"Epilepsy, Tonic-Clonic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)
| Descriptor ID |
D004830
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| MeSH Number(s) |
C10.228.140.490.375.290
|
| Concept/Terms |
Epilepsy, Tonic-Clonic- Epilepsy, Tonic-Clonic
- Epilepsies, Tonic-Clonic
- Epilepsy, Tonic Clonic
- Tonic-Clonic Epilepsies
- Tonic-Clonic Epilepsy
- Epilepsy, Grand Mal
- Grand Mal Epilepsy
- Epilepsy, Major
- Major Epilepsies
- Major Epilepsy
- Grand Mal Seizure Disorder
- Major Motor Seizure Disorder
- Tonic-Clonic Seizure Syndrome
- Seizure Syndrome, Tonic-Clonic
- Seizure Syndromes, Tonic-Clonic
- Syndrome, Tonic-Clonic Seizure
- Syndromes, Tonic-Clonic Seizure
- Tonic Clonic Seizure Syndrome
- Tonic-Clonic Seizure Syndromes
- Seizure Disorder, Major Motor
- Seizure Disorder, Tonic Clonic
- Tonic Clonic Convulsions
- Convulsion, Tonic Clonic
- Convulsions, Tonic Clonic
- Tonic Clonic Convulsion
- Tonic-Clonic Convulsion Disorder
- Convulsion Disorder, Tonic-Clonic
- Convulsion Disorders, Tonic-Clonic
- Disorder, Tonic-Clonic Convulsion
- Disorders, Tonic-Clonic Convulsion
- Tonic Clonic Convulsion Disorder
- Tonic-Clonic Convulsion Disorders
- Tonic-Clonic Convulsion Syndrome
- Convulsion Syndrome, Tonic-Clonic
- Convulsion Syndromes, Tonic-Clonic
- Syndrome, Tonic-Clonic Convulsion
- Syndromes, Tonic-Clonic Convulsion
- Tonic Clonic Convulsion Syndrome
- Tonic-Clonic Convulsion Syndromes
- Tonic-Clonic Seizure Disorder
- Disorder, Tonic-Clonic Seizure
- Disorders, Tonic-Clonic Seizure
- Seizure Disorder, Tonic-Clonic
- Seizure Disorders, Tonic-Clonic
- Tonic Clonic Seizure Disorder
- Tonic-Clonic Seizure Disorders
- Convulsions, Grand Mal
- Convulsion, Grand Mal
- Grand Mal Convulsion
- Grand Mal Convulsions
- Seizure Disorder, Grand Mal
Epilepsy, Tonic-Clonic, Symptomatic- Epilepsy, Tonic-Clonic, Symptomatic
- Symptomatic Tonic-Clonic Epilepsy
- Epilepsies, Symptomatic Tonic-Clonic
- Epilepsy, Symptomatic Tonic-Clonic
- Symptomatic Tonic Clonic Epilepsy
- Symptomatic Tonic-Clonic Epilepsies
- Tonic-Clonic Epilepsies, Symptomatic
- Tonic-Clonic Epilepsy, Symptomatic
Cryptogenic Tonic-Clonic Epilepsy- Cryptogenic Tonic-Clonic Epilepsy
- Cryptogenic Tonic Clonic Epilepsy
- Cryptogenic Tonic-Clonic Epilepsies
- Epilepsies, Cryptogenic Tonic-Clonic
- Epilepsy, Cryptogenic Tonic-Clonic
- Tonic-Clonic Epilepsies, Cryptogenic
- Tonic-Clonic Epilepsy, Cryptogenic
- Epilepsy, Tonic-Clonic, Cryptogenic
Epilepsy, Tonic-Clonic, Familial- Epilepsy, Tonic-Clonic, Familial
- Familial Tonic-Clonic Epilepsy
- Epilepsies, Familial Tonic-Clonic
- Epilepsy, Familial Tonic-Clonic
- Familial Tonic Clonic Epilepsy
- Familial Tonic-Clonic Epilepsies
- Tonic-Clonic Epilepsies, Familial
- Tonic-Clonic Epilepsy, Familial
|
Below are MeSH descriptors whose meaning is more general than "Epilepsy, Tonic-Clonic".
Below are MeSH descriptors whose meaning is more specific than "Epilepsy, Tonic-Clonic".
This graph shows the total number of publications written about "Epilepsy, Tonic-Clonic" by people in this website by year, and whether "Epilepsy, Tonic-Clonic" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 1 | 2 |
| 2009 | 0 | 1 | 1 |
| 2017 | 1 | 1 | 2 |
| 2018 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Epilepsy, Tonic-Clonic" by people in Profiles.
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Tucker Price S, DeCastro AO, Brock CD. Post-concussion syndrome and pre-existing mood disorder: A case report. Int J Psychiatry Med. 2019 05; 54(3):163-171.
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Halford JJ, Sperling MR, Nair DR, Dlugos DJ, Tatum WO, Harvey J, French JA, Pollard JR, Faught E, Noe KH, Henry TR, Jetter GM, Lie OV, Morgan LC, Girouard MR, Cardenas DP, Whitmire LE, Cavazos JE. Detection of generalized tonic-clonic seizures using surface electromyographic monitoring. Epilepsia. 2017 11; 58(11):1861-1869.
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Jobst BC, Kapur R, Barkley GL, Bazil CW, Berg MJ, Bergey GK, Boggs JG, Cash SS, Cole AJ, Duchowny MS, Duckrow RB, Edwards JC, Eisenschenk S, Fessler AJ, Fountain NB, Geller EB, Goldman AM, Goodman RR, Gross RE, Gwinn RP, Heck C, Herekar AA, Hirsch LJ, King-Stephens D, Labar DR, Marsh WR, Meador KJ, Miller I, Mizrahi EM, Murro AM, Nair DR, Noe KH, Olejniczak PW, Park YD, Rutecki P, Salanova V, Sheth RD, Skidmore C, Smith MC, Spencer DC, Srinivasan S, Tatum W, Van Ness P, Vossler DG, Wharen RE, Worrell GA, Yoshor D, Zimmerman RS, Skarpaas TL, Morrell MJ. Brain-responsive neurostimulation in patients with medically intractable seizures arising from eloquent and other neocortical areas. Epilepsia. 2017 06; 58(6):1005-1014.
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Kellner CH, Fink M. Electroconvulsive therapy in the treatment of intractable status epilepticus. Epilepsy Behav. 2009 Sep; 16(1):189-90; author reply 191.
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Shanske AL, Shanske S, Silvestri G, Tanji K, Wertheim D, Lipper S. MELAS point mutation with unusual clinical presentation. Neuromuscul Disord. 1993 May; 3(3):191-3.
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Pritchett JT, Kellner CH. Comment on spontaneous seizure activity. J Nerv Ment Dis. 1993 Feb; 181(2):138-40.
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Eyanson S, Passo MH, Aldo-Benson MA, Benson MD. Methylprednisolone pulse therapy for nonrenal lupus erythematosus. Ann Rheum Dis. 1980 Aug; 39(4):377-80.
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Wood JH, Hare TA, Glaeser BS, Ballenger JC, Post RM. Low cerebrospinal fluid gamma-aminobutyric acid content in seizure patients. Neurology. 1979 Sep; 29(9 Pt 1):1203-8.