"Lyases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of enzymes that catalyze the cleavage of C-C, C-O, and C-N, and other bonds by other means than by hydrolysis or oxidation. (Enzyme Nomenclature, 1992) EC 4.
Below are MeSH descriptors whose meaning is more general than "Lyases".
Below are MeSH descriptors whose meaning is more specific than "Lyases".
This graph shows the total number of publications written about "Lyases" by people in this website by year, and whether "Lyases" was a major or minor topic of these publications.
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Below are the most recent publications written about "Lyases" by people in Profiles.
Hanigan MH, Townsend DM, Cooper AJ. Metabolism of cisplatin to a nephrotoxin. Toxicology. 2009 Mar 29; 257(3):174-5; author reply 176-7.
Lock EA, Barth JL, Argraves SW, Schnellmann RG. Changes in gene expression in human renal proximal tubule cells exposed to low concentrations of S-(1,2-dichlorovinyl)-l-cysteine, a metabolite of trichloroethylene. Toxicol Appl Pharmacol. 2006 Oct 15; 216(2):319-30.
Peffley DM, Gayen AK. Inhibition of squalene synthase but not squalene cyclase prevents mevalonate-mediated suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase synthesis at a posttranscriptional level. Arch Biochem Biophys. 1997 Jan 15; 337(2):251-60.
Talbot HW, Sumlin AB, Naylor EW, Guthrie R. A neonatal screening test for argininosuccinic acid lyase deficiency and other urea cycle disorders. Pediatrics. 1982 Oct; 70(4):526-31.