky WJ, Macdougall IC, Sartor O, Armitage JO, Bennett CL, Chen B, Hermanson T, Wyatt MD, Schulz RM, Georgantopoulos P, Kessler S, Raisch DW, Qureshi ZP, Lu ZK, Love BL, Noxon V, Bobolts L, Armitage M, Bian J, Ray P, Ablin RJ, Hrushesky WJ, Macdougall IC, Sartor O, Armitage JO. Regulatory and clinical considerations for biosimilar oncology drugs. Lancet Oncol. 2014 Dec; 15(13):e594-e605. PMID: 25456378; PMCID: PMC4404762.
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    24. Orr RK, Hoehn JL, Col NF, Retsky M, Demicheli R, Hrushesky WJ, Forget P, De Kock M, Gukas I, Rogers RA, Baum M, Sukhatme V, Vaidya JS. Reduction of breast cancer relapses with perioperative non-steroidal anti-inflammatory drugs: new findings and a review. Curr Med Chem. 2013; 20(33):4163-76. PMID: 23992307; PMCID: PMC3831877.
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    25. Retsky M, Demicheli R, Hrushesky WJ, Forget P, De Kock M, Gukas I, Rogers RA, Baum M, Pachmann K, Vaidya JS, Retsky M, Demicheli R, Hrushesky WJ, Forget P, De Kock M, Gukas I, Rogers RA, Baum M, Pachmann K, Vaidya JS. Promising development from translational or perhaps anti-translational research in breast cancer. Clin Transl Med. 2012 Aug 28; 1(1):17. PMID: 23369485; PMCID: PMC3560986.
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    26. Fishman M, Shimp W, Krook J, Kumar A, Hrushesky WJ, Fishman M, Shimp W, Krook J, Kumar A, Hrushesky WJ. Correspondence. J Natl Compr Canc Netw. 2012 Jul 01; 10(7):xxxvii. PMID: 22773804.
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    27. Retsky M, Rogers R, Demicheli R, Hrushesky WJ, Gukas I, Vaidya JS, Baum M, Forget P, Dekock M, Pachmann K, Retsky M, Rogers R, Demicheli R, Hrushesky WJ, Gukas I, Vaidya JS, Baum M, Forget P, Dekock M, Pachmann K. NSAID analgesic ketorolac used perioperatively may suppress early breast cancer relapse: particular relevance to triple negative subgroup. Breast Cancer Res Treat. 2012 Jul; 134(2):881-8. PMID: 22622810.
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    28. Fishman ML, Kumar A, Davis S, Shimp W, Hrushesky WJ, Fishman ML, Kumar A, Davis S, Shimp W, Hrushesky WJ. Guideline-based peer-to-peer consultation optimizes pegfilgrastim use with no adverse clinical consequences. Am J Manag Care. 2012 05 01; 18(5):e168-72. PMID: 22694110.
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    29. Fishman ML, Kumar A, Davis S, Shimp W, Hrushesky WJ, Fishman ML, Kumar A, Davis S, Shimp W, Hrushesky WJ. Guideline-Based Peer-to-Peer Consultation Optimizes Pegfilgrastim Use With No Adverse Clinical Consequences. J Oncol Pract. 2012 May; 8(3 Suppl):e14s-7s. PMID: 22942828; PMCID: PMC3348596.
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    30. Hrushesky W, Kumar A, Davis S, Fishman M, Hrushesky W, Kumar A, Davis S, Fishman M. Countering the Misincentivization of Cancer Medicine by Real-Time Personal Professional Education. J Oncol Pract. 2012 Mar; 8(2):70. PMID: 29447096; PMCID: PMC3457828.
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    31. Grutsch JF, Ferrans C, Wood PA, Du-Quiton J, Quiton DF, Reynolds JL, Ansell CM, Oh EY, Daehler MA, Levin RD, Braun DP, Gupta D, Lis CG, Hrushesky WJ, Grutsch JF, Ferrans C, Wood PA, Du-Quiton J, Quiton DF, Reynolds JL, Ansell CM, Oh EY, Daehler MA, Levin RD, Braun DP, Gupta D, Lis CG, Hrushesky WJ. The association of quality of life with potentially remediable disruptions of circadian sleep/activity rhythms in patients with advanced lung cancer. BMC Cancer. 2011 May 23; 11:193. PMID: 21605390; PMCID: PMC3114794.
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    32. Grutsch JF, Wood PA, Du-Quiton J, Reynolds JL, Lis CG, Levin RD, Ann Daehler M, Gupta D, Quiton DF, Hrushesky WJ, Grutsch JF, Wood PA, Du-Quiton J, Reynolds JL, Lis CG, Levin RD, Ann Daehler M, Gupta D, Quiton DF, Hrushesky WJ. Validation of actigraphy to assess circadian organization and sleep quality in patients with advanced lung cancer. J Circadian Rhythms. 2011 May 18; 9:4. PMID: 21592392; PMCID: PMC3113323.
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    33. Hrushesky WJ, Sothern RB, Du-Quiton J, Quiton DF, Rietveld W, Boon ME, Hrushesky WJ, Sothern RB, Du-Quiton J, Quiton DF, Rietveld W, Boon ME. Sunspot dynamics are reflected in human physiology and pathophysiology. Astrobiology. 2011 Mar; 11(2):93-103. PMID: 21391821; PMCID: PMC3063695.
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    34. Orr RK, Hoehn JL, Col NF, Demicheli R, Ardoino I, Boracchi P, Coradini D, Agresti R, Ferraris C, Gennaro M, Hrushesky WJ, Biganzoli E. Recurrence and mortality according to estrogen receptor status for breast cancer patients undergoing conservative surgery. Ipsilateral breast tumour recurrence dynamics provides clues for tumour biology within the residual breast. BMC Cancer. 2010 Nov 30; 10:656. PMID: 21118508; PMCID: PMC3002930.
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    35. Oh EY, Yang X, Friedman A, Ansell CM, Du-Quiton J, Quiton DF, Wood PA, Hrushesky WJ, Oh EY, Yang X, Friedman A, Ansell CM, Du-Quiton J, Quiton DF, Wood PA, Hrushesky WJ. Circadian transcription profile of mouse breast cancer under light-dark and dark-dark conditions. Cancer Genomics Proteomics. 2010 Nov-Dec; 7(6):311-22. PMID: 21156964.
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    36. Orr RK, Hoehn JL, Col NF, Lee H, Arnouk H, Sripathi S, Chen P, Zhang R, Bartoli M, Hunt RC, Hrushesky WJ, Chung H, Lee SH, Jahng WJ. Prohibitin as an oxidative stress biomarker in the eye. Int J Biol Macromol. 2010 Dec 01; 47(5):685-90. PMID: 20832420; PMCID: PMC5155449.
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    37. Lee H, Chung H, Arnouk H, Lamoke F, Hunt RC, Hrushesky WJ, Wood PA, Lee SH, Jahng WJ, Lee H, Chung H, Arnouk H, Lamoke F, Hunt RC, Hrushesky WJ, Wood PA, Lee SH, Jahng WJ. Cleavage of the retinal pigment epithelium-specific protein RPE65 under oxidative stress. Int J Biol Macromol. 2010 Aug 01; 47(2):104-8. PMID: 20510285; PMCID: PMC5158184.
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    38. Zhang R, Hrushesky WJ, Wood PA, Lee SH, Hunt RC, Jahng WJ, Zhang R, Hrushesky WJ, Wood PA, Lee SH, Hunt RC, Jahng WJ. Melatonin reprogrammes proteomic profile in light-exposed retina in vivo. Int J Biol Macromol. 2010 Aug 01; 47(2):255-60. PMID: 20434483; PMCID: PMC5292325.
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    39. Retsky M, Demicheli R, Hrushesky W, Baum M, Gukas I, Retsky M, Demicheli R, Hrushesky W, Baum M, Gukas I. Surgery triggers outgrowth of latent distant disease in breast cancer: an inconvenient truth? Cancers (Basel). 2010 Mar 30; 2(2):305-37. PMID: 24281072; PMCID: PMC3835080.
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    40. Oh EY, Ansell C, Nawaz H, Yang CH, Wood PA, Hrushesky WJ, Oh EY, Ansell C, Nawaz H, Yang CH, Wood PA, Hrushesky WJ. Global breast cancer seasonality. Breast Cancer Res Treat. 2010 Aug; 123(1):233-43. PMID: 20130986.
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    41. Du-Quiton J, Wood PA, Burch JB, Grutsch JF, Gupta D, Tyer K, Lis CG, Levin RD, Quiton DF, Reynolds JL, Hrushesky WJ, Du-Quiton J, Wood PA, Burch JB, Grutsch JF, Gupta D, Tyer K, Lis CG, Levin RD, Quiton DF, Reynolds JL, Hrushesky WJ. Actigraphic assessment of daily sleep-activity pattern abnormalities reflects self-assessed depression and anxiety in outpatients with advanced non-small cell lung cancer. Psychooncology. 2010 Feb; 19(2):180-9. PMID: 19199317.
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    42. Yang F, Yang X, Jiang H, Bulkhaults P, Wood P, Hrushesky W, Wang G, Yang F, Yang X, Jiang H, Bulkhaults P, Wood P, Hrushesky W, Wang G. Dielectrophoretic separation of colorectal cancer cells. Biomicrofluidics. 2010 Jan 12; 4(1):13204. PMID: 20644667; PMCID: PMC2905264.
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    43. Nemunaitis J, Clayman G, Agarwala SS, Hrushesky W, Wells JR, Moore C, Hamm J, Yoo G, Baselga J, Murphy BA, Menander KA, Licato LL, Chada S, Gibbons RD, Olivier M, Hainaut P, Roth JA, Sobol RE, Goodwin WJ, Nemunaitis J, Clayman G, Agarwala SS, Hrushesky W, Wells JR, Moore C, Hamm J, Yoo G, Baselga J, Murphy BA, Menander KA, Licato LL, Chada S, Gibbons RD, Olivier M, Hainaut P, Roth JA, Sobol RE, Goodwin WJ. Biomarkers Predict p53 Gene Therapy Efficacy in Recurrent Squamous Cell Carcinoma of the Head and Neck. Clin Cancer Res. 2009 Dec 15; 15(24):7719-7725. PMID: 19996201.
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    44. Yang X, Wood PA, Hrushesky WJ, Yang X, Wood PA, Hrushesky WJ. Mammalian TIMELESS is required for ATM-dependent CHK2 activation and G2/M checkpoint control. J Biol Chem. 2010 Jan 29; 285(5):3030-4. PMID: 19996108; PMCID: PMC2823431.
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    45. Block KI, Hrushesky W, Blask D, Block KI, Hrushesky W, Blask D. In this issue: circadian disruption and cancer. Integr Cancer Ther. 2009 Dec; 8(4):295-7. PMID: 20042407.
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    46. Wood PA, Yang X, Hrushesky WJ, Wood PA, Yang X, Hrushesky WJ. Clock genes and cancer. Integr Cancer Ther. 2009 Dec; 8(4):303-8. PMID: 20042409.
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    47. Guess J, Burch JB, Ogoussan K, Armstead CA, Zhang H, Wagner S, Hebert JR, Wood P, Youngstedt SD, Hofseth LJ, Singh UP, Xie D, Hrushesky WJ, Guess J, Burch JB, Ogoussan K, Armstead CA, Zhang H, Wagner S, Hebert JR, Wood P, Youngstedt SD, Hofseth LJ, Singh UP, Xie D, Hrushesky WJ. Circadian disruption, Per3, and human cytokine secretion. Integr Cancer Ther. 2009 Dec; 8(4):329-36. PMID: 19926609; PMCID: PMC2959170.
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    48. Hrushesky WJ, Grutsch J, Wood P, Yang X, Oh EY, Ansell C, Kidder S, Ferrans C, Quiton DF, Reynolds J, Du-Quiton J, Levin R, Lis C, Braun D, Hrushesky WJ, Grutsch J, Wood P, Yang X, Oh EY, Ansell C, Kidder S, Ferrans C, Quiton DF, Reynolds J, Du-Quiton J, Levin R, Lis C, Braun D. Circadian clock manipulation for cancer prevention and control and the relief of cancer symptoms. Integr Cancer Ther. 2009 Dec; 8(4):387-97. PMID: 19926611.
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    49. Yang X, Wood PA, Ansell C, Hrushesky WJ, Yang X, Wood PA, Ansell C, Hrushesky WJ. Circadian time-dependent tumor suppressor function of period genes. Integr Cancer Ther. 2009 Dec; 8(4):309-16. PMID: 19926612.
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    50. Oh EY, Wood PA, Yang X, Hrushesky WJ, Oh EY, Wood PA, Yang X, Hrushesky WJ. Discovery of candidate genes and pathways that may help explain fertility cycle stage dependent post-resection breast cancer outcome. Breast Cancer Res Treat. 2009 Nov; 118(2):345-59. PMID: 19051007.
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    51. Yang X, Wood PA, Ansell CM, Quiton DF, Oh EY, Du-Quiton J, Hrushesky WJ, Yang X, Wood PA, Ansell CM, Quiton DF, Oh EY, Du-Quiton J, Hrushesky WJ. The circadian clock gene Per1 suppresses cancer cell proliferation and tumor growth at specific times of day. Chronobiol Int. 2009 Oct; 26(7):1323-39. PMID: 19916834.
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    52. Singletary J, Wood PA, Du-Quiton J, Wang S, Yang X, Vishnoi S, Hrushesky WJ, Singletary J, Wood PA, Du-Quiton J, Wang S, Yang X, Vishnoi S, Hrushesky WJ. Imaging multidimensional therapeutically relevant circadian relationships. Int J Biomed Imaging. 2009; 2009:231539. PMID: 19688113; PMCID: PMC2727657.
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    53. Chung H, Lee H, Lamoke F, Hrushesky WJ, Wood PA, Jahng WJ, Chung H, Lee H, Lamoke F, Hrushesky WJ, Wood PA, Jahng WJ. Neuroprotective role of erythropoietin by antiapoptosis in the retina. J Neurosci Res. 2009 Aug 01; 87(10):2365-74. PMID: 19301424; PMCID: PMC5161804.
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    54. Retsky MW, Hrushesky WJ, Gukas ID, Retsky MW, Hrushesky WJ, Gukas ID. Hypothesis: primary antiangiogenic method proposed to treat early stage breast cancer. BMC Cancer. 2009 Jan 08; 9:7. PMID: 19133151; PMCID: PMC2633344.
      Citations:    
    55. Yang X, Wood PA, Ansell CM, Ohmori M, Oh EY, Xiong Y, Berger FG, Peña MM, Hrushesky WJ, Yang X, Wood PA, Ansell CM, Ohmori M, Oh EY, Xiong Y, Berger FG, Pe?a MM, Hrushesky WJ. Beta-catenin induces beta-TrCP-mediated PER2 degradation altering circadian clock gene expression in intestinal mucosa of ApcMin/+ mice. J Biochem. 2009 Mar; 145(3):289-97. PMID: 19106159.
      Citations:    
    56. Wood PA, Yang X, Taber A, Oh EY, Ansell C, Ayers SE, Al-Assaad Z, Carnevale K, Berger FG, Peña MM, Hrushesky WJ, Wood PA, Yang X, Taber A, Oh EY, Ansell C, Ayers SE, Al-Assaad Z, Carnevale K, Berger FG, Pe?a MM, Hrushesky WJ. Period 2 mutation accelerates ApcMin/+ tumorigenesis. Mol Cancer Res. 2008 Nov; 6(11):1786-93. PMID: 19010825; PMCID: PMC4136553.
      Citations:    
    57. Yang X, Wood PA, Oh EY, Du-Quiton J, Ansell CM, Hrushesky WJ, Yang X, Wood PA, Oh EY, Du-Quiton J, Ansell CM, Hrushesky WJ. Down regulation of circadian clock gene Period 2 accelerates breast cancer growth by altering its daily growth rhythm. Breast Cancer Res Treat. 2009 Sep; 117(2):423-31. PMID: 18651214.
      Citations:    
    58. Retsky MW, Demicheli R, Hrushesky WJ, Baum M, Gukas ID, Retsky MW, Demicheli R, Hrushesky WJ, Baum M, Gukas ID. Dormancy and surgery-driven escape from dormancy help explain some clinical features of breast cancer. APMIS. 2008 Jul-Aug; 116(7-8):730-41. PMID: 18834415.
      Citations:    
    59. Demicheli R, Retsky MW, Hrushesky WJ, Baum M, Gukas ID, Demicheli R, Retsky MW, Hrushesky WJ, Baum M, Gukas ID. The effects of surgery on tumor growth: a century of investigations. Ann Oncol. 2008 Nov; 19(11):1821-8. PMID: 18550576.
      Citations:    
    60. Ramanathan RK, Bjarnason GA, Bernard SA, Desimone P, Braich T, Evars JP, Hrushesky WJ, Jolivet J, Ramanathan RK, Bjarnason GA, Bernard SA, Desimone P, Braich T, Evars JP, Hrushesky WJ, Jolivet J. A four-arm, randomized, multicenter phase II trial of oxaliplatin combined with varying schedules of 5-fluorouracil as first-line therapy in previously untreated advanced colorectal cancer. Clin Colorectal Cancer. 2008 Mar; 7(2):134-9. PMID: 18501073.
      Citations:    
    61. Demicheli R, Retsky MW, Hrushesky WJ, Baum M, Demicheli R, Retsky MW, Hrushesky WJ, Baum M. Tumor dormancy and surgery-driven interruption of dormancy in breast cancer: learning from failures. Nat Clin Pract Oncol. 2007 Dec; 4(12):699-710. PMID: 18037874.
      Citations:    
    62. Demicheli R, Retsky MW, Hrushesky WJ, Baum M, Gukas ID, Jatoi I, Demicheli R, Retsky MW, Hrushesky WJ, Baum M, Gukas ID, Jatoi I. Racial disparities in breast cancer outcome: insights into host-tumor interactions. Cancer. 2007 Nov 01; 110(9):1880-8. PMID: 17876835.
      Citations:    
    63. Oh EY, Wood PA, Du-Quiton J, Hrushesky WJ, Oh EY, Wood PA, Du-Quiton J, Hrushesky WJ. Seasonal modulation of post-resection breast cancer metastasis. Breast Cancer Res Treat. 2008 Sep; 111(2):219-28. PMID: 17934872.
      Citations:    
    64. Hrushesky WJ, Retsky M, Baum M, Demicheli R, Hrushesky WJ, Retsky M, Baum M, Demicheli R. Re: Prognostic value of Ki67 expression after short-term presurgical endocrine therapy for primary breast cancer. J Natl Cancer Inst. 2007 Jul 04; 99(13):1053; author reply 1053-4. PMID: 17596578.
      Citations:    
    65. Berk L, Berkey B, Rich T, Hrushesky W, Blask D, Gallagher M, Kudrimoti M, McGarry RC, Suh J, Mehta M, Berk L, Berkey B, Rich T, Hrushesky W, Blask D, Gallagher M, Kudrimoti M, McGarry RC, Suh J, Mehta M. Randomized phase II trial of high-dose melatonin and radiation therapy for RPA class 2 patients with brain metastases (RTOG 0119). Int J Radiat Oncol Biol Phys. 2007 Jul 01; 68(3):852-7. PMID: 17418968; PMCID: PMC2709786.
      Citations:    
    66. Demicheli R, Hrushesky WJ, Retsky MW, Bonadonna G, Valagussa P, Demicheli R, Hrushesky WJ, Retsky MW, Bonadonna G, Valagussa P. Comment to "Effect of primary tumor extirpation in breast cancer patients who present with stage IV disease and intact primary tumor" by G V Babiera, R Rao, L Feng, F Meric-Bernstam, H M Kuerer, S E Singletary, K K Hunt, M I Ross, K M Gwyn, B W Feig, F C Ames, G N Horthobagyi. Ann Surg Oncol 2006;13:776-782. Ann Surg Oncol. 2007 Apr; 14(4):1519-20. PMID: 17225978.
      Citations:    
    67. Retsky MW, Demicheli R, Gukas ID, Hrushesky WJ, Retsky MW, Demicheli R, Gukas ID, Hrushesky WJ. Enhanced surgery-induced angiogenesis among premenopausal women might partially explain excess breast cancer mortality of blacks compared to whites: an hypothesis. Int J Surg. 2007 Oct; 5(5):300-4. PMID: 17933694.
      Citations:    
    68. Demicheli R, Biganzoli E, Boracchi P, Greco M, Hrushesky WJ, Retsky MW, Demicheli R, Biganzoli E, Boracchi P, Greco M, Hrushesky WJ, Retsky MW. Allometric scaling law questions the traditional mechanical model for axillary lymph node involvement in breast cancer. J Clin Oncol. 2006 Sep 20; 24(27):4391-6. PMID: 16926222.
      Citations:    
    69. Wood PA, Du-Quiton J, You S, Hrushesky WJ, Wood PA, Du-Quiton J, You S, Hrushesky WJ. Circadian clock coordinates cancer cell cycle progression, thymidylate synthase, and 5-fluorouracil therapeutic index. Mol Cancer Ther. 2006 Aug; 5(8):2023-33. PMID: 16928823.
      Citations:    
    70. Kanabrocki EL, Hermida RC, Torossov M, Haseman MB, Bettis K, Young RM, Mathew JP, Potkul R, Hrushesky WJ, Kanabrocki EL, Hermida RC, Torossov M, Haseman MB, Bettis K, Young RM, Mathew JP, Potkul R, Hrushesky WJ. Chronotherapy of ovarian cancer: effect on blood variables and serum cytokines. A case report. Clin Ter. 2006 Jul-Aug; 157(4):349-54. PMID: 17051973.
      Citations:    
    71. You S, Ohmori M, Peña MM, Nassri B, Quiton J, Al-Assad ZA, Liu L, Wood PA, Berger SH, Liu Z, Wyatt MD, Price RL, Berger FG, Hrushesky WJ, You S, Ohmori M, Pe?a MM, Nassri B, Quiton J, Al-Assad ZA, Liu L, Wood PA, Berger SH, Liu Z, Wyatt MD, Price RL, Berger FG, Hrushesky WJ. Developmental abnormalities in multiple proliferative tissues of Apc(Min/+) mice. Int J Exp Pathol. 2006 Jun; 87(3):227-36. PMID: 16709231; PMCID: PMC2517368.
      Citations:    
    72. Demicheli R, Bonadonna G, Greco M, Hrushesky WJ, Moliterni A, Retsky MW, Valagussa P, Zambetti M, Demicheli R, Bonadonna G, Greco M, Hrushesky WJ, Moliterni A, Retsky MW, Valagussa P, Zambetti M. Comment to Anderson WF, Jatoi I, Devesa SS: distinct breast cancer incidence and prognostic patterns in the NCI'S SEER program: suggesting a possible link between etiology and outcome. Breast Cancer Res Treat 90:127-137, 2005. Breast Cancer Res Treat. 2006 Jun; 97(3):341-3. PMID: 16791490.
      Citations:    
    73. Retsky MW, Demicheli R, Hrushesky WJ, Retsky MW, Demicheli R, Hrushesky WJ. Screening and breast cancer. N Engl J Med. 2006 Feb 16; 354(7):767-9; author reply 767-9. PMID: 16482676.
      Citations:    
    74. Retsky MW, Hrushesky W, Baum M, Retsky MW, Hrushesky W, Baum M. Sociodemographic determinants of cancer treatment health literacy. Cancer. 2006 Feb 01; 106(3):726-7; author reply 727. PMID: 16369990.
      Citations:    
    75. Halberg F, Cornélissen G, Ulmer W, Blank M, Hrushesky W, Wood P, Singh RK, Wang Z, Halberg F, Corn?lissen G, Ulmer W, Blank M, Hrushesky W, Wood P, Singh RK, Wang Z. Cancer chronomics III. Chronomics for cancer, aging, melatonin and experimental therapeutics researchers. J Exp Ther Oncol. 2006; 6(1):73-84. PMID: 17228527; PMCID: PMC2742383.
      Citations:    
    76. Retsky M, Demicheli R, Hrushesky WJ, Retsky M, Demicheli R, Hrushesky WJ. Authors respond to controversy surrounding breast cancer study. Int J Surg. 2005; 3(4):235-9. PMID: 17462290.
      Citations:    
    77. Levin RD, Daehler MA, Grutsch JF, Quiton J, Lis CG, Peterson C, Gupta D, Watson K, Layer D, Huff-Adams S, Desai B, Sharma P, Wallam M, Delioukina M, Ball P, Bryant M, Ashford M, Copeland D, Ohmori M, Wood PA, Hrushesky WJ, Levin RD, Daehler MA, Grutsch JF, Quiton J, Lis CG, Peterson C, Gupta D, Watson K, Layer D, Huff-Adams S, Desai B, Sharma P, Wallam M, Delioukina M, Ball P, Bryant M, Ashford M, Copeland D, Ohmori M, Wood PA, Hrushesky WJ. Circadian function in patients with advanced non-small-cell lung cancer. Br J Cancer. 2005 Nov 28; 93(11):1202-8. PMID: 16265345; PMCID: PMC2361523.
      Citations:    
    78. Hrushesky WJ, Sothern RB, Rietveld WJ, Du-Quiton J, Boon ME, Hrushesky WJ, Sothern RB, Rietveld WJ, Du-Quiton J, Boon ME. Sun exposure, sexual behavior and uterine cervical human papilloma virus. Int J Biometeorol. 2006 Jan; 50(3):167-73. PMID: 16208499.
      Citations:    
    79. Retsky M, Demicheli R, Hrushesky WJ, Retsky M, Demicheli R, Hrushesky WJ. Does surgery induce angiogenesis in breast cancer? Indirect evidence from relapse pattern and mammography paradox. Int J Surg. 2005; 3(3):179-87. PMID: 17462282.
      Citations:    
    80. Demicheli R, Bonadonna G, Valagussa P, Retsky MW, Hrushesky WJ, Baum M, Demicheli R, Bonadonna G, Valagussa P, Retsky MW, Hrushesky WJ, Baum M. Comment to Jatoi et al. report. Breast Cancer Res Treat. 2005 Sep; 93(1):1-2. PMID: 16184452.
      Citations:    
    81. Hrushesky WJ, Sothern RB, Rietveld WJ, Du Quiton J, Boon ME, Hrushesky WJ, Sothern RB, Rietveld WJ, Du Quiton J, Boon ME. Season, sun, sex, and cervical cancer. Cancer Epidemiol Biomarkers Prev. 2005 Aug; 14(8):1940-7. PMID: 16103441.
      Citations:    
    82. Wood PA, Bove K, You S, Chambers A, Hrushesky WJ, Wood PA, Bove K, You S, Chambers A, Hrushesky WJ. Cancer growth and spread are saltatory and phase-locked to the reproductive cycle through mediators of angiogenesis. Mol Cancer Ther. 2005 Jul; 4(7):1065-75. PMID: 16020664.
      Citations:    
    83. Demicheli R, Miceli R, Moliterni A, Zambetti M, Hrushesky WJ, Retsky MW, Valagussa P, Bonadonna G, Demicheli R, Miceli R, Moliterni A, Zambetti M, Hrushesky WJ, Retsky MW, Valagussa P, Bonadonna G. Breast cancer recurrence dynamics following adjuvant CMF is consistent with tumor dormancy and mastectomy-driven acceleration of the metastatic process. Ann Oncol. 2005 Sep; 16(9):1449-57. PMID: 15956037.
      Citations:    
    84. Wood PA, Hrushesky WJ, Wood PA, Hrushesky WJ. Sex cycle modulates cancer growth. Breast Cancer Res Treat. 2005 May; 91(1):95-102. PMID: 15868436.
      Citations:    
    85. You S, Wood PA, Xiong Y, Kobayashi M, Du-Quiton J, Hrushesky WJ, You S, Wood PA, Xiong Y, Kobayashi M, Du-Quiton J, Hrushesky WJ. Daily coordination of cancer growth and circadian clock gene expression. Breast Cancer Res Treat. 2005 May; 91(1):47-60. PMID: 15868431.
      Citations:    
    86. Baum M, Demicheli R, Hrushesky W, Retsky M, Baum M, Demicheli R, Hrushesky W, Retsky M. Does surgery unfavourably perturb the "natural history" of early breast cancer by accelerating the appearance of distant metastases? Eur J Cancer. 2005 Mar; 41(4):508-15. PMID: 15737554.
      Citations:    
    87. Dominitz JA, Boyko EJ, Koepsell TD, Heagerty PJ, Maynard C, Sporleder JL, Stenhouse A, Kling MA, Hrushesky W, Zeilman C, Sontag S, Shah N, Ona F, Anand B, Subik M, Imperiale TF, Nakhle S, Ho SB, Bini EJ, Lockhart B, Ahmad J, Sasaki A, van der Linden B, Toro D, Martinez-Souss J, Huilgol V, Eisen S, Young KA, Dominitz JA, Boyko EJ, Koepsell TD, Heagerty PJ, Maynard C, Sporleder JL, Stenhouse A, Kling MA, Hrushesky W, Zeilman C, Sontag S, Shah N, Ona F, Anand B, Subik M, Imperiale TF, Nakhle S, Ho SB, Bini EJ, Lockhart B, Ahmad J, Sasaki A, van der Linden B, Toro D, Martinez-Souss J, Huilgol V, Eisen S, Young KA. Elevated prevalence of hepatitis C infection in users of United States veterans medical centers. Hepatology. 2005 Jan; 41(1):88-96. PMID: 15619249.
      Citations:    
    88. Retsky M, Demicheli R, Hrushesky W, Speer J, Swartzendruber D, Wardwell R, Retsky M, Demicheli R, Hrushesky W, Speer J, Swartzendruber D, Wardwell R. Recent translational research: computational studies of breast cancer. Breast Cancer Res. 2005; 7(1):37-40. PMID: 15642181; PMCID: PMC1064118.
      Citations:    
    89. Demicheli R, Bonadonna G, Hrushesky WJ, Retsky MW, Valagussa P, Demicheli R, Bonadonna G, Hrushesky WJ, Retsky MW, Valagussa P. Menopausal status dependence of the timing of breast cancer recurrence after surgical removal of the primary tumour. Breast Cancer Res. 2004; 6(6):R689-96. PMID: 15535851; PMCID: PMC1064084.
      Citations:    
    90. Hrushesky W, Wood P, Levi F, von Roemeling R, Bjarnason G, Focan C, Meier K, Cornélissen G, Halberg F, Hrushesky W, Wood P, Levi F, von Roemeling R, Bjarnason G, Focan C, Meier K, Corn?lissen G, Halberg F. A recent illustration of some essentials of circadian chronotherapy study design. J Clin Oncol. 2004 Jul 15; 22(14):2971-2; author reply 2972. PMID: 15254067.
      Citations:    
    91. Orr RK, Hoehn JL, Col NF, You S, Li W, Kobayashi M, Xiong Y, Hrushesky W, Wood P. Creation of a stable mammary tumor cell line that maintains fertility-cycle tumor biology of the parent tumor. In Vitro Cell Dev Biol Anim. 2004 Jul-Aug; 40(7):187-95. PMID: 15161341.
      Citations:    
    92. Hrushesky WJ, Blask DE, Hrushesky WJ, Blask DE. Re: Melatonin and breast cancer: a prospective study. J Natl Cancer Inst. 2004 Jun 02; 96(11):888-9. PMID: 15173281.
      Citations:    
    93. Retsky M, Bonadonna G, Demicheli R, Folkman J, Hrushesky W, Valagussa P, Retsky M, Bonadonna G, Demicheli R, Folkman J, Hrushesky W, Valagussa P. Hypothesis: Induced angiogenesis after surgery in premenopausal node-positive breast cancer patients is a major underlying reason why adjuvant chemotherapy works particularly well for those patients. Breast Cancer Res. 2004; 6(4):R372-4. PMID: 15217504; PMCID: PMC468653.
      Citations:    
    94. Demicheli R, Bonadonna G, Hrushesky WJ, Retsky MW, Valagussa P, Demicheli R, Bonadonna G, Hrushesky WJ, Retsky MW, Valagussa P. Menopausal status dependence of early mortality reduction due to diagnosis of smaller breast cancers (T1 v T2-T3): relevance to screening. J Clin Oncol. 2004 Jan 01; 22(1):102-7. PMID: 14701771.
      Citations: 7     Fields:    Translation:HumansPHPublic Health
    95. Orr RK, Hoehn JL, Col NF, Lis CG, Grutsch JF, Wood P, You M, Rich I, Hrushesky WJ. Circadian timing in cancer treatment: the biological foundation for an integrative approach. Integr Cancer Ther. 2003 Jun; 2(2):105-11. PMID: 15035897.
      Citations:    
    96. Retsky M, Demicheli R, Hrushesky W, Retsky M, Demicheli R, Hrushesky W. Breast cancer screening: controversies and future directions. Curr Opin Obstet Gynecol. 2003 Feb; 15(1):1-8. PMID: 12544495.
      Citations: 11     Fields:    Translation:HumansPHPublic Health
    97. Hrushesky WJ, Hrushesky WJ. Androgen suppression and irradiation for locally advanced prostate cancer. Lancet. 2002 Dec 14; 360(9349):1987; author reply 1987-8. PMID: 12493316.
      Citations:    Fields:    Translation:Humans
    98. Bove K, Lincoln DW, Wood PA, Hrushesky WJ, Bove K, Lincoln DW, Wood PA, Hrushesky WJ. Fertility cycle influence on surgical breast cancer cure. Breast Cancer Res Treat. 2002 Sep; 75(1):65-72. PMID: 12500935.
      Citations: 6     Fields:    Translation:Animals
    99. Retsky M, Demicheli R, Hrushesky W, Retsky M, Demicheli R, Hrushesky W. Breast cancer screening for women aged 40-49 years: screening may not be the benign process usually thought. J Natl Cancer Inst. 2001 Oct 17; 93(20):1572. PMID: 11604483.
      Citations: 6     Fields:    Translation:HumansPHPublic Health
    100. Bjarnason GA, Jordan RC, Wood PA, Li Q, Lincoln DW, Sothern RB, Hrushesky WJ, Ben-David Y, Bjarnason GA, Jordan RC, Wood PA, Li Q, Lincoln DW, Sothern RB, Hrushesky WJ, Ben-David Y. Circadian expression of clock genes in human oral mucosa and skin: association with specific cell-cycle phases. Am J Pathol. 2001 May; 158(5):1793-801. PMID: 11337377; PMCID: PMC1891949.
      Citations: 108     Fields:    Translation:CellsCTClinical Trials
    101. Retsky M, Demicheli R, Hrushesky W, Retsky M, Demicheli R, Hrushesky W. Wounding from biopsy and breast-cancer progression. Lancet. 2001 Mar 31; 357(9261):1048. PMID: 11293631.
      Citations: 4     Fields:    Translation:HumansPHPublic Health
    102. Mizumura Y, Matsumura Y, Hamaguchi T, Nishiyama N, Kataoka K, Kawaguchi T, Hrushesky WJ, Moriyasu F, Kakizoe T, Mizumura Y, Matsumura Y, Hamaguchi T, Nishiyama N, Kataoka K, Kawaguchi T, Hrushesky WJ, Moriyasu F, Kakizoe T. Cisplatin-incorporated polymeric micelles eliminate nephrotoxicity, while maintaining antitumor activity. Jpn J Cancer Res. 2001 Mar; 92(3):328-36. PMID: 11267944; PMCID: PMC5926709.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    103. Retsky M, Demicheli R, Hrushesky W, Retsky M, Demicheli R, Hrushesky W. Premenopausal status accelerates relapse in node positive breast cancer: hypothesis links angiogenesis, screening controversy. Breast Cancer Res Treat. 2001 Feb; 65(3):217-24. PMID: 11336243.
      Citations: 18     Fields:    Translation:HumansCellsPHPublic Health
    104. Lincoln DW, Hrushesky WJ, Wood PA, Lincoln DW, Hrushesky WJ, Wood PA. Circadian organization of thymidylate synthase activity in normal tissues: a possible basis for 5-fluorouracil chronotherapeutic advantage. Int J Cancer. 2000 Nov 01; 88(3):479-85. PMID: 11054680.
      Citations: 12     Fields:    Translation:Animals
    105. Hrushesky WJ, Hrushesky WJ. Rhythmic menstrual cycle modulation of breast cancer biology. J Surg Oncol. 2000 Jul; 74(3):238-41. PMID: 10951427.
      Citations: 1     Fields:    Translation:Humans
    106. Thrall MM, Wood P, King V, Rivera W, Hrushesky W, Thrall MM, Wood P, King V, Rivera W, Hrushesky W. Investigation of the comparative toxicity of 5-FU bolus versus 5-FU continuous infusion circadian chemotherapy with concurrent radiation therapy in locally advanced rectal cancer. Int J Radiat Oncol Biol Phys. 2000 Mar 01; 46(4):873-81. PMID: 10705008.
      Citations: 4     Fields:    Translation:Humans
    107. Hrushesky WJ, Lester B, Lannin D, Hrushesky WJ, Lester B, Lannin D. Circadian coordination of cancer growth and metastatic spread. Int J Cancer. 1999 Oct 29; 83(3):365-73. PMID: 10495429.
      Citations: 5     Fields:    Translation:Animals
    108. Hrushesky WJ, Vyzula R, Wood PA, Hrushesky WJ, Vyzula R, Wood PA. Fertility maintenance and 5-fluorouracil timing within the mammalian fertility cycle. Reprod Toxicol. 1999 Sep-Oct; 13(5):413-20. PMID: 10560591.
      Citations: 5     Fields:    Translation:Animals
    109. Hrushesky WJ, Lannin D, Haus E, Hrushesky WJ, Lannin D, Haus E. Evidence for an ontogenetic basis for circadian coordination of cancer cell proliferation. J Natl Cancer Inst. 1998 Oct 07; 90(19):1480-4. PMID: 9776414.
      Citations: 8     Fields:    Translation:Humans
    110. Wood PA, Hrushesky WJ, Klevecz R, Wood PA, Hrushesky WJ, Klevecz R. Distinct circadian time structures characterize myeloid and erythroid progenitor and multipotential cell clonogenicity as well as marrow precursor proliferation dynamics. Exp Hematol. 1998 Jun; 26(6):523-33. PMID: 9620286.
      Citations: 5     Fields:    Translation:AnimalsCells
    111. Hagen AA, Hrushesky WJ, Hagen AA, Hrushesky WJ. Menstrual timing of breast cancer surgery. Am J Surg. 1998 Mar; 175(3):245-61. PMID: 9560131.
      Citations: 9     Fields:    Translation:HumansAnimals
    112. Hrushesky WJ, Wood PA, Hrushesky WJ, Wood PA. Circadian time structure of septic shock: timing is everything. J Infect Dis. 1997 May; 175(5):1283-4. PMID: 9129107.
      Citations: 7     Fields:    Translation:HumansCells
    113. Tzannis ST, Hrushesky WJ, Wood PA, Przybycien TM, Tzannis ST, Hrushesky WJ, Wood PA, Przybycien TM. Irreversible inactivation of interleukin 2 in a pump-based delivery environment. Proc Natl Acad Sci U S A. 1996 May 28; 93(11):5460-5. PMID: 8643597; PMCID: PMC39268.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    114. Hrushesky WJ, Hrushesky WJ. Menstrual cycle timing of breast cancer resection. Recent Results Cancer Res. 1996; 140:27-40. PMID: 8787069.
      Citations: 1     Fields:    Translation:HumansAnimals
    115. Wood PA, Hrushesky WJ, Wood PA, Hrushesky WJ. Circadian rhythms and cancer chemotherapy. Crit Rev Eukaryot Gene Expr. 1996; 6(4):299-343. PMID: 8959371.
      Citations: 5     Fields:    Translation:HumansAnimals
    116. Wood PA, Hrushesky WJ, Wood PA, Hrushesky WJ. Erythropoietin usage in patients with cancer. Cancer J Sci Am. 1995 Nov-Dec; 1(4):243-6. PMID: 9166482.
      Citations:    Fields:    Translation:Humans
    117. Hrushesky WJ, Hrushesky WJ. Square pegs in round holes. Int J Cancer. 1995 Sep 04; 62(5):651-2. PMID: 7665240.
      Citations:    Fields:    Translation:HumansAnimals
    118. Wong MK, Bjarnason GA, Hrushesky WJ, Webster P, Morava-Protzner I, Towers M, Wong MK, Bjarnason GA, Hrushesky WJ, Webster P, Morava-Protzner I, Towers M. Steroid-responsive interstitial lung disease in patients receiving 2'-deoxy-5-fluorouridine-infusion chemotherapy. A report of three cases. Cancer. 1995 May 15; 75(10):2558-64. PMID: 7736401.
      Citations: 1     Fields:    Translation:Humans
    119. Wood PA, Hrushesky WJ, Wood PA, Hrushesky WJ. Cisplatin-associated anemia: an erythropoietin deficiency syndrome. J Clin Invest. 1995 Apr; 95(4):1650-9. PMID: 7706473; PMCID: PMC295669.
      Citations: 25     Fields:    Translation:HumansAnimals
    120. Hrushesky WJ, Hrushesky WJ. Menstrual cycle timing of breast cancer resection: prospective study is overdue. J Natl Cancer Inst. 1995 Jan 18; 87(2):143-4. PMID: 7707388.
      Citations: 1     Fields:    Translation:Humans
    121. Hrushesky WJ, Hrushesky WJ. Cancer chronotherapy: is there a right time in the day to treat? J Infus Chemother. 1995; 5(1):38-43. PMID: 7634176.
      Citations:    Fields:    Translation:HumansAnimals
    122. Hrushesky WJ, Hrushesky WJ. Larry Scheving and cancer chronotherapy. J Infus Chemother. 1995; 5(1):1-2. PMID: 7634169.
      Citations:    Fields:    Translation:Humans
    123. Wood PA, Hrushesky WJ, Wood PA, Hrushesky WJ. Biological perspectives on circadian cancer therapy. J Infus Chemother. 1995; 5(4):182-90. PMID: 8934723.
      Citations:    Fields:    Translation:Humans
    124. Hrushesky WJ, Hrushesky WJ. The Department of Veterans Affairs' unique clinical cancer research effort. Cancer. 1994 Nov 01; 74(9 Suppl):2701-9. PMID: 7954290.
      Citations:    Fields:    Translation:Humans
    125. Hrushesky WJ, Hrushesky WJ. Mammography and the menstrual cycle. Int J Cancer. 1994 Oct 01; 59(1):151. PMID: 7927896.
      Citations:    Fields:    Translation:Humans
    126. Hrushesky WJ, Langevin T, Kim YJ, Wood PA, Hrushesky WJ, Langevin T, Kim YJ, Wood PA. Circadian dynamics of tumor necrosis factor alpha (cachectin) lethality. J Exp Med. 1994 Sep 01; 180(3):1059-65. PMID: 8064225; PMCID: PMC2191660.
      Citations: 27     Fields:    Translation:Animals
    127. Hrushesky WJ, Hrushesky WJ. Circadian pharmacodynamics of anticancer therapies. Clin Chem. 1993 Nov; 39(11 Pt 2):2413-8. PMID: 8222252.
      Citations:    Fields:    Translation:HumansAnimals
    128. Hrushesky WJ, Bjarnason GA, Hrushesky WJ, Bjarnason GA. Circadian cancer therapy. J Clin Oncol. 1993 Jul; 11(7):1403-17. PMID: 8315438.
      Citations: 21     Fields:    Translation:HumansAnimals
    129. Hrushesky WJ, Hrushesky WJ. Breast cancer and the menstrual cycle. J Surg Oncol. 1993 May; 53(1):1-3. PMID: 8479190.
      Citations: 2     Fields:    Translation:Humans
    130. Hrushesky WJ, Hrushesky WJ. Circadian cancer pharmacodynamics. Ann Ist Super Sanita. 1993; 29(4):705-10. PMID: 7985931.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    131. Traynor K, Newton DW, Hrushesky WJ, Reiter RJ, Traynor K, Newton DW, Hrushesky WJ, Reiter RJ. A pharmacist's primer on chronotherapeutics. Am Pharm. 1992 Mar; NS32(3):77-83. PMID: 1561969.
      Citations: 1     Fields:    Translation:Humans
    132. Bluming AZ, Hrushesky WJ, Bluming AZ, Hrushesky WJ. Optimal timing of initial breast cancer surgery. Ann Intern Med. 1992 Feb 01; 116(3):268. PMID: 1728214.
      Citations:    Fields:    Translation:Humans
    133. Gruber SA, Erdmann GR, Burke BA, Moss A, Bowers L, Hrushesky WJ, Cipolle RJ, Canafax DM, Matas AJ, Gruber SA, Erdmann GR, Burke BA, Moss A, Bowers L, Hrushesky WJ, Cipolle RJ, Canafax DM, Matas AJ. Mizoribine pharmacokinetics and pharmacodynamics in a canine renal allograft model of local immunosuppression. Transplantation. 1992 Jan; 53(1):12-9. PMID: 1733057.
      Citations: 1     Fields:    Translation:Animals
    134. Buchi KN, Moore JG, Hrushesky WJ, Sothern RB, Rubin NH, Buchi KN, Moore JG, Hrushesky WJ, Sothern RB, Rubin NH. Circadian rhythm of cellular proliferation in the human rectal mucosa. Gastroenterology. 1991 Aug; 101(2):410-5. PMID: 2065918.
      Citations: 39     Fields:    Translation:Humans
    135. Hrushesky WJ, Fader DJ, Berestka JS, Sommer M, Hayes J, Cope FO, Hrushesky WJ, Fader DJ, Berestka JS, Sommer M, Hayes J, Cope FO. Diminishment of respiratory sinus arrhythmia foreshadows doxorubicin-induced cardiomyopathy. Circulation. 1991 Aug; 84(2):697-707. PMID: 1860214.
      Citations: 8     Fields:    Translation:Humans
    136. Hrushesky WJ, Hrushesky WJ. Reprogramming SynchroMed pumps: unanticipated inaccuracy. J Clin Oncol. 1991 Jun; 9(6):1089-90. PMID: 2033422.
      Citations:    Fields:    Translation:Humans
    137. Bluming A, Hrushesky WJ, Bluming A, Hrushesky WJ. The effect of surgical timing within the fertility cycle on breast cancer outcome. Ann N Y Acad Sci. 1991; 618:277-91. PMID: 2006789.
      Citations:    Fields:    Translation:Humans
    138. Hrushesky WJ, Hrushesky WJ. The multifrequency (circadian, fertility cycle, and season) balance between host and cancer. Ann N Y Acad Sci. 1991; 618:228-56. PMID: 1826075.
      Citations:    Fields:    Translation:HumansAnimals
    139. Hrushesky WJ, Hrushesky WJ. Temporally optimizable delivery systems--sine qua non for molecular medicine. Preface. Ann N Y Acad Sci. 1991; 618:xi-xvii. PMID: 2006778.
      Citations:    Fields:    Translation:HumansAnimals
    140. Hrushesky WJ, Hrushesky WJ. Quantitative respiratory sinus arrhythmia analysis. A simple noninvasive, reimbursable measure of cardiac wellness and dysfunction. Ann N Y Acad Sci. 1991; 618:67-101. PMID: 2006812.
      Citations: 1     Fields:    Translation:Humans
    141. Hrushesky WJ, von Roemeling R, Lanning RM, Rabatin JT, Hrushesky WJ, von Roemeling R, Lanning RM, Rabatin JT. Circadian-shaped infusions of floxuridine for progressive metastatic renal cell carcinoma. J Clin Oncol. 1990 Sep; 8(9):1504-13. PMID: 2144018.
      Citations: 14     Fields:    Translation:HumansCTClinical Trials
    142. Hrushesky WJ, Hrushesky WJ. Health care for US veterans and others. Lancet. 1990 Jul 21; 336(8708):182. PMID: 1973499.
      Citations:    Fields:    Translation:Humans
    143. Hrushesky WJ, Bluming AZ, Gruber SA, Hrushesky WJ, Bluming AZ, Gruber SA. Menstrual influence on surgical cure of breast cancer. Lancet. 1990 Apr 21; 335(8695):984. PMID: 1970065.
      Citations: 1     Fields:    Translation:HumansAnimals
    144. von Roemeling R, Hrushesky WJ, von Roemeling R, Hrushesky WJ. Determination of the therapeutic index of floxuridine by its circadian infusion pattern. J Natl Cancer Inst. 1990 Mar 07; 82(5):386-93. PMID: 2137540.
      Citations: 7     Fields:    Translation:Animals
    145. Hrushesky WJ, Hrushesky WJ. More evidence for circadian rhythm effects in cancer chemotherapy: the fluoropyrimidine story. Cancer Cells. 1990 Mar; 2(3):65-8. PMID: 2143918.
      Citations: 1     Fields:    Translation:Humans
    146. Gruber SA, Cipolle RJ, Tzardis P, Skjei KL, Jossart G, Abed JF, Canafax DM, Burke BA, Matas AJ, Hrushesky WJ, Gruber SA, Cipolle RJ, Tzardis P, Skjei KL, Jossart G, Abed JF, Canafax DM, Burke BA, Matas AJ, Hrushesky WJ. Pharmacodynamics of local heparin infusion in a canine renal allograft model. J Pharmacol Exp Ther. 1990 Feb; 252(2):733-8. PMID: 2313597.
      Citations:    Fields:    Translation:Animals
    147. Gruber SA, Canafax DM, Cipolle RJ, Erdmann GR, Burke BA, Matas AJ, Simmons RL, Hrushesky WJ, Gruber SA, Canafax DM, Cipolle RJ, Erdmann GR, Burke BA, Matas AJ, Simmons RL, Hrushesky WJ. Local immunosuppression of the vascularized graft. Surgery. 1990 Feb; 107(2):209-14. PMID: 2300900.
      Citations: 2     Fields:    Translation:HumansAnimals
    148. Hrushesky WJ, Hrushesky WJ. Cancer chronotherapy: a drug delivery challenge. Prog Clin Biol Res. 1990; 341A:1-10. PMID: 2145583.
      Citations: 2     Fields:    Translation:HumansAnimalsCTClinical Trials
    149. Lanning RM, Hrushesky WJ, Lanning RM, Hrushesky WJ. Outpatient time-specified infusion of fluoropyrimidines by implanted pump is less costly than flat delivery by external pump. Prog Clin Biol Res. 1990; 341B:397-409. PMID: 2145587.
      Citations:    Fields:    Translation:Humans
    150. Lanning RM, von Roemeling R, Hrushesky WJ, Lanning RM, von Roemeling R, Hrushesky WJ. Circadian-based infusional FUDR therapy. Oncol Nurs Forum. 1990 Jan-Feb; 17(1):49-56. PMID: 2137216.
      Citations:    Fields:    Translation:Humans
    151. Swoyer J, Rhame F, Hrushesky W, Sackett-Lundeen L, Sothern R, Gale H, Haus E, Swoyer J, Rhame F, Hrushesky W, Sackett-Lundeen L, Sothern R, Gale H, Haus E. Circadian rhythm alteration in HIV infected subjects. Prog Clin Biol Res. 1990; 341A:437-49. PMID: 2217264.
      Citations: 4     Fields:    Translation:HumansCells
    152. Sothern RB, Rhame F, Suarez C, Fletcher C, Sackett-Lundeen L, Haus E, Hrushesky WJ, Sothern RB, Rhame F, Suarez C, Fletcher C, Sackett-Lundeen L, Haus E, Hrushesky WJ. Oral temperature rhythmometry and substantial within-day variation in zidovudine levels following steady-state dosing in human immunodeficiency virus (HIV) infection. Prog Clin Biol Res. 1990; 341A:67-76. PMID: 2217285.
      Citations: 2     Fields:    Translation:Humans
    153. Teslow TN, Zermeno A, Hrushesky WJ, Ashkenazi IE, Teslow TN, Zermeno A, Hrushesky WJ, Ashkenazi IE. ChronoBioNet: global and local area networking in the chronobiological sciences. Prog Clin Biol Res. 1990; 341B:461-9. PMID: 2217338.
      Citations:    Fields:    
    154. Schraufek SR, Sothern RB, Voegele M, Ainsworth B, Serfass R, Leon A, Khanuja HS, Hrushesky WJ, Schraufek SR, Sothern RB, Voegele M, Ainsworth B, Serfass R, Leon A, Khanuja HS, Hrushesky WJ. Enhancement of respiratory sinus arrhythmia by moderate exercise. Prog Clin Biol Res. 1990; 341A:283-96. PMID: 2217245.
      Citations:    Fields:    Translation:Humans
    155. Gruber SA, Hrushesky WJ, Canafax DM, Cipolle RJ, Burke BA, Matas AJ, Ascher NL, Simmons RL, Gruber SA, Hrushesky WJ, Canafax DM, Cipolle RJ, Burke BA, Matas AJ, Ascher NL, Simmons RL. Local prednisolone infusion of canine renal allografts. Transplantation. 1989 Dec; 48(6):1072-5. PMID: 2595771.
      Citations:    Fields:    Translation:Animals
    156. Gruber SA, Hrushesky WJ, Cipolle RJ, Erdmann GR, Burke BA, Skjei KL, Mueller RP, Fryd DS, Matas AJ, Simmons RL, Gruber SA, Hrushesky WJ, Cipolle RJ, Erdmann GR, Burke BA, Skjei KL, Mueller RP, Fryd DS, Matas AJ, Simmons RL, et al. Local immunosuppression with reduced systemic toxicity in a canine renal allograft model. Transplantation. 1989 Dec; 48(6):936-43. PMID: 2595782.
      Citations: 3     Fields:    Translation:Animals
    157. von Roemeling R, Hrushesky WJ, von Roemeling R, Hrushesky WJ. Circadian patterning of continuous floxuridine infusion reduces toxicity and allows higher dose intensity in patients with widespread cancer. J Clin Oncol. 1989 Nov; 7(11):1710-9. PMID: 2530318.
      Citations: 9     Fields:    Translation:HumansCTClinical Trials
    158. Hrushesky WJ, Bluming AZ, Gruber SA, Sothern RB, Hrushesky WJ, Bluming AZ, Gruber SA, Sothern RB. Menstrual influence on surgical cure of breast cancer. Lancet. 1989 Oct 21; 2(8669):949-52. PMID: 2571865.
      Citations: 34     Fields:    Translation:Humans
    159. Gruber SA, Nichol KL, Sothern RB, Malone ME, Potter JD, Lakatua D, Hrushesky WJ, Gruber SA, Nichol KL, Sothern RB, Malone ME, Potter JD, Lakatua D, Hrushesky WJ. Menstrual history and breast cancer surgery. Breast Cancer Res Treat. 1989 Jul; 13(3):278. PMID: 2489021.
      Citations: 1     Fields:    Translation:Humans
    160. Berestka JS, Johnson TR, Hrushesky WJ, Berestka JS, Johnson TR, Hrushesky WJ. Sinusoidal fetal heart rate pattern during breathing is related to the respiratory sinus arrhythmia: a case report. Am J Obstet Gynecol. 1989 Mar; 160(3):690-2. PMID: 2648840.
      Citations:    Fields:    Translation:Humans
    161. Gruber SA, Burke BA, Canafax DM, Hrushesky WJ, Cipolle RJ, Erdmann GR, Matas A, Simmons RL, Najarian JS, Gruber SA, Burke BA, Canafax DM, Hrushesky WJ, Cipolle RJ, Erdmann GR, Matas A, Simmons RL, Najarian JS. Feasibility of vascular catheter placement for intrarenal infusion in a canine autotransplant model. Transplant Proc. 1989 Feb; 21(1 Pt 1):1125-6. PMID: 2650074.
      Citations: 1     Fields:    Translation:Animals
    162. Sothern RB, Lévi F, Haus E, Halberg F, Hrushesky WJ, Sothern RB, L?vi F, Haus E, Halberg F, Hrushesky WJ. Control of a murine plasmacytoma with doxorubicin-cisplatin: dependence on circadian stage of treatment. J Natl Cancer Inst. 1989 Jan 18; 81(2):135-45. PMID: 2909754.
      Citations: 7     Fields:    Translation:Animals
    163. Mormont MC, von Roemeling R, Sothern RB, Berestka JS, Langevin TR, Wick M, Hrushesky WJ, Mormont MC, von Roemeling R, Sothern RB, Berestka JS, Langevin TR, Wick M, Hrushesky WJ. Circadian rhythm and seasonal dependence in the toxicological response of mice to epirubicin. Invest New Drugs. 1988 Dec; 6(4):273-83. PMID: 3229940.
      Citations: 1     Fields:    Translation:Animals
    164. Hrushesky WJ, Gruber SA, Sothern RB, Hoffman RA, Lakatua D, Carlson A, Cerra F, Simmons RL, Hrushesky WJ, Gruber SA, Sothern RB, Hoffman RA, Lakatua D, Carlson A, Cerra F, Simmons RL. Natural killer cell activity: age, estrous- and circadian-stage dependence and inverse correlation with metastatic potential. J Natl Cancer Inst. 1988 Oct 05; 80(15):1232-7. PMID: 3262168.
      Citations: 14     Fields:    Translation:AnimalsCells
    165. Gruber SA, Hoffman RA, Sothern RB, Lakatua D, Carlson A, Simmons RL, Hrushesky WJ, Gruber SA, Hoffman RA, Sothern RB, Lakatua D, Carlson A, Simmons RL, Hrushesky WJ. Splenocyte natural killer cell activity and metastatic potential are inversely dependent on estrous stage. Surgery. 1988 Aug; 104(2):398-403. PMID: 3261050.
      Citations: 3     Fields:    Translation:AnimalsCells
    166. Ratajczak HV, Sothern RB, Hrushesky WJ, Ratajczak HV, Sothern RB, Hrushesky WJ. Estrous influence on surgical cure of a mouse breast cancer. J Exp Med. 1988 Jul 01; 168(1):73-83. PMID: 3397703; PMCID: PMC2188982.
      Citations: 14     Fields:    Translation:Animals
    167. Canafax DM, Cipolle RJ, Hrushesky WJ, Rabatin JT, Min DI, Graves NM, Sutherland DE, Bowers LD, Canafax DM, Cipolle RJ, Hrushesky WJ, Rabatin JT, Min DI, Graves NM, Sutherland DE, Bowers LD. The chronopharmacokinetics of cyclosporine and its metabolites in recipients of pancreas allografts. Transplant Proc. 1988 Apr; 20(2 Suppl 2):471-7. PMID: 3284092.
      Citations: 8     Fields:    Translation:Humans
    168. von Roemeling R, Rabatin JT, Fraley EE, Hrushesky WJ, von Roemeling R, Rabatin JT, Fraley EE, Hrushesky WJ. Progressive metastatic renal cell carcinoma controlled by continuous 5-fluoro-2-deoxyuridine infusion. J Urol. 1988 Feb; 139(2):259-62. PMID: 2963142.
      Citations: 3     Fields:    Translation:Humans
    169. Hrushesky WJ, Von Roemeling R, Fraley EE, Rabatin JT, Hrushesky WJ, Von Roemeling R, Fraley EE, Rabatin JT. Circadian-based infusional chrono-chemotherapy controls progressive metastatic renal cell carcinoma. Semin Surg Oncol. 1988; 4(2):110-5. PMID: 2969133.
      Citations: 4     Fields:    Translation:Humans
    170. Cipolle RJ, Canafax DM, Rabatin J, Bowers LD, Sutherland DE, Hrushesky WJ, Cipolle RJ, Canafax DM, Rabatin J, Bowers LD, Sutherland DE, Hrushesky WJ. Time-dependent disposition of cyclosporine after pancreas transplantation, and application of chronopharmacokinetics to improve immunosuppression. Pharmacotherapy. 1988; 8(1):47-51. PMID: 3287355.
      Citations: 3     Fields:    Translation:Humans
    171. Kanabrocki EL, Snedeker PW, Zieher SJ, Raymond R, Gordey J, Bird T, Sothern RB, Hrushesky WJ, Marks G, Olwin JH, Kanabrocki EL, Snedeker PW, Zieher SJ, Raymond R, Gordey J, Bird T, Sothern RB, Hrushesky WJ, Marks G, Olwin JH, et al. Circadian characteristics of dialyzable and non-dialyzable human urinary electrolytes, trace elements and total solids. Chronobiol Int. 1988; 5(2):175-84. PMID: 3401983.
      Citations: 2     Fields:    Translation:HumansCells
    172. Hrushesky WJ, Berestka JS, von Roemeling R, Olshefski R, Langevin TR, Potish RA, Delaney JP, Ellefson M, Schwartz S, Hrushesky WJ, Berestka JS, von Roemeling R, Olshefski R, Langevin TR, Potish RA, Delaney JP, Ellefson M, Schwartz S. Methylene blue protects intestinal mucosa from free radical-mediated sublethal radiation damage. Free Radic Biol Med. 1988; 5(4):207-13. PMID: 3151072.
      Citations: 1     Fields:    Translation:Animals
    173. Scheving LE, Tsai TH, Sothern RB, Hrushesky WJ, Scheving LE, Tsai TH, Sothern RB, Hrushesky WJ. Circadian susceptibility-resistance cycles to radiation and their manipulability by methylene blue. Pharmacol Ther. 1988; 39(1-3):397-402. PMID: 3200897.
      Citations: 1     Fields:    Translation:Animals
    174. Hrushesky WJ, Hrushesky WJ. The rationale for non-zero-order drug delivery using automatic, computer-based drug delivery systems (chronotherapy). J Biol Response Mod. 1987 Dec; 6(6):587-98. PMID: 3450783.
      Citations: 1     Fields:    Translation:Humans
    175. Hrushesky WJ, Nygaard SD, Young J, Hrushesky WJ, Nygaard SD, Young J. Timing may be a critical factor in drug therapy. Cancer Treat Rep. 1987 Dec; 71(12):1321. PMID: 3690550.
      Citations:    Fields:    Translation:Animals
    176. Hrushesky WJ, Roemeling RV, Wood PA, Langevin TR, Lange P, Fraley E, Hrushesky WJ, Roemeling RV, Wood PA, Langevin TR, Lange P, Fraley E. High-dose intensity, circadian-timed doxorubicin and cisplatin adjuvant chemotherapy for bladder cancer. Cancer Treat Rep. 1987 Oct; 71(10):915-9. PMID: 3652055.
      Citations: 1     Fields:    Translation:Humans
    177. Hrushesky WJ, Roemeling RV, Wood PA, Langevin TR, Lange P, Farley E, Hrushesky WJ, Roemeling RV, Wood PA, Langevin TR, Lange P, Farley E. High-dose intensity systemic therapy of metastatic bladder cancer. J Clin Oncol. 1987 Mar; 5(3):450-5. PMID: 3819809.
      Citations:    Fields:    Translation:Humans
    178. Roemeling RV, Hrushesky WJ, Roemeling RV, Hrushesky WJ. Circadian pattern of continuous FUDR infusion reduces toxicities. Prog Clin Biol Res. 1987; 227B:357-73. PMID: 2957701.
      Citations: 2     Fields:    Translation:HumansAnimals
    179. Focan C, Collette J, Levi F, Touitou Y, Hrushesky W, Franchimont P, Focan C, Collette J, Levi F, Touitou Y, Hrushesky W, Franchimont P. [Biological rhythms and tumor markers in man. With special reference to the carcinoembryonic antigen (CEA) and alpha fetoprotein (AFP) in digestive system tumors]. Acta Gastroenterol Belg. 1987 Jan-Feb; 50(1):12-21. PMID: 2447730.
      Citations:    Fields:    Translation:Humans
    180. Hrushesky WJ, von Roemeling R, Hrushesky WJ, von Roemeling R. Chemotherapy-induced vomiting: circadian drug timing as a source of predictable within-patient variability. Cancer Treat Rep. 1986 Nov; 70(11):1347-8. PMID: 3768882.
      Citations: 1     Fields:    Translation:Humans
    181. Focan C, Focan-Henrard D, Collette J, Mechkouri M, Levi F, Hrushesky W, Touitou Y, Franchimont P, Focan C, Focan-Henrard D, Collette J, Mechkouri M, Levi F, Hrushesky W, Touitou Y, Franchimont P. Cancer-associated alteration of circadian rhythms in carcinoembryonic antigen (CEA) and alpha-fetoprotein (AFP) in humans. Anticancer Res. 1986 Sep-Oct; 6(5):1137-44. PMID: 2432830.
      Citations: 4     Fields:    Translation:Humans
    182. von Roemeling R, MacDonald M, Langevin T, Buchwald H, Hrushesky WJ, von Roemeling R, MacDonald M, Langevin T, Buchwald H, Hrushesky WJ. Chemotherapy via implanted infusion pump: new perspectives for delivery of long-term continuous treatment. Oncol Nurs Forum. 1986 Mar-Apr; 13(2):17-24. PMID: 2937021.
      Citations:    Fields:    Translation:Humans
    183. Roemeling RV, Hrushesky WJ, Roemeling RV, Hrushesky WJ. Advanced transitional cell bladder cancer: a treatable disease. Semin Surg Oncol. 1986; 2(2):76-89. PMID: 3331211.
      Citations: 1     Fields:    Translation:Humans
    184. Roemeling RV, Olshefski R, Langevin T, Berestka J, Reusch JJ, Reusch JE, Lakatua D, Wick MR, Hrushesky WJ, Roemeling RV, Olshefski R, Langevin T, Berestka J, Reusch JJ, Reusch JE, Lakatua D, Wick MR, Hrushesky WJ. Cisplatin chronotherapy and disulfiram rescue reduce toxicity without interfering with anticancer activity: animal findings and preliminary clinical experiences. Chronobiol Int. 1986; 3(1):55-64. PMID: 3677194.
      Citations: 2     Fields:    Translation:HumansAnimals
    185. Hrushesky WJ, Hrushesky WJ. Utility of non-invasive instantaneous screening test for drug-induced cardiac damage. J Clin Oncol. 1985 Oct; 3(10):1438-9. PMID: 4045533.
      Citations:    Fields:    Translation:Humans
    186. Roemeling RV, Christiansen NP, Hrushesky WJ, Roemeling RV, Christiansen NP, Hrushesky WJ. Lack of antiemetic effect of high-dose metoclopramide. J Clin Oncol. 1985 Sep; 3(9):1273-6. PMID: 4040959.
      Citations: 2     Fields:    Translation:Humans
    187. Hrushesky WJ, Hrushesky WJ. Distinguishing between renal allograft rejection and cyclosporin nephrotoxicity. Lancet. 1985 Aug 31; 2(8453):501. PMID: 2863520.
      Citations:    Fields:    Translation:Humans
    188. Hrushesky WJ, Hrushesky WJ. Cyclosporine timing and kidney damage. N Engl J Med. 1985 Jul 18; 313(3):184. PMID: 4010713.
      Citations:    Fields:    Translation:Animals
    189. Hrushesky WJ, Hrushesky WJ. Circadian timing of cancer chemotherapy. Science. 1985 Apr 05; 228(4695):73-5. PMID: 3883493.
      Citations: 73     Fields:    Translation:HumansAnimalsCTClinical Trials
    190. Trugman J, Hogenkamp HP, Roelofs R, Hrushesky WJ, Trugman J, Hogenkamp HP, Roelofs R, Hrushesky WJ. Cisplatin neurotoxicity: failure to demonstrate vitamin B12 inactivation. Cancer Treat Rep. 1985 Apr; 69(4):453-5. PMID: 4039629.
      Citations: 1     Fields:    Translation:Humans
    191. Hrushesky WJ, Olshefski R, Wood P, Meshnick S, Eaton JW, Hrushesky WJ, Olshefski R, Wood P, Meshnick S, Eaton JW. Modifying intracellular redox balance: an approach to improving therapeutic index. Lancet. 1985 Mar 09; 1(8428):565-7. PMID: 2857911.
      Citations: 7     Fields:    Translation:AnimalsCells
    192. Rosenberg CA, Hrushesky WJ, Langevin T, Kennedy BJ, Rosenberg CA, Hrushesky WJ, Langevin T, Kennedy BJ. Hormonal and chemotherapeutic treatment of prostatic carcinoma; Dunning adenocarcinoma of the prostate in Copenhagen-Fischer rats. Oncology. 1985; 42(1):48-54. PMID: 3969257.
      Citations: 1     Fields:    Translation:Animals
    193. Magnus G, Cavallini M, Halberg F, Cornelissen G, Sutherland DE, Najarian JA, Hrushesky WJ, Magnus G, Cavallini M, Halberg F, Cornelissen G, Sutherland DE, Najarian JA, Hrushesky WJ. Circadian toxicology of cyclosporin. Toxicol Appl Pharmacol. 1985 Jan; 77(1):181-5. PMID: 3871260.
      Citations: 1     Fields:    Translation:Animals
    194. Hrushesky WJ, Vukelich M, Steiner B, Dell I, Mukai K, Hrushesky WJ, Vukelich M, Steiner B, Dell I, Mukai K. 24-hour mean pulse. Simple predictor of doxorubicin-induced cardiac damage. Am J Med. 1984 Sep; 77(3):399-406. PMID: 6475981.
      Citations:    Fields:    Translation:HumansAnimals
    195. Roelofs RI, Hrushesky W, Rogin J, Rosenberg L, Roelofs RI, Hrushesky W, Rogin J, Rosenberg L. Peripheral sensory neuropathy and cisplatin chemotherapy. Neurology. 1984 Jul; 34(7):934-8. PMID: 6330613.
      Citations: 55     Fields:    Translation:Humans
    196. Hrushesky WJ, Fader D, Schmitt O, Gilbertsen V, Hrushesky WJ, Fader D, Schmitt O, Gilbertsen V. The respiratory sinus arrhythmia: a measure of cardiac age. Science. 1984 Jun 01; 224(4652):1001-4. PMID: 6372092.
      Citations: 23     Fields:    Translation:Humans
    197. Hrushesky WJ, Shimp W, Kennedy BJ, Hrushesky WJ, Shimp W, Kennedy BJ. Lack of age-dependent cisplatin nephrotoxicity. Am J Med. 1984 Apr; 76(4):579-84. PMID: 6538750.
      Citations: 24     Fields:    Translation:Humans
    198. Hrushesky WJ, Vukelich M, Hrushesky WJ, Vukelich M. Circadian mesor of recumbent pulse--cost-effective predictor of doxorubicin-induced congestive heart failure. Chronobiol Int. 1984; 1(1):59-66. PMID: 6600010.
      Citations:    Fields:    Translation:HumansAnimals
    199. Hrushesky WJ, Hrushesky WJ. The clinical application of chronobiology to oncology. Am J Anat. 1983 Dec; 168(4):519-42. PMID: 6198896.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    200. Hrushesky WJ, Merdink J, Abdel-Monem MM, Hrushesky WJ, Merdink J, Abdel-Monem MM. Circadian rhythmicity of polyamine urinary excretion. Cancer Res. 1983 Aug; 43(8):3944-7. PMID: 6861156.
      Citations: 1     Fields:    Translation:Humans
    201. Levi F, Hrushesky WJ, Borch RF, Pleasants ME, Kennedy BJ, Halberg F, Levi F, Hrushesky WJ, Borch RF, Pleasants ME, Kennedy BJ, Halberg F. Cisplatin urinary pharmacokinetics and nephrotoxicity: a common circadian mechanism. Cancer Treat Rep. 1982 Nov; 66(11):1933-8. PMID: 6890406.
      Citations: 10     Fields:    Translation:Animals
    202. Hrushesky WJ, Borch R, Levi F, Hrushesky WJ, Borch R, Levi F. Circadian time dependence of cisplatin urinary kinetics. Clin Pharmacol Ther. 1982 Sep; 32(3):330-9. PMID: 7201905.
      Citations: 10     Fields:    Translation:HumansAnimals
    203. Levi FA, Hrushesky WJ, Halberg F, Langevin TR, Haus E, Kennedy BJ, Levi FA, Hrushesky WJ, Halberg F, Langevin TR, Haus E, Kennedy BJ. Lethal nephrotoxicity and hematologic toxicity of cis-diamminedichloroplatinum ameliorated by optimal circadian timing and hydration. Eur J Cancer Clin Oncol. 1982 May; 18(5):471-7. PMID: 6889525.
      Citations: 11     Fields:    Translation:Animals
    204. Levi FA, Hrushesky WJ, Blomquist CH, Lakatua DJ, Haus E, Halberg F, Kennedy BJ, Levi FA, Hrushesky WJ, Blomquist CH, Lakatua DJ, Haus E, Halberg F, Kennedy BJ. Reduction of cis-diamminedichloroplatinum nephrotoxicity in rats by optimal circadian drug timing. Cancer Res. 1982 Mar; 42(3):950-5. PMID: 7199382.
      Citations: 12     Fields:    Translation:Animals
    205. Hrushesky WJ, Levi FA, Halberg F, Kennedy BJ, Hrushesky WJ, Levi FA, Halberg F, Kennedy BJ. Circadian stage dependence of cis-diamminedichloroplatinum lethal toxicity in rats. Cancer Res. 1982 Mar; 42(3):945-9. PMID: 7199381.
      Citations: 12     Fields:    Translation:Animals
    206. Hrushesky WJ, Hrushesky WJ. Unusual pigmentary changes associated with 5-fluorouracil therapy. Cutis. 1980 Aug; 26(2):181-82. PMID: 7408538.
      Citations: 1     Fields:    Translation:Humans
    207. Haus E, Halberg F, Sothern RB, Lakatua D, Scheving LE, Sanchez de la Peña S, Sanchez E, Melby J, Wilson T, Brown H, Berg H, Levi F, Culley D, Halberg E, Hrushesky W, Pauly J, Haus E, Halberg F, Sothern RB, Lakatua D, Scheving LE, Sanchez de la Pe?a S, Sanchez E, Melby J, Wilson T, Brown H, Berg H, Levi F, Culley D, Halberg E, Hrushesky W, Pauly J. Time-varying effects in mice and rats of several synthetic ACTH preparations. Chronobiologia. 1980 Apr-Jun; 7(2):211-26. PMID: 6253238.
      Citations:    Fields:    Translation:Animals
    208. Levi F, Halberg F, Haus E, Sanchez de la Peña S, Sothern RB, Halberg E, Hrushesky W, Brown H, Scheving LE, Kennedy BJ, Levi F, Halberg F, Haus E, Sanchez de la Pe?a S, Sothern RB, Halberg E, Hrushesky W, Brown H, Scheving LE, Kennedy BJ. Synthetic adrenocorticotropin for optimizing murine circadian chronotolerance for adriamycin. Chronobiologia. 1980 Apr-Jun; 7(2):227-44. PMID: 6253239.
      Citations:    Fields:    Translation:Animals
    209. Gordon LI, Hrushesky W, Oken MM, Kay NE, Rydell RE, Gordon LI, Hrushesky W, Oken MM, Kay NE, Rydell RE. Chronic lymphocytic leukemia in association with a second lymphoproliferative disorder: response to chemotherapy in two cases. Med Pediatr Oncol. 1979; 7(2):111-6. PMID: 388174.
      Citations:    Fields:    Translation:Humans
    210. Hrushesky WJ, Hrushesky WJ. Subcutaneous heparin-induced thrombocytopenia. Arch Intern Med. 1978 Oct; 138(10):1489-91. PMID: 708169.
      Citations: 2     Fields:    Translation:HumansCells
    211. Hrushesky W, Hrushesky W. Platelet hyperaggregability and thrombocythemia. Ann Intern Med. 1978 Jun; 88(6):845-6. PMID: 666151.
      Citations:    Fields:    Translation:HumansCells
    212. Hrushesky W, Hrushesky W. Thrombocytopenia induced by low-dose subcutaneous heparin. Lancet. 1977 Dec 17; 2(8051):1286. PMID: 73980.
      Citations: 1     Fields:    Translation:Humans
    213. Hrushesky WJ, Murphy GP, Hrushesky WJ, Murphy GP. Current status of the therapy of advanced renal carcinoma. J Surg Oncol. 1977; 9(3):277-88. PMID: 327158.
      Citations: 14     Fields:    Translation:HumansAnimals
    214. Hrushesky WJ, Hrushesky WJ. Letter: Serpentine supravenous fluorouracil hyperpigmentation. JAMA. 1976 Jul 12; 236(2):138. PMID: 947001.
      Citations: 3     Fields:    Translation:Humans
    215. Hrushesky W, Hrushesky W. L-asparaginase activity in acute nonlymphocytic leukemia. Cancer Treat Rep. 1976 Jul; 60(7):966-7. PMID: 1009534.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    216. Hrushesky WJ, Hrushesky WJ. Serpentine supravenous 5-fluorouracil (NSC-19893) hyperpigmentation. Cancer Treat Rep. 1976 May; 60(5):639. PMID: 991154.
      Citations: 1     Fields:    Translation:Humans
    217. Hrushesky WJ, Slavik M, Penta J, Muggia F, Hrushesky WJ, Slavik M, Penta J, Muggia F. The "other" asparaginase. Med Pediatr Oncol. 1976; 2(4):441-2. PMID: 794672.
      Citations: 1     Fields:    Translation:HumansCells
    218. Hrushesky WJ, Murphy GP, Hrushesky WJ, Murphy GP. Evaluation of chemotherapeutic agents in a new murine renal carcinoma model. J Natl Cancer Inst. 1974 Apr; 52(4):1117-22. PMID: 4826582.
      Citations: 2     Fields:    Translation:Animals
    219. Williams PD, Hrushesky W, Gaeta JF, Murphy GP, Williams PD, Hrushesky W, Gaeta JF, Murphy GP. Influence of hormone therapy on rats treated with the carcinogen ethylmethanesulphonate. Res Commun Chem Pathol Pharmacol. 1974 Jan; 7(1):25-30. PMID: 4359608.
      Citations: 1     Fields:    Translation:Animals
    220. Hrushesky WJ, Murphy GP, Hrushesky WJ, Murphy GP. Investigation of a new renal tumor model. J Surg Res. 1973 Nov; 15(5):327-36. PMID: 4759685.
      Citations: 5     Fields:    Translation:AnimalsCells
    221. Murphy GP, Hrushesky WJ, Murphy GP, Hrushesky WJ. A murine renal cell carcinoma. J Natl Cancer Inst. 1973 Apr; 50(4):1013-25. PMID: 4703766.
      Citations: 31     Fields:    Translation:AnimalsCells
    222. Hrushesky W, Sampson D, Murphy GP, Hrushesky W, Sampson D, Murphy GP. Carcinogenicity of ethylmethanesulfonate. J Natl Cancer Inst. 1972 Oct; 49(4):1077-83. PMID: 5084121.
      Citations: 2     Fields:    Translation:Animals
    223. Hrushesky W, Sampson D, Murphy GP, Hrushesky W, Sampson D, Murphy GP. Lymphocyturia in human renal allograft rejection. Arch Surg. 1972 Sep; 105(3):424-6. PMID: 4115725.
      Citations:    Fields:    Translation:HumansCells
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