"Galactosylceramidase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that hydrolyzes galactose from ceramide monohexosides. Deficiency of this enzyme may cause globoid cell leukodystrophy (LEUKODYSTROPHY, GLOBOID CELL). EC 3.2.1.46.
| Descriptor ID |
D005698
|
| MeSH Number(s) |
D08.811.277.450.410.120
|
| Concept/Terms |
Galactosylceramidase- Galactosylceramidase
- Galactosylcerebroside beta-Galactosidase
- beta-Galactosidase, Galactosylcerebroside
- Galactosylceramide Galactosidase
- Galactosidase, Galactosylceramide
- Galactocerebrosidase
- Galactosylceramide beta-Galactosidase
- beta-Galactosidase, Galactosylceramide
|
Below are MeSH descriptors whose meaning is more general than "Galactosylceramidase".
Below are MeSH descriptors whose meaning is more specific than "Galactosylceramidase".
This graph shows the total number of publications written about "Galactosylceramidase" by people in this website by year, and whether "Galactosylceramidase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2013 | 0 | 2 | 2 |
| 2014 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Galactosylceramidase" by people in Profiles.
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Biochemical, cell biological, pathological, and therapeutic aspects of Krabbe's disease. J Neurosci Res. 2016 11; 94(11):990-1006.
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Effect of vitamin D3 intake on the onset of disease in a murine model of human Krabbe disease. J Neurosci Res. 2015 Jan; 93(1):28-42.
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Tissue-specific effects of saposin A and saposin B on glycosphingolipid degradation in mutant mice. Hum Mol Genet. 2013 Jun 15; 22(12):2435-50.
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Role of endogenous psychosine accumulation in oligodendrocyte differentiation and survival: implication for Krabbe disease. Brain Res. 2013 May 01; 1508:44-52.
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Autonomic denervation of lymphoid organs leads to epigenetic immune atrophy in a mouse model of Krabbe disease. J Neurosci. 2007 Dec 12; 27(50):13730-8.