Immunoglobulin Constant Regions
"Immunoglobulin Constant Regions" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The domains of the immunoglobulin molecules that are invariable in their amino acid sequence within any class or subclass of immunoglobulin. They confer biological as well as structural functions to immunoglobulins. One each on both the light chains and the heavy chains comprises the C-terminus half of the IMMUNOGLOBULIN FAB FRAGMENT and two or three of them make up the rest of the heavy chains (all of the IMMUNOGLOBULIN FC FRAGMENT)
| Descriptor ID |
D007127
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| MeSH Number(s) |
D12.776.124.486.485.538 D12.776.124.790.651.538 D12.776.377.715.548.538
|
| Concept/Terms |
Immunoglobulin Constant Regions- Immunoglobulin Constant Regions
- Constant Regions, Immunoglobulin
- Constant Region, Ig
- Immunoglobulin Constant Region
- Constant Region, Immunoglobulin
|
Below are MeSH descriptors whose meaning is more general than "Immunoglobulin Constant Regions".
Below are MeSH descriptors whose meaning is more specific than "Immunoglobulin Constant Regions".
This graph shows the total number of publications written about "Immunoglobulin Constant Regions" by people in this website by year, and whether "Immunoglobulin Constant Regions" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 0 | 1 |
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 1 | 1 |
| 1999 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "Immunoglobulin Constant Regions" by people in Profiles.
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Nagaoka M, Hagiwara Y, Takemura K, Murakami Y, Li J, Duncan SA, Akaike T. Design of the artificial acellular feeder layer for the efficient propagation of mouse embryonic stem cells. J Biol Chem. 2008 Sep 26; 283(39):26468-76.
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Mancia A, Romano TA, Gefroh HA, Chapman RW, Middleton DL, Warr GW, Lundqvist ML. Characterization of the immunoglobulin A heavy chain gene of the Atlantic bottlenose dolphin (Tursiops truncatus). Vet Immunol Immunopathol. 2007 Aug 15; 118(3-4):304-9.
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Lundqvist ML, McElveen BR, Middleton DL, Chapman R, Warr GW. Evolution of antibody class switching: identification and transcriptional control of an Inu exon in the duck (Anas platyrhynchos). Dev Comp Immunol. 2006; 30(6):575-87.
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Pandey JP, Vedeler CA. Immunoglobulin KM genes in Guillain-Barré syndrome. Neurogenetics. 2003 Apr; 4(3):147-9.
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Bengtén E, Quiniou SM, Stuge TB, Katagiri T, Miller NW, Clem LW, Warr GW, Wilson M. The IgH locus of the channel catfish, Ictalurus punctatus, contains multiple constant region gene sequences: different genes encode heavy chains of membrane and secreted IgD. J Immunol. 2002 Sep 01; 169(5):2488-97.
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Magor KE, Higgins DA, Middleton DL, Warr GW. Opposite orientation of the alpha- and upsilon-chain constant region genes in the immunoglobulin heavy chain locus of the duck. Immunogenetics. 1999 Jul; 49(7-8):692-5.
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Wilson MR, van Ravenstein E, Miller NW, Clem LW, Middleton DL, Warr GW. cDNA sequences and organization of IgM heavy chain genes in two holostean fish. Dev Comp Immunol. 1995 Mar-Apr; 19(2):153-64.
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Cole DJ, Weil DP, Shamamian P, Rivoltini L, Kawakami Y, Topalian S, Jennings C, Eliyahu S, Rosenberg SA, Nishimura MI. Identification of MART-1-specific T-cell receptors: T cells utilizing distinct T-cell receptor variable and joining regions recognize the same tumor epitope. Cancer Res. 1994 Oct 15; 54(20):5265-8.
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Yu JS, Pandey JP, Massacesi L, Lincoln R, Usuku K, Seboun E, Hauser SL. Segregation of immunoglobulin heavy chain constant region genes in multiple sclerosis sibling pairs. J Neuroimmunol. 1993 Jan; 42(1):113-6.
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Kumar A, Martinez-Tarquino C, Maria-Forte A, Kumar P, Alarcon-Segovia D, Granados J, Pandey JP, Buxbaum J, Schur PH. Immunoglobulin heavy chain constant-region gene polymorphism in systemic lupus erythematosus. Arthritis Rheum. 1991 Dec; 34(12):1553-6.