"Spiro Compounds" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cyclic compounds that include two rings which share a single atom (usually a carbon). The simplest example of this type of compound is Spiro[2.2]pentane, which looks like a bow tie.
| Descriptor ID |
D013141
|
| MeSH Number(s) |
D02.455.426.779 D04.711
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Spiro Compounds".
Below are MeSH descriptors whose meaning is more specific than "Spiro Compounds".
This graph shows the total number of publications written about "Spiro Compounds" by people in this website by year, and whether "Spiro Compounds" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 0 | 1 |
| 2005 | 1 | 3 | 4 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Spiro Compounds" by people in Profiles.
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Budget impact and pharmacy costs with targeted use of oliceridine for postsurgical pain in patients at high risk of opioid-related adverse events. Expert Rev Pharmacoecon Outcomes Res. 2022 Jun; 22(4):671-681.
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Cost-effectiveness and cost-benefit analysis of oliceridine in the treatment of acute pain. J Comp Eff Res. 2021 10; 10(15):1107-1119.
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SB-224289 Antagonizes the Antifungal Mechanism of the Marine Depsipeptide Papuamide A. PLoS One. 2016; 11(5):e0154932.
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Thiolates chemically induce redox activation of BTZ043 and related potent nitroaromatic anti-tuberculosis agents. J Am Chem Soc. 2013 Mar 06; 135(9):3539-49.
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Anti-infective discorhabdins from a deep-water alaskan sponge of the genus Latrunculia. J Nat Prod. 2010 Mar 26; 73(3):383-7.
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Transcriptional profiling and inhibition of cholesterol biosynthesis in human T lymphocyte cells by the marine toxin azaspiracid. Genomics. 2008 Mar; 91(3):289-300.
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Effect of NPY5R antagonist MK-0557 on weight regain after very-low-calorie diet-induced weight loss. Obesity (Silver Spring). 2007 Apr; 15(4):895-905.
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The stereocontrolled total synthesis of altohyrtin A/spongistatin 1: the AB-spiroacetal segment. Org Biomol Chem. 2005 Jul 07; 3(13):2399-409.
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The stereocontrolled total synthesis of altohyrtin A/spongistatin 1: fragment couplings, completion of the synthesis, analogue generation and biological evaluation. Org Biomol Chem. 2005 Jul 07; 3(13):2431-40.
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The stereocontrolled total synthesis of altohyrtin A/spongistatin 1: the CD-spiroacetal segment. Org Biomol Chem. 2005 Jul 07; 3(13):2410-9.