"Lewy Body Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A neurodegenerative disease characterized by dementia, mild parkinsonism, and fluctuations in attention and alertness. The neuropsychiatric manifestations tend to precede the onset of bradykinesia, MUSCLE RIGIDITY, and other extrapyramidal signs. DELUSIONS and visual HALLUCINATIONS are relatively frequent in this condition. Histologic examination reveals LEWY BODIES in the CEREBRAL CORTEX and BRAIN STEM. SENILE PLAQUES and other pathologic features characteristic of ALZHEIMER DISEASE may also be present. (From Neurology 1997;48:376-380; Neurology 1996;47:1113-1124)
| Descriptor ID |
D020961
|
| MeSH Number(s) |
C10.228.140.079.862.400 C10.228.140.380.422 C10.228.662.600.200 C10.574.531 F03.615.400.512
|
| Concept/Terms |
Lewy Body Disease- Lewy Body Disease
- Diffuse Lewy Body Disease
- Lewy Body Dementia
- Cortical Lewy Body Disease
- Lewy Body Disease, Cortical
- Lewy Body Type Senile Dementia
- Lewy Body Disease, Diffuse
- Dementia, Lewy Body
|
Below are MeSH descriptors whose meaning is more general than "Lewy Body Disease".
Below are MeSH descriptors whose meaning is more specific than "Lewy Body Disease".
This graph shows the total number of publications written about "Lewy Body Disease" by people in this website by year, and whether "Lewy Body Disease" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 1 | 2 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 2 | 0 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Lewy Body Disease" by people in Profiles.
-
Dementia with Lewy bodies: Impact of co-pathologies and implications for clinical trial design. Alzheimers Dement. 2023 01; 19(1):318-332.
-
Clinical outcome measures in dementia with Lewy bodies trials: critique and recommendations. Transl Neurodegener. 2022 05 02; 11(1):24.
-
Association of Orthostatic Hypotension With Cerebral Atrophy in Patients With Lewy Body Disorders. Neurology. 2021 08 24; 97(8):e814-e824.
-
Validation of machine learning models to detect amyloid pathologies across institutions. Acta Neuropathol Commun. 2020 04 28; 8(1):59.
-
Acid ?-glucosidase mutants linked to Gaucher disease, Parkinson disease, and Lewy body dementia alter a-synuclein processing. Ann Neurol. 2011 Jun; 69(6):940-53.
-
Dementia with Lewy bodies and Parkinson's disease dementia may best be viewed as two distinct entities. Int Psychogeriatr. 2009 Apr; 21(2):213-6.
-
Neuritic pathology as a correlate of synaptic loss in dementia with lewy bodies. Am J Alzheimers Dis Other Demen. 2008 Feb-Mar; 23(1):97-102.
-
Early-onset dementia: frequency and causes compared to late-onset dementia. Dement Geriatr Cogn Disord. 2006; 21(2):59-64.
-
S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function. Science. 2004 May 28; 304(5675):1328-31.
-
Dementia with Lewy bodies. Lancet Neurol. 2004 Jan; 3(1):19-28.