"Tunicamycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An N-acetylglycosamine containing antiviral antibiotic obtained from Streptomyces lysosuperificus. It is also active against some bacteria and fungi, because it inhibits the glucosylation of proteins. Tunicamycin is used as tool in the study of microbial biosynthetic mechanisms.
| Descriptor ID |
D014415
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| MeSH Number(s) |
D03.383.742.680.725 D13.570.685.725
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Tunicamycin".
Below are MeSH descriptors whose meaning is more specific than "Tunicamycin".
This graph shows the total number of publications written about "Tunicamycin" by people in this website by year, and whether "Tunicamycin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 1 | 2 |
| 2015 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Tunicamycin" by people in Profiles.
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Glutathione S-Transferase P Influences Redox Homeostasis and Response to Drugs that Induce the Unfolded Protein Response in Zebrafish. J Pharmacol Exp Ther. 2021 04; 377(1):121-132.
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Coordination Analysis of Gene Expression Points to the Relative Impact of Different Regulators During Endoplasmic Reticulum Stress. DNA Cell Biol. 2019 Sep; 38(9):969-981.
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Improvement of chemotherapeutic drug efficacy by endoplasmic reticulum stress. Endocr Relat Cancer. 2015 Apr; 22(2):229-38.
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Essential role of PACT-mediated PKR activation in tunicamycin-induced apoptosis. J Mol Biol. 2009 Jan 16; 385(2):457-68.
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Hepatocyte nuclear factor 4alpha is implicated in endoplasmic reticulum stress-induced acute phase response by regulating expression of cyclic adenosine monophosphate responsive element binding protein H. Hepatology. 2008 Oct; 48(4):1242-50.
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Species diversity of neuronectin and cytotactin expression patterns in the vertebrate central nervous system. Brain Res. 1992 Sep 11; 590(1-2):219-28.
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Reversible ADP-ribosylation of the 78 kDa glucose-regulated protein. FEBS Lett. 1990 Dec 10; 276(1-2):29-33.
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Asparagine-linked oligosaccharides on formyl peptide chemotactic receptors of human phagocytic cells. J Biol Chem. 1985 Feb 25; 260(4):2509-14.