Proto-Oncogene Proteins c-cbl
"Proto-Oncogene Proteins c-cbl" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proto-oncogene proteins that negatively regulate RECEPTOR PROTEIN-TYROSINE KINASE signaling. It is a UBIQUITIN-PROTEIN LIGASE and the cellular homologue of ONCOGENE PROTEIN V-CBL.
Descriptor ID |
D050721
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MeSH Number(s) |
D08.811.464.938.750.374 D12.776.624.664.700.172
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Concept/Terms |
Proto-Oncogene Proteins c-cbl- Proto-Oncogene Proteins c-cbl
- Proto Oncogene Proteins c cbl
- c-cbl, Proto-Oncogene Proteins
- RING Finger Protein 55
- c-cbl Protein
- cbl Proto-Oncogene Protein
- Proto-Oncogene Protein, cbl
- cbl Proto Oncogene Protein
- CBL E3 Ubiquitin Protein Ligase
- c-cbl Proto-Oncogene Protein
- Proto-Oncogene Protein, c-cbl
- c cbl Proto Oncogene Protein
- RNF55 Protein
- Proto-Oncogene Protein c-cbl
- Proto Oncogene Protein c cbl
- c-cbl, Proto-Oncogene Protein
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Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins c-cbl".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins c-cbl".
This graph shows the total number of publications written about "Proto-Oncogene Proteins c-cbl" by people in this website by year, and whether "Proto-Oncogene Proteins c-cbl" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2006 | 0 | 1 | 1 |
2009 | 1 | 0 | 1 |
2011 | 1 | 0 | 1 |
2013 | 1 | 0 | 1 |
2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Proto-Oncogene Proteins c-cbl" by people in Profiles.
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The ShcD phosphotyrosine adaptor subverts canonical EGF receptor trafficking. J Cell Sci. 2017 Sep 01; 130(17):2808-2820.
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Receptor tyrosine kinase ubiquitylation involves the dynamic regulation of Cbl-Spry2 by intersectin 1 and the Shp2 tyrosine phosphatase. Mol Cell Biol. 2014 Jan; 34(2):271-9.
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Intersectin 1 enhances Cbl ubiquitylation of epidermal growth factor receptor through regulation of Sprouty2-Cbl interaction. Mol Cell Biol. 2012 Feb; 32(4):817-25.
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Essential role of c-Cbl in amphiregulin-induced recycling and signaling of the endogenous epidermal growth factor receptor. Biochemistry. 2009 Feb 24; 48(7):1462-73.
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Intersectin regulates epidermal growth factor receptor endocytosis, ubiquitylation, and signaling. Mol Pharmacol. 2006 Nov; 70(5):1643-53.