Activating Transcription Factor 4
"Activating Transcription Factor 4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An activating transcription factor that regulates the expression of a variety of GENES involved in amino acid metabolism and transport. It also interacts with HTLV-I transactivator protein.
| Descriptor ID |
D051701
|
| MeSH Number(s) |
D12.776.260.108.061.937 D12.776.930.127.061.937
|
| Concept/Terms |
Activating Transcription Factor 4- Activating Transcription Factor 4
- ATF4 Transcription Factor
- Transcription Factor, ATF4
- Tax-Responsive Enhancer Element B67
- Tax Responsive Enhancer Element B67
|
Below are MeSH descriptors whose meaning is more general than "Activating Transcription Factor 4".
Below are MeSH descriptors whose meaning is more specific than "Activating Transcription Factor 4".
This graph shows the total number of publications written about "Activating Transcription Factor 4" by people in this website by year, and whether "Activating Transcription Factor 4" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Activating Transcription Factor 4" by people in Profiles.
-
Glutathione S-Transferase P Influences Redox Homeostasis and Response to Drugs that Induce the Unfolded Protein Response in Zebrafish. J Pharmacol Exp Ther. 2021 04; 377(1):121-132.
-
Stress relief for cancer immunotherapy: implications for the ER stress response in tumor immunity. Cancer Immunol Immunother. 2021 May; 70(5):1165-1175.
-
ER stress-induced mediator C/EBP homologous protein thwarts effector T?cell activity in tumors through T-bet repression. Nat Commun. 2019 03 20; 10(1):1280.
-
ATF4-dependent induction of heme oxygenase 1 prevents anoikis and promotes metastasis. J Clin Invest. 2015 Jul 01; 125(7):2592-608.
-
Identification and characterization of a potent activator of p53-independent cellular senescence via a small-molecule screen for modifiers of the integrated stress response. Mol Pharmacol. 2013 Mar; 83(3):594-604.
-
miR-211 is a prosurvival microRNA that regulates chop expression in a PERK-dependent manner. Mol Cell. 2012 Nov 09; 48(3):353-64.
-
The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation. EMBO J. 2010 Jun 16; 29(12):2082-96.
-
Hypoxic reactive oxygen species regulate the integrated stress response and cell survival. J Biol Chem. 2008 Nov 07; 283(45):31153-62.