"Stem Cell Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A hematopoietic growth factor and the ligand of the cell surface c-kit protein (PROTO-ONCOGENE PROTEINS C-KIT). It is expressed during embryogenesis and is a growth factor for a number of cell types including the MAST CELLS and the MELANOCYTES in addition to the HEMATOPOIETIC STEM CELLS.
| Descriptor ID |
D019089
|
| MeSH Number(s) |
D12.644.276.374.410.800 D12.776.467.374.410.800 D23.529.374.410.800
|
| Concept/Terms |
Stem Cell Factor- Stem Cell Factor
- Steel Factor
- Mast Cell Growth Factor
- c-kit Ligand
- c kit Ligand
- kit Ligand
|
Below are MeSH descriptors whose meaning is more general than "Stem Cell Factor".
Below are MeSH descriptors whose meaning is more specific than "Stem Cell Factor".
This graph shows the total number of publications written about "Stem Cell Factor" by people in this website by year, and whether "Stem Cell Factor" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 7 | 7 |
| 1995 | 0 | 5 | 5 |
| 1996 | 3 | 2 | 5 |
| 1997 | 2 | 1 | 3 |
| 1998 | 1 | 2 | 3 |
| 1999 | 1 | 2 | 3 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2003 | 2 | 0 | 2 |
| 2012 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Stem Cell Factor" by people in Profiles.
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Immune responses in a mouse model of vitiligo with spontaneous epidermal de- and repigmentation. Pigment Cell Melanoma Res. 2014 Nov; 27(6):1075-85.
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Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia. Nat Med. 2012 Mar 11; 18(4):605-11.
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Extracellular KIT receptor mutants, commonly found in core binding factor AML, are constitutively active and respond to imatinib mesylate. Blood. 2005 Dec 01; 106(12):3958-61.
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Recombinant human (rh) stem cell factor and rhIL-4 stimulate differentiation and proliferation of CD3+ cells from umbilical cord blood and CD3+ cells enhance FcepsilonR1 expression on fetal liver-derived mast cells in the presence of rhIL-4. Cell Immunol. 2003 Nov; 226(1):30-6.
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Hematopoietic recovery after unrelated umbilical cord-blood allogeneic transplantation in adults treated with in vivo stem cell factor (R-MetHuSCF) and filgrastim administration. Leuk Res. 2003 Mar; 27(3):215-20.
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Human stem-progenitor cells from neonatal cord blood have greater hematopoietic expansion capacity than those from mobilized adult blood. Exp Hematol. 2002 Jul; 30(7):816-23.
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IL-6 attenuates apoptosis, while neither IL-6 nor IL-10 affect the numbers or protease phenotype of fetal liver-derived human mast cells. Clin Exp Allergy. 2001 Jul; 31(7):1077-85.
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CD34 expression by murine hematopoietic stem cells. Developmental changes and kinetic alterations. Ann N Y Acad Sci. 2001 Jun; 938:139-45.
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Recombinant human (rh)IL-4-mediated apoptosis and recombinant human IL-6-mediated protection of recombinant human stem cell factor-dependent human mast cells derived from cord blood mononuclear cell progenitors. J Immunol. 1999 Nov 01; 163(9):5105-15.
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Reversible expression of CD34 by murine hematopoietic stem cells. Blood. 1999 Oct 15; 94(8):2548-54.