Xingbao Li

Title
InstitutionMedical University of South Carolina
DepartmentPsychiatry and Behavioral Sciences
AddressP.O. Box MSC 861
PH505C
67 President St.
Phone843-792-5729
Fax843-792-5702
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    Collapse Biography 
    Collapse education and training
    Jining Medical College, Shandong, ChinaM.D.07/1982Internal Medicine
    Chongqing Medical University, Chongqing, ChinaM.S.07/1990Psychiatry
    Medical University of South Carolina, Charleston, SC, USAM.S.C.R.05/2019Clinical Trials

    Collapse Overview 
    Collapse overview
    Dr. Xingbao Li received his M.D. in Clinical Medicine from Jining Medical College and his M.S. in Psychiatry from Chongqing University of Medical Sciences in China. In May 2019, he completed his Master of Science in Clinical Research at Medical University of South Carolina. His research interests include transcranial magnetic stimulation (TMS) in neuropsychiatry, combining TMS and functional MRI techniques in neuropharmacology, functional MRI in alcoholism and other substance abuse.
    Collapse keywords
    Healthy Volunteer Studies, Stroke, Brain, Smoking, Rehabilitation Studies

    Collapse ORNG Applications 
    Collapse studies/trials

    Collapse Research 
    Collapse research activities and funding
    R21DA036752     (LI, XINGBAO)Apr 15, 2014 - Jul 31, 2016
    NIH
    Developing rTMS as a Potential Treatment for Nicotine Addiction
    Role: Principal Investigator

    UG3DA048507     (LI, XINGBAO)May 15, 2021 - Apr 30, 2023
    NIH
    RTMS manipulates imbalanced drive-reward and executive control circuitry for smoking cessation
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Li X, Hartwell KJ, Henderson S, Badran BW, Brady KT, George MS. Two weeks of image-guided left dorsolateral prefrontal cortex repetitive transcranial magnetic stimulation improves smoking cessation: A double-blind, sham-controlled, randomized clinical trial. Brain Stimul. 2020 Sep - Oct; 13(5):1271-1279. PMID: 32534252.
      Citations:    
    2. Liu H, Luo Q, Du W, Li X, Zhang Z, Yu R, Chen X, Meng H, Du L. Cigarette smoking and schizophrenia independently and reversibly altered intrinsic brain activity. Brain Imaging Behav. 2018 Oct; 12(5):1457-1465. PMID: 29297153.
      Citations:    
    3. Li X, Sahlem GL, Badran BW, McTeague LM, Hanlon CA, Hartwell KJ, Henderson S, George MS. Transcranial magnetic stimulation of the dorsal lateral prefrontal cortex inhibits medial orbitofrontal activity in smokers. Am J Addict. 2017 Dec; 26(8):788-794. PMID: 28898485.
      Citations:    
    4. Li X, Du L, Sahlem GL, Badran BW, Henderson S, George MS. Repetitive transcranial magnetic stimulation (rTMS) of the dorsolateral prefrontal cortex reduces resting-state insula activity and modulates functional connectivity of the orbitofrontal cortex in cigarette smokers. Drug Alcohol Depend. 2017 05 01; 174:98-105. PMID: 28319755.
      Citations:    
    5. Malcolm R, Myrick H, Li X, Henderson S, Brady KT, George MS, See RE. Regional Brain Activity in Abstinent Methamphetamine Dependent Males Following Cue Exposure. J Drug Abuse. 2016; 2(1). PMID: 27314105.
      Citations:    
    6. Hartwell KJ, Hanlon CA, Li X, Borckardt JJ, Canterberry M, Prisciandaro JJ, Moran-Santa Maria MM, LeMatty T, George MS, Brady KT. Individualized real-time fMRI neurofeedback to attenuate craving in nicotine-dependent smokers. J Psychiatry Neurosci. 2016 Jan; 41(1):48-55. PMID: 26505139.
      Citations:    
    7. Liu Y, Du L, Li Y, Liu H, Zhao W, Liu D, Zeng J, Li X, Fu Y, Qiu H, Li X, Qiu T, Hu H, Meng H, Luo Q. Antidepressant Effects of Electroconvulsive Therapy Correlate With Subgenual Anterior Cingulate Activity and Connectivity in Depression. Medicine (Baltimore). 2015 Nov; 94(45):e2033. PMID: 26559309.
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    8. Hanlon CA, DeVries W, Dowdle LT, West JA, Siekman B, Li X, George MS. A comprehensive study of sensorimotor cortex excitability in chronic cocaine users: Integrating TMS and functional MRI data. Drug Alcohol Depend. 2015 Dec 01; 157:28-35. PMID: 26541870.
      Citations:    
    9. Li X, Fryml L, Rodriguez JJ, Taylor J, Borckardt JJ, Short B, Sahlem G, Roberts D, George MS. Safe management of a bipolar depressed patient with prefrontal repetitive transcranial magnetic stimulation (rTMS) Over 7 years and >2 million stimuli. Brain Stimul. 2014 Nov-Dec; 7(6):919-21. PMID: 25440291.
      Citations:    
    10. Schacht JP, Anton RF, Randall PK, Li X, Henderson S, Myrick H. Varenicline effects on drinking, craving and neural reward processing among non-treatment-seeking alcohol-dependent individuals. Psychopharmacology (Berl). 2014 Sep; 231(18):3799-807. PMID: 24647921.
      Citations:    
    11. Xu M, Li X, Sun Z, Tu T. Suzuki-Miyaura cross-coupling of bulky anthracenyl carboxylates by using pincer nickel N-heterocyclic carbene complexes: an efficient protocol to access fluorescent anthracene derivatives. Chem Commun (Camb). 2013 Dec 21; 49(98):11539-41. PMID: 24177710.
      Citations:    
    12. Li X, Malcolm RJ, Huebner K, Hanlon CA, Taylor JJ, Brady KT, George MS, See RE. Low frequency repetitive transcranial magnetic stimulation of the left dorsolateral prefrontal cortex transiently increases cue-induced craving for methamphetamine: a preliminary study. Drug Alcohol Depend. 2013 Dec 01; 133(2):641-6. PMID: 24028801.
      Citations:    
    13. Canterberry M, Hanlon CA, Hartwell KJ, Li X, Owens M, LeMatty T, Prisciandaro JJ, Borckardt J, Saladin ME, Brady KT, George MS. Sustained reduction of nicotine craving with real-time neurofeedback: exploring the role of severity of dependence. Nicotine Tob Res. 2013 Dec; 15(12):2120-4. PMID: 23935182.
      Citations:    
    14. Hanlon CA, Canterberry M, Taylor JJ, DeVries W, Li X, Brown TR, George MS. Probing the frontostriatal loops involved in executive and limbic processing via interleaved TMS and functional MRI at two prefrontal locations: a pilot study. PLoS One. 2013; 8(7):e67917. PMID: 23874466.
      Citations:    
    15. Hanlon CA, Hartwell KJ, Canterberry M, Li X, Owens M, Lematty T, Prisciandaro JJ, Borckardt J, Brady KT, George MS. Reduction of cue-induced craving through realtime neurofeedback in nicotine users: the role of region of interest selection and multiple visits. Psychiatry Res. 2013 Jul 30; 213(1):79-81. PMID: 23683344.
      Citations:    
    16. Li X, Hartwell KJ, Owens M, Lematty T, Borckardt JJ, Hanlon CA, Brady KT, George MS. Repetitive transcranial magnetic stimulation of the dorsolateral prefrontal cortex reduces nicotine cue craving. Biol Psychiatry. 2013 Apr 15; 73(8):714-20. PMID: 23485014.
      Citations:    
    17. Schacht JP, Anton RF, Randall PK, Li X, Henderson S, Myrick H. Effects of a GABA-ergic medication combination and initial alcohol withdrawal severity on cue-elicited brain activation among treatment-seeking alcoholics. Psychopharmacology (Berl). 2013 Jun; 227(4):627-37. PMID: 23389755.
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    18. Taylor JJ, Borckardt JJ, Canterberry M, Li X, Hanlon CA, Brown TR, George MS. Naloxone-reversible modulation of pain circuitry by left prefrontal rTMS. Neuropsychopharmacology. 2013 Jun; 38(7):1189-97. PMID: 23314221.
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    19. Ricci R, Salatino A, Li X, Funk AP, Logan SL, Mu Q, Johnson KA, Bohning DE, George MS. Imaging the neural mechanisms of TMS neglect-like bias in healthy volunteers with the interleaved TMS/fMRI technique: preliminary evidence. Front Hum Neurosci. 2012; 6:326. PMID: 23251130.
      Citations:    
    20. Schacht JP, Anton RF, Voronin KE, Randall PK, Li X, Henderson S, Myrick H. Interacting effects of naltrexone and OPRM1 and DAT1 variation on the neural response to alcohol cues. Neuropsychopharmacology. 2013 Feb; 38(3):414-22. PMID: 23032071.
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    21. Hartwell KJ, Prisciandaro JJ, Borckardt J, Li X, George MS, Brady KT. Real-time fMRI in the treatment of nicotine dependence: a conceptual review and pilot studies. Psychol Addict Behav. 2013 Jun; 27(2):501-9. PMID: 22564200.
      Citations:    
    22. Hanlon CA, Jones EM, Li X, Hartwell KJ, Brady KT, George MS. Individual variability in the locus of prefrontal craving for nicotine: implications for brain stimulation studies and treatments. Drug Alcohol Depend. 2012 Oct 01; 125(3):239-43. PMID: 22459915.
      Citations:    
    23. Li X, Hartwell KJ, Borckardt J, Prisciandaro JJ, Saladin ME, Morgan PS, Johnson KA, Lematty T, Brady KT, George MS. Volitional reduction of anterior cingulate cortex activity produces decreased cue craving in smoking cessation: a preliminary real-time fMRI study. Addict Biol. 2013 Jul; 18(4):739-48. PMID: 22458676.
      Citations:    
    24. Johnson KA, Baig M, Ramsey D, Lisanby SH, Avery D, McDonald WM, Li X, Bernhardt ER, Haynor DR, Holtzheimer PE, Sackeim HA, George MS, Nahas Z. Prefrontal rTMS for treating depression: location and intensity results from the OPT-TMS multi-site clinical trial. Brain Stimul. 2013 Mar; 6(2):108-17. PMID: 22465743.
      Citations:    
    25. Li X, Large CH, Ricci R, Taylor JJ, Nahas Z, Bohning DE, Morgan P, George MS. Using interleaved transcranial magnetic stimulation/functional magnetic resonance imaging (fMRI) and dynamic causal modeling to understand the discrete circuit specific changes of medications: lamotrigine and valproic acid changes in motor or prefrontal effective connectivity. Psychiatry Res. 2011 Nov 30; 194(2):141-8. PMID: 21924874.
      Citations:    
    26. Hartwell KJ, Johnson KA, Li X, Myrick H, LeMatty T, George MS, Brady KT. Neural correlates of craving and resisting craving for tobacco in nicotine dependent smokers. Addict Biol. 2011 Oct; 16(4):654-66. PMID: 21790899.
      Citations:    
    27. Hadley D, Anderson BS, Borckardt JJ, Arana A, Li X, Nahas Z, George MS. Safety, tolerability, and effectiveness of high doses of adjunctive daily left prefrontal repetitive transcranial magnetic stimulation for treatment-resistant depression in a clinical setting. J ECT. 2011 Mar; 27(1):18-25. PMID: 21343710.
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    28. Kozel FA, Johnson KA, Nahas Z, Nakonezny PA, Morgan PS, Anderson BS, Kose S, Li X, Lim KO, Trivedi MH, George MS. Fractional anisotropy changes after several weeks of daily left high-frequency repetitive transcranial magnetic stimulation of the prefrontal cortex to treat major depression. J ECT. 2011 Mar; 27(1):5-10. PMID: 20559144.
      Citations:    
    29. Schacht JP, Anton RF, Randall PK, Li X, Henderson S, Myrick H. Stability of fMRI striatal response to alcohol cues: a hierarchical linear modeling approach. Neuroimage. 2011 May 01; 56(1):61-8. PMID: 21316465.
      Citations:    
    30. Myrick H, Li X, Randall PK, Henderson S, Voronin K, Anton RF. The effect of aripiprazole on cue-induced brain activation and drinking parameters in alcoholics. J Clin Psychopharmacol. 2010 Aug; 30(4):365-72. PMID: 20571434.
      Citations:    
    31. Li X, Ricci R, Large CH, Anderson B, Nahas Z, Bohning DE, George MS. Interleaved transcranial magnetic stimulation and fMRI suggests that lamotrigine and valproic acid have different effects on corticolimbic activity. Psychopharmacology (Berl). 2010 Apr; 209(3):233-44. PMID: 20195575.
      Citations:    
    32. Large CH, Di Daniel E, Li X, George MS. Neural network dysfunction in bipolar depression: clues from the efficacy of lamotrigine. Biochem Soc Trans. 2009 Oct; 37(Pt 5):1080-4. PMID: 19754456.
      Citations:    
    33. Borckardt JJ, Linder KJ, Ricci R, Li X, Anderson B, Arana A, Nahas Z, Amassian V, Long J, George MS, Sackeim HA. Focal electrically administered therapy: device parameter effects on stimulus perception in humans. J ECT. 2009 Jun; 25(2):91-8. PMID: 19092677.
      Citations:    
    34. Li X, Ricci R, Large CH, Anderson B, Nahas Z, George MS. Lamotrigine and valproic acid have different effects on motorcortical neuronal excitability. J Neural Transm (Vienna). 2009 Apr; 116(4):423-9. PMID: 19238517.
      Citations:    
    35. Myrick H, Anton RF, Li X, Henderson S, Randall PK, Voronin K. Effect of naltrexone and ondansetron on alcohol cue-induced activation of the ventral striatum in alcohol-dependent people. Arch Gen Psychiatry. 2008 Apr; 65(4):466-75. PMID: 18391135.
      Citations:    
    36. Arana AB, Borckardt JJ, Ricci R, Anderson B, Li X, Linder KJ, Long J, Sackeim HA, George MS. Focal electrical stimulation as a sham control for repetitive transcranial magnetic stimulation: Does it truly mimic the cutaneous sensation and pain of active prefrontal repetitive transcranial magnetic stimulation? Brain Stimul. 2008 Jan; 1(1):44-51. PMID: 19424459.
      Citations:    
    37. Bedwell JS, Horner MD, Yamanaka K, Li X, Myrick H, Nahas Z, George MS. Functional neuroanatomy of subcomponent cognitive processes involved in verbal working memory. Int J Neurosci. 2005 Jul; 115(7):1017-32. PMID: 16051547.
      Citations:    
    38. Li X, Tang J, Wu Z, Zhao G, Liu C, George MS. SPECT study of Chinese schizophrenic patients suggests that cerebral hypoperfusion and laterality exist in different ethnic groups. World J Biol Psychiatry. 2005; 6(2):98-106. PMID: 16156482.
      Citations:    
    39. Mishory A, Molnar C, Koola J, Li X, Kozel FA, Myrick H, Stroud Z, Nahas Z, George MS. The maximum-likelihood strategy for determining transcranial magnetic stimulation motor threshold, using parameter estimation by sequential testing is faster than conventional methods with similar precision. J ECT. 2004 Sep; 20(3):160-5. PMID: 15343000.
      Citations:    
    40. Li X, Tenebäck CC, Nahas Z, Kozel FA, Large C, Cohn J, Bohning DE, George MS. Interleaved transcranial magnetic stimulation/functional MRI confirms that lamotrigine inhibits cortical excitability in healthy young men. Neuropsychopharmacology. 2004 Jul; 29(7):1395-407. PMID: 15100699.
      Citations:    
    41. Chae JH, Nahas Z, Wassermann E, Li X, Sethuraman G, Gilbert D, Sallee FR, George MS. A pilot safety study of repetitive transcranial magnetic stimulation (rTMS) in Tourette's syndrome. Cogn Behav Neurol. 2004 Jun; 17(2):109-17. PMID: 15453520.
      Citations:    
    42. Li X, Nahas Z, Kozel FA, Anderson B, Bohning DE, George MS. Acute left prefrontal transcranial magnetic stimulation in depressed patients is associated with immediately increased activity in prefrontal cortical as well as subcortical regions. Biol Psychiatry. 2004 May 01; 55(9):882-90. PMID: 15110731.
      Citations:    
    43. Myrick H, Anton RF, Li X, Henderson S, Drobes D, Voronin K, George MS. Differential brain activity in alcoholics and social drinkers to alcohol cues: relationship to craving. Neuropsychopharmacology. 2004 Feb; 29(2):393-402. PMID: 14679386.
      Citations:    
    44. Nahas Z, Li X, Kozel FA, Mirzki D, Memon M, Miller K, Yamanaka K, Anderson B, Chae JH, Bohning DE, Mintzer J, George MS. Safety and benefits of distance-adjusted prefrontal transcranial magnetic stimulation in depressed patients 55-75 years of age: a pilot study. Depress Anxiety. 2004; 19(4):249-56. PMID: 15274174.
      Citations:    
    45. Li X, Nahas Z, Anderson B, Kozel FA, George MS. Can left prefrontal rTMS be used as a maintenance treatment for bipolar depression? Depress Anxiety. 2004; 20(2):98-100. PMID: 15390210.
      Citations:    
    46. George MS, Nahas Z, Kozol FA, Li X, Yamanaka K, Mishory A, Bohning DE. Mechanisms and the current state of transcranial magnetic stimulation. CNS Spectr. 2003 Jul; 8(7):496-514. PMID: 12894031.
      Citations:    
    47. Nahas Z, George MS, Horner MD, Markowitz JS, Li X, Lorberbaum JP, Owens SD, McGurk S, DeVane L, Risch SC. Augmenting atypical antipsychotics with a cognitive enhancer (donepezil) improves regional brain activity in schizophrenia patients: a pilot double-blind placebo controlled BOLD fMRI study. Neurocase. 2003 Jun; 9(3):274-82. PMID: 12925933.
      Citations:    
    48. Li X, Nahas Z, Lomarev M, Denslow S, Shastri A, Bohning DE, George MS. Prefrontal cortex transcranial magnetic stimulation does not change local diffusion: a magnetic resonance imaging study in patients with depression. Cogn Behav Neurol. 2003 Jun; 16(2):128-35. PMID: 12799599.
      Citations:    
    49. Nahas Z, Kozel FA, Li X, Anderson B, George MS. Left prefrontal transcranial magnetic stimulation (TMS) treatment of depression in bipolar affective disorder: a pilot study of acute safety and efficacy. Bipolar Disord. 2003 Feb; 5(1):40-7. PMID: 12656937.
      Citations:    
    50. George MS, Nahas Z, Kozel FA, Li X, Denslow S, Yamanaka K, Mishory A, Foust MJ, Bohning DE. Mechanisms and state of the art of transcranial magnetic stimulation. J ECT. 2002 Dec; 18(4):170-81. PMID: 12468991.
      Citations:    
    51. Nahas Z, Li X, Chae JH, Oliver NC, Anderson B, Kapp B, George MS. What Does ECS Stand for? Repetitive Transcranial Magnetic Stimulation in Depression. Volume 2, Number 3, Part 2 (June 1, 2001), pages S21-S29. Epilepsy Behav. 2001 Aug; 2(4):375. PMID: 12609217.
      Citations:    
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