Drug Combinations

"Drug Combinations" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Single preparations containing two or more active agents, for the purpose of their concurrent administration as a fixed dose mixture.

Descriptor ID	D004338
MeSH Number(s)	D26.310
Concept/Terms	Drug Combinations Drug Combinations Combinations, Drug

Below are MeSH descriptors whose meaning is more general than "Drug Combinations".

Chemicals and Drugs [D]
Pharmaceutical Preparations [D26]
Drug Combinations [D26.310]

Below are MeSH descriptors whose meaning is more specific than "Drug Combinations".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Drug Combinations" by people in this website by year, and whether "Drug Combinations" was a major or minor topic of these publications.

Bar chart showing 229 publications over 31 distinct years, with a maximum of 18 publications in 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1992	0	2	2
1993	0	1	1
1994	0	2	2
1995	0	1	1
1996	0	3	3
1997	1	3	4
1998	0	1	1
1999	0	5	5
2000	0	3	3
2001	0	4	4
2002	0	5	5
2003	0	8	8
2004	0	5	5
2005	0	7	7
2006	0	8	8
2007	1	9	10
2008	0	9	9
2009	0	7	7
2010	0	10	10
2011	0	7	7
2012	0	6	6
2013	0	10	10
2014	0	13	13
2015	0	11	11
2016	0	15	15
2017	0	11	11
2018	0	11	11
2019	2	13	15
2020	0	18	18
2021	0	13	13
2022	0	4	4

Below are the most recent publications written about "Drug Combinations" by people in Profiles.

Egan BM, Kjeldsen SE, Narkiewicz K, Kreutz R, Burnier M. Single-pill combinations, hypertension control and clinical outcomes: potential, pitfalls and solutions. Blood Press. 2022 12; 31(1):164-168.

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Samuvel DJ, Nguyen NT, Jaeschke H, Lemasters JJ, Wang X, Choo YM, Hamann MT, Zhong Z. Platanosides, a Potential Botanical Drug Combination, Decrease Liver Injury Caused by Acetaminophen Overdose in Mice. J Nat Prod. 2022 07 22; 85(7):1779-1788.

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Curtain JP, Jackson AM, Shen L, Jhund PS, Docherty KF, Petrie MC, Castagno D, Desai AS, Rohde LE, Lefkowitz MP, Rouleau JL, Zile MR, Solomon SD, Swedberg K, Packer M, McMurray JJV. Effect of sacubitril/valsartan on investigator-reported ventricular arrhythmias in PARADIGM-HF. Eur J Heart Fail. 2022 03; 24(3):551-561.

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Mc Causland FR, Lefkowitz MP, Claggett B, Packer M, Senni M, Gori M, Jhund PS, McGrath MM, Rouleau JL, Shi V, Swedberg K, Vaduganathan M, Zannad F, Pfeffer MA, Zile M, McMurray JJV, Solomon SD. Angiotensin-neprilysin inhibition and renal outcomes across the spectrum of ejection fraction in heart failure. Eur J Heart Fail. 2022 Sep; 24(9):1591-1598.

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Stein Gold L, Baldwin H, Kircik LH, Weiss JS, Pariser DM, Callender V, Lain E, Gold M, Beer K, Draelos Z, Sadick N, Pillai R, Bhatt V, Tanghetti EA. Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug. Am J Clin Dermatol. 2022 Jan; 23(1):93-104.

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Jackson AM, Jhund PS, Anand IS, Düngen HD, Lam CSP, Lefkowitz MP, Linssen G, Lund LH, Maggioni AP, Pfeffer MA, Rouleau JL, Saraiva JFK, Senni M, Vardeny O, Wijkman MO, Yilmaz MB, Saito Y, Zile MR, Solomon SD, McMurray JJV. Sacubitril-valsartan as a treatment for apparent resistant hypertension in patients with heart failure and preserved ejection fraction. Eur Heart J. 2021 09 21; 42(36):3741-3752.

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Gori M, Senni M, Claggett B, Liu J, Maggioni AP, Zile M, Prescott MF, Van Veldhuisen DJ, Zannad F, Pieske B, Lam CSP, Rouleau J, Jhund P, Packer M, Pfeffer MA, Lefkowitz M, Shi V, McMurray JJV, Solomon SD. Integrating High-Sensitivity Troponin T and Sacubitril/Valsartan Treatment in HFpEF: The PARAGON-HF Trial. JACC Heart Fail. 2021 09; 9(9):627-635.

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Suzuki K, Claggett B, Minamisawa M, Packer M, Zile MR, Pfeffer MA, Chiang LM, Lefkowitz M, McMurray JJV, Solomon SD, Desai AS. Influence of study discontinuation during the run-in period on the estimated efficacy of sacubitril/valsartan in the PARAGON-HF trial. Eur J Heart Fail. 2021 12; 23(12):2085-2090.

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Bhatt AS, Vaduganathan M, Claggett BL, Liu J, Packer M, Desai AS, Lefkowitz MP, Rouleau JL, Shi VC, Zile MR, Swedberg K, Vardeny O, McMurray JJV, Solomon SD. Effect of sacubitril/valsartan vs. enalapril on changes in heart failure therapies over time: the PARADIGM-HF trial. Eur J Heart Fail. 2021 09; 23(9):1518-1524.

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Bhatt AS, Claggett BL, Packer M, Lefkowitz MP, Zile MR, McMurray JJV, Solomon SD, Vaduganathan M. Treatment Effects of Sacubitril/Valsartan Compared With Valsartan by Ejection Fraction in Patients With Recent Hospitalization. J Card Fail. 2021 09; 27(9):1027-1030.

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