"Angiostatins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Circulating 38-kDa proteins that are internal peptide fragments of PLASMINOGEN. The name derives from the fact that they are potent ANGIOGENESIS INHIBITORS. Angiostatins contain four KRINGLE DOMAINS which are associated with their potent angiostatic activity.
| Descriptor ID |
D043168
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| MeSH Number(s) |
D08.622.610.500 D12.644.276.100.450.500 D12.776.124.790.223.580.500 D12.776.377.715.182.580.500 D12.776.467.100.450.500 D23.529.100.450.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Angiostatins".
Below are MeSH descriptors whose meaning is more specific than "Angiostatins".
This graph shows the total number of publications written about "Angiostatins" by people in this website by year, and whether "Angiostatins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
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Below are the most recent publications written about "Angiostatins" by people in Profiles.
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Macrophage elastase (matrix metalloproteinase-12) suppresses growth of lung metastases. Cancer Res. 2006 Jun 15; 66(12):6149-55.
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Thalidomide and angiostatin inhibit tumor growth in a murine xenograft model of human cervical cancer. Gynecol Oncol. 2005 Aug; 98(2):203-10.
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The effect of angiostatin on vascular leakage and VEGF expression in rat retina. FEBS Lett. 2004 Apr 23; 564(1-2):19-23.