Pierre Giglio

Title
InstitutionMedical University of South Carolina
DepartmentNeurosurgery
AddressP.O. Box MSC 606
313F CSB
96 Jonathan Lucas St.
Phone843-792-6592
Fax843-792-8623
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    Brain Tumor, Cancer, Men-s Health, Women-s Health

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Matsui JK, Perlow HK, Ritter AR, Upadhyay R, Raval RR, Thomas EM, Beyer SJ, Pillainayagam C, Goranovich J, Ong S, Giglio P, Palmer JD. Small Molecules and Immunotherapy Agents for Enhancing Radiotherapy in Glioblastoma. Biomedicines. 2022 Jul 21; 10(7). PMID: 35885067.
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    2. Kreatsoulas D, Bolyard C, Wu BX, Cam H, Giglio P, Li Z. Translational landscape of glioblastoma immunotherapy for physicians: guiding clinical practice with basic scientific evidence. J Hematol Oncol. 2022 06 11; 15(1):80. PMID: 35690784.
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    3. Lassman AB, Sepúlveda-Sánchez JM, Cloughesy TF, Gil-Gil MJ, Puduvalli VK, Raizer JJ, De Vos FYF, Wen PY, Butowski NA, Clement PMJ, Groves MD, Belda-Iniesta C, Giglio P, Soifer HS, Rowsey S, Xu C, Avogadri F, Wei G, Moran S, Roth P. Infigratinib in Patients with Recurrent Gliomas and FGFR Alterations: A Multicenter Phase II Study. Clin Cancer Res. 2022 06 01; 28(11):2270-2277. PMID: 35344029.
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    4. Wang W, Howard D, Giglio P, Thomas D, Javier Otero J. Bioethical implications of current state practices of molecular diagnostics in neuropathology. Neuro Oncol. 2022 06 01; 24(6):853-854. PMID: 35381085.
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    5. Palmer JD, Prasad RN, Fabian D, Wei L, Yildiz VO, Tan Y, Grecula J, Welliver M, Williams T, Elder JB, Raval R, Blakaj D, Haglund K, Bazan J, Kendra K, Arnett A, Beyer S, Liebner D, Giglio P, Puduvalli V, Chakravarti A, Wuthrick E. Phase I study of trametinib in combination with whole brain radiation therapy for brain metastases. Radiother Oncol. 2022 05; 170:21-26. PMID: 35367525.
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    6. Perlow HK, Yaney A, Yang M, Klamer B, Matsui J, Raval RR, Blakaj DM, Arnett A, Beyer S, Elder JB, Ammirati M, Lonser R, Hardesty D, Ong S, Giglio P, Pillainayagam C, Goranovich J, Grecula J, Chakravarti A, Gondi V, Brown PD, Palmer JD. Dose-escalated accelerated hypofractionation for elderly or frail patients with a newly diagnosed glioblastoma. J Neurooncol. 2022 Jan; 156(2):399-406. PMID: 35013838.
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    7. Rayi A, Alnahhas I, Ong S, Giglio P, Puduvalli VK. Targeted Therapy for BRAF Mutant Brain Tumors. Curr Treat Options Oncol. 2021 10 06; 22(11):105. PMID: 34613491.
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    8. Rinehardt H, Kassem M, Morgan E, Palettas M, Stephens JA, Suresh A, Ganju A, Lustberg M, Wesolowski R, Sardesai S, Stover D, Vandeusen J, Cherian M, Prieto Eibl MDPG, Miah A, Alnahhas I, Giglio P, Puduvalli VK, Ramaswamy B, Williams N, Noonan AM. Assessment of Leptomeningeal Carcinomatosis Diagnosis, Management and Outcomes in Patients with Solid Tumors Over a Decade of Experience. Eur J Breast Health. 2021 Oct; 17(4):371-377. PMID: 34651117.
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    9. Alnahhas I, Rayi A, Guillermo Prieto Eibl MDP, Ong S, Giglio P, Puduvalli V. Prognostic implications of epidermal and platelet-derived growth factor receptor alterations in 2 cohorts of IDHwt glioblastoma. Neurooncol Adv. 2021 Jan-Dec; 3(1):vdab127. PMID: 34667950.
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    10. Huntoon K, Makary MS, Damante M, Giglio P, Slone W, Elder JB. Intraoperative 3 T MRI is more correlative to residual disease extent than early postoperative MRI. J Neurooncol. 2021 Sep; 154(3):345-351. PMID: 34417709.
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    11. Alnahhas I, Alsawas M, Rayi A, Palmer JD, Raval R, Ong S, Giglio P, Murad MH, Puduvalli V. Erratum to: Characterizing Benefit from Temozolomide in MGMT Promoter Unmethylated and Methylated Glioblastoma: A Systematic Review and Meta-analysis. Neurooncol Adv. 2021 Jan-Dec; 3(1):vdab095. PMID: 34258581.
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    12. Einstein EH, Bonda D, Hosseini H, Harel A, Palmer JD, Giglio P, Barve R, Gould M, Lonser RR, D'Amico RS. Large Adult Spinal Diffuse Midline Histone H3 Lysine27-to-Methionine-Mutant Glioma With Intramedullary and Extramedullary Components Presenting With Progressive Hydrocephalus: A Case Report Highlighting Unique Imaging Findings and Treatment. Cureus. 2021 May; 13(5):e15333. PMID: 34235012.
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    13. Eltobgy M, Huntoon K, Musgrave N, Shaikhouni A, Hardesty DA, Giglio P, Elder JB. Impact of cerebrospinal fluid flow study in patients undergoing intrathecal chemotherapy via ventricular catheter reservoir. J Neurooncol. 2021 May; 153(1):161-167. PMID: 33860429.
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    14. Alnahhas I, Rayi A, Ong S, Giglio P, Puduvalli V. Management of gliomas in patients with Lynch syndrome. Neuro Oncol. 2021 01 30; 23(1):167-168. PMID: 33059358.
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    15. Wang JL, Barth RF, Cavaliere R, Puduvalli VK, Giglio P, Lonser RR, Elder JB. Phase I trial of intracerebral convection-enhanced delivery of carboplatin for treatment of recurrent high-grade gliomas. PLoS One. 2020; 15(12):e0244383. PMID: 33373402.
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    16. Alnahhas I, LaHaye S, Giglio P, Mardis E, Puduvalli V. An evaluation of MGMT promoter methylation within the methylation subclasses of glioblastoma. Neurooncol Adv. 2020 Jan-Dec; 2(1):vdaa117. PMID: 33880446.
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    17. Alnahhas I, Rayi A, Thomas D, Ong S, Giglio P, Puduvalli V. False-positive 1p/19q Testing Results in Gliomas: Clinical and Research Consequences. Am J Clin Oncol. 2020 11; 43(11):802-805. PMID: 32889892.
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    18. Alnahhas I, Alsawas M, Rayi A, Palmer JD, Raval R, Ong S, Giglio P, Murad MH, Puduvalli V. Characterizing benefit from temozolomide in MGMT promoter unmethylated and methylated glioblastoma: a systematic review and meta-analysis. Neurooncol Adv. 2020 Jan-Dec; 2(1):vdaa082. PMID: 33150334.
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    19. Alnahhas I, Rayi A, Palmer JD, Raval R, Folefac E, Ong S, Giglio P, Puduvalli V. The role of VEGF receptor inhibitors in preventing cerebral radiation necrosis: a retrospective cohort study. Neurooncol Pract. 2021 Feb; 8(1):75-80. PMID: 33664972.
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    20. Puduvalli VK, Wu J, Yuan Y, Armstrong TS, Vera E, Wu J, Xu J, Giglio P, Colman H, Walbert T, Raizer J, Groves MD, Tran D, Iwamoto F, Avgeropoulos N, Paleologos N, Fink K, Peereboom D, Chamberlain M, Merrell R, Penas Prado M, Yung WKA, Gilbert MR. A Bayesian adaptive randomized phase II multicenter trial of bevacizumab with or without vorinostat in adults with recurrent glioblastoma. Neuro Oncol. 2020 10 14; 22(10):1505-1515. PMID: 32166308.
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    21. Freeman T, Legasto CS, Schickli MA, McLaughlin EM, Giglio P, Puduvalli V, Gonzalez J. High-dose methotrexate-based regimens with or without vincristine for the treatment of primary central nervous system lymphoma. Neurooncol Adv. 2020 Jan-Dec; 2(1):vdaa077. PMID: 32715297.
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    22. Makary MS, Kobalka P, Giglio P, Slone HW. Meningioangiomatosis: Clinical, Imaging, and Histopathologic Characteristics. J Clin Imaging Sci. 2020; 10:36. PMID: 32637227.
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    23. Lee CY, Kalra A, Spampinato MV, Tabesh A, Jensen JH, Helpern JA, de Fatima Falangola M, Van Horn MH, Giglio P. Early assessment of recurrent glioblastoma response to bevacizumab treatment by diffusional kurtosis imaging: a preliminary report. Neuroradiol J. 2019 Oct; 32(5):317-327. PMID: 31282311.
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    24. Carpenter CD, Alnahhas I, Gonzalez J, Giglio P, Puduvalli VK. Changing paradigms for targeted therapies against diffuse infiltrative gliomas: tackling a moving target. Expert Rev Neurother. 2019 07; 19(7):663-677. PMID: 31106606.
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    25. Dornbos D, Elder JB, Otero JJ, Baiocchi RA, Slone HW, Puduvalli VK, Giglio P. Spinal Cord Toxicity from Intrathecal Chemotherapy: A Case with Clinicopathologic Correlation. World Neurosurg. 2019 Aug; 128:381-384. PMID: 31128312.
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    26. Fabian D, Guillermo Prieto Eibl MDP, Alnahhas I, Sebastian N, Giglio P, Puduvalli V, Gonzalez J, Palmer JD. Treatment of Glioblastoma (GBM) with the Addition of Tumor-Treating Fields (TTF): A Review. Cancers (Basel). 2019 Feb 02; 11(2). PMID: 30717372.
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    27. Das A, Henderson F, Lowe S, Wallace GC, Vandergrift WA, Lindhorst SM, Varma AK, Infinger LK, Giglio P, Banik NL, Patel SJ, Cachia D. Single agent efficacy of the HDAC inhibitor DATS in preclinical models of glioblastoma. Cancer Chemother Pharmacol. 2018 12; 82(6):945-952. PMID: 30209569.
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    28. Yazdani M, Rumboldt Z, Tabesh A, Giglio P, Schiarelli C, Morgan PS, Spampinato MV. Perilesional apparent diffusion coefficient in the preoperative evaluation of glioma grade. Clin Imaging. 2018 Nov - Dec; 52:88-94. PMID: 30032069.
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    29. Das A, Cheng RR, Hilbert ML, Dixon-Moh YN, Decandio M, Vandergrift WA, Banik NL, Lindhorst SM, Cachia D, Varma AK, Patel SJ, Giglio P. Synergistic Effects of Crizotinib and Temozolomide in Experimental FIG-ROS1 Fusion-Positive Glioblastoma. Cancer Growth Metastasis. 2015; 8:51-60. PMID: 26648752.
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    30. Das A, Miller R, Lee P, Holden CA, Lindhorst SM, Jaboin J, Vandergrift WA, Banik NL, Giglio P, Varma AK, Raizer JJ, Patel SJ. A novel component from citrus, ginger, and mushroom family exhibits antitumor activity on human meningioma cells through suppressing the Wnt/ß-catenin signaling pathway. Tumour Biol. 2015 Sep; 36(9):7027-34. PMID: 25864108.
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    31. Lee P, Murphy B, Miller R, Menon V, Banik NL, Giglio P, Lindhorst SM, Varma AK, Vandergrift WA, Patel SJ, Das A. Mechanisms and clinical significance of histone deacetylase inhibitors: epigenetic glioblastoma therapy. Anticancer Res. 2015 Feb; 35(2):615-25. PMID: 25667438.
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    32. Penas-Prado M, Hess KR, Fisch MJ, Lagrone LW, Groves MD, Levin VA, De Groot JF, Puduvalli VK, Colman H, Volas-Redd G, Giglio P, Conrad CA, Salacz ME, Floyd JD, Loghin ME, Hsu SH, Gonzalez J, Chang EL, Woo SY, Mahajan A, Aldape KD, Yung WK, Gilbert MR. Randomized phase II adjuvant factorial study of dose-dense temozolomide alone and in combination with isotretinoin, celecoxib, and/or thalidomide for glioblastoma. Neuro Oncol. 2015 Feb; 17(2):266-73. PMID: 25239666.
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    33. Agrawal NS, Miller R, Lal R, Mahanti H, Dixon-Mah YN, DeCandio ML, Vandergrift WA, Varma AK, Patel SJ, Banik NL, Lindhorst SM, Giglio P, Das A. Current Studies of Immunotherapy on Glioblastoma. J Neurol Neurosurg. 2014 Apr 05; 1(1). PMID: 25346943.
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    34. Miller R, DeCandio ML, Dixon-Mah Y, Giglio P, Vandergrift WA, Banik NL, Patel SJ, Varma AK, Das A. Molecular Targets and Treatment of Meningioma. J Neurol Neurosurg. 2014; 1(1). PMID: 25485306.
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    35. Wallace GC, Haar CP, Vandergrift WA, Giglio P, Dixon-Mah YN, Varma AK, Ray SK, Patel SJ, Banik NL, Das A. Multi-targeted DATS prevents tumor progression and promotes apoptosis in ectopic glioblastoma xenografts in SCID mice via HDAC inhibition. J Neurooncol. 2013 Aug; 114(1):43-50. PMID: 23754639.
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    36. Wallace GC, Dixon-Mah YN, Vandergrift WA, Ray SK, Haar CP, Mittendorf AM, Patel SJ, Banik NL, Giglio P, Das A. Targeting oncogenic ALK and MET: a promising therapeutic strategy for glioblastoma. Metab Brain Dis. 2013 Sep; 28(3):355-66. PMID: 23543207.
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    37. Galloway SK, Baker M, Giglio P, Chin S, Madan A, Malcolm R, Serber ER, Wedin S, Balliet W, Borckardt J. Depression and Anxiety Symptoms Relate to Distinct Components of Pain Experience among Patients with Breast Cancer. Pain Res Treat. 2012; 2012:851276. PMID: 23227331.
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    38. Haar CP, Hebbar P, Wallace GC, Das A, Vandergrift WA, Smith JA, Giglio P, Patel SJ, Ray SK, Banik NL. Drug resistance in glioblastoma: a mini review. Neurochem Res. 2012 Jun; 37(6):1192-200. PMID: 22228201.
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    39. Giglio P, Dhamne M, Hess KR, Gilbert MR, Groves MD, Levin VA, Kang SL, Ictech SE, Liu V, Colman H, Conrad CA, Loghin M, de Groot J, Yung WK, Puduvalli VK. Phase 2 trial of irinotecan and thalidomide in adults with recurrent anaplastic glioma. Cancer. 2012 Jul 15; 118(14):3599-606. PMID: 22086614.
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    40. Nozaki K, Silver RM, Stickler DE, Abou-Fayssal NG, Giglio P, Kamen DL, Daniel R, Judson MA. Neurological deficits during treatment with tumor necrosis factor-alpha antagonists. Am J Med Sci. 2011 Nov; 342(5):352-5. PMID: 21876428.
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    41. Vargas J, Gowans M, Vandergrift WA, Hope J, Giglio P. Metastatic hepatocellular carcinoma with associated spinal cord compression. Am J Med Sci. 2011 Feb; 341(2):148-52. PMID: 21107234.
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    42. Ruppert B, Welsh CT, Hannah J, Giglio P, Rumboldt Z, Johnson I, Fortney J, Jenrette JM, Patel S, Scheithauer BW. Glioneuronal tumor with neuropil-like islands of the spinal cord with diffuse leptomeningeal neuraxis dissemination. J Neurooncol. 2011 Sep; 104(2):529-33. PMID: 21188469.
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    43. Shukla BS, Giglio P, Couch JE, Hasija N, Krishna V, Frankel BM, Welsh CT. Concomitant lymphoma and cryptococcosis in a patient with acquired immune deficiency syndrome. Am J Med Sci. 2010 Oct; 340(4):340-2. PMID: 20739871.
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    44. Gilbert MR, Gonzalez J, Hunter K, Hess K, Giglio P, Chang E, Puduvalli V, Groves MD, Colman H, Conrad C, Levin V, Woo S, Mahajan A, de Groot J, Yung WK. A phase I factorial design study of dose-dense temozolomide alone and in combination with thalidomide, isotretinoin, and/or celecoxib as postchemoradiation adjuvant therapy for newly diagnosed glioblastoma. Neuro Oncol. 2010 Nov; 12(11):1167-72. PMID: 20729242.
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    45. Giglio P, Villano JL. Newly diagnosed high-grade gliomas. Curr Treat Options Neurol. 2010 Jul; 12(4):309-20. PMID: 20842590.
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    46. Matmati K, Matmati N, Hannun YA, Rumboldt Z, Patel S, Lazarchick J, Stuart R, Giglio P. Dural MALT lymphoma with disseminated disease. Hematol Rep. 2010 Jan 26; 2(1):e10. PMID: 22184513.
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    47. Giglio P, Gilbert MR. Neurologic complications of cancer and its treatment. Curr Oncol Rep. 2010 Jan; 12(1):50-9. PMID: 20425608.
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    48. Watkins JM, Marshall DT, Patel S, Giglio P, Herrin AE, Garrett-Mayer E, Jenrette JM. High-dose radiotherapy to 78 Gy with or without temozolomide for high grade gliomas. J Neurooncol. 2009 Jul; 93(3):343-8. PMID: 19142584.
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    49. Hazin R, Abuzetun JY, Giglio P, Khan F. Agrypnia excitata: current concepts and future prospects in management. J Neuropsychiatry Clin Neurosci. 2009; 21(2):126-31. PMID: 19622683.
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    50. Puduvalli VK, Giglio P, Groves MD, Hess KR, Gilbert MR, Mahankali S, Jackson EF, Levin VA, Conrad CA, Hsu SH, Colman H, de Groot JF, Ritterhouse MG, Ictech SE, Yung WK. Phase II trial of irinotecan and thalidomide in adults with recurrent glioblastoma multiforme. Neuro Oncol. 2008 Apr; 10(2):216-22. PMID: 18314417.
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    51. Attard TM, Giglio P, Koppula S, Snyder C, Lynch HT. Brain tumors in individuals with familial adenomatous polyposis: a cancer registry experience and pooled case report analysis. Cancer. 2007 Feb 15; 109(4):761-6. PMID: 17238184.
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    52. Giglio P, Gilbert MR. Neurologic complications of non-Hodgkin's lymphoma. Curr Hematol Malig Rep. 2006 Dec; 1(4):214-9. PMID: 20425316.
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    53. Giglio P, Bednarczyk EM, Weiss K, Bakshi R. Syncope and head CT scans in the emergency department. Emerg Radiol. 2005 Dec; 12(1-2):44-6. PMID: 16292675.
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    54. Bierman P, Giglio P. Diagnosis and treatment of central nervous system involvement in non-Hodgkin's lymphoma. Hematol Oncol Clin North Am. 2005 Aug; 19(4):597-609, v. PMID: 16083825.
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    55. Giglio P, Weinberg JS, Forman AD, Wolff R, Groves MD. Neoplastic meningitis in patients with adenocarcinoma of the gastrointestinal tract. Cancer. 2005 Jun 01; 103(11):2355-62. PMID: 15856426.
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    56. Giglio P, Undevia N, Spire JP. The primary parasomnias. A review for neurologists. Neurologist. 2005 Mar; 11(2):90-7. PMID: 15733331.
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    57. Giglio P, Gilbert MR. Neurologic complications of non-Hodgkin's lymphoma. Curr Oncol Rep. 2005 Jan; 7(1):61-5. PMID: 15610688.
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    58. Giglio P. Case 3: kicking, yelling and sleeping. MedGenMed. 2004 Oct 05; 6(4):43. PMID: 15775870.
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    59. Giglio P, Undevia N, Spire JP. Case 2: an irresistible urge to sleep. MedGenMed. 2004 Aug 31; 6(3):45. PMID: 15520669.
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    60. Undevia N, Giglio P, Spire JP. Case files from the University of Chicago's Sleep Disorders Center. Case 1: a gigantic fatigue. MedGenMed. 2004 Apr 02; 6(2):50. PMID: 15266275.
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    61. Giglio P, Levin V. Cyclooxygenase-2 inhibitors in glioma therapy. Am J Ther. 2004 Mar-Apr; 11(2):141-3. PMID: 14999366.
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    62. Giglio P, Tremont-Lukats IW, Groves MD. Response of neoplastic meningitis from solid tumors to oral capecitabine. J Neurooncol. 2003 Nov; 65(2):167-72. PMID: 14686737.
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    63. Weinstock A, Giglio P, Kerr SL, Duffner PK, Cohen ME. Hyperkinetic seizures in children. J Child Neurol. 2003 Aug; 18(8):517-24. PMID: 13677576.
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    64. Giglio P, Gilbert MR. Cerebral radiation necrosis. Neurologist. 2003 Jul; 9(4):180-8. PMID: 12864928.
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    65. Giglio P. Toxic epidermal necrolysis due to administration of celecoxib (Celebrex). South Med J. 2003 Mar; 96(3):320-1. PMID: 12659372.
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    66. Tremont-Lukats IW, Fuller GN, Ribalta T, Giglio P, Groves MD. Paraneoplastic chorea: case study with autopsy confirmation. Neuro Oncol. 2002 07; 4(3):192-5. PMID: 12084350.
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    67. Giglio P, Bakshi R, Block S, Ostrow P, Pullicino PM. Primary central nervous system lymphoma masquerading as herpes encephalitis: clinical, magnetic resonance imaging, and pathologic findings. Am J Med Sci. 2002 Jan; 323(1):59-61. PMID: 11814145.
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    68. Ionita C, Giglio P, Isayev E, Alberico R, Pullicino P. Paradoxical brain embolism from thrombus associated with vena caval filter in a patient with cancer. J Neuroimaging. 2002 Jan; 12(1):69-71. PMID: 11826603.
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    69. Weinstock A, Giglio P, Cohen ME, Bakshi R, Januario J, Balos L. Diffuse magnetic resonance imaging white-matter changes in a 15-year-old boy with mitochondrial encephalomyopathy. J Child Neurol. 2002 Jan; 17(1):47-9. PMID: 11913571.
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    70. Orr RK, Hoehn JL, Col NF. The learning curve for sentinel node biopsy in breast cancer: practical considerations. Arch Surg. 1999 Jul; 134(7):764-7. PMID: 26684801.
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