Devadoss J Samuvel

Title
InstitutionMedical University of South Carolina
DepartmentBiochemistry & Molecular Biology
AddressP.O. Box MSC 752
Phone843-876-5133
Fax843-876-5152
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Samuvel DJ, Nguyen NT, Jaeschke H, Lemasters JJ, Wang X, Choo YM, Hamann MT, Zhong Z, Samuvel DJ, Nguyen NT, Jaeschke H, Lemasters JJ, Wang X, Choo YM, Hamann MT, Zhong Z. Platanosides, a Potential Botanical Drug Combination, Decrease Liver Injury Caused by Acetaminophen Overdose in Mice. J Nat Prod. 2022 07 22; 85(7):1779-1788. PMID: 35815804.
      Citations:    Fields:    Translation:Animals
    2. Samuvel DJ, Li L, Krishnasamy Y, Gooz M, Takemoto K, Woster PM, Lemasters JJ, Zhong Z, Samuvel DJ, Li L, Krishnasamy Y, Gooz M, Takemoto K, Woster PM, Lemasters JJ, Zhong Z. Mitochondrial depolarization after acute ethanol treatment drives mitophagy in living mice. Autophagy. 2022 11; 18(11):2671-2685. PMID: 35293288; PMCID: PMC9629059.
      Citations:    
    3. Happe M, Samuvel DJ, Ohtola JA, Korte JE, Westerink MAJ, Happe M, Samuvel DJ, Ohtola JA, Korte JE, Westerink MAJ. Race-related differences in functional antibody response to pneumococcal vaccination in HIV-infected individuals. Vaccine. 2019 03 14; 37(12):1622-1629. PMID: 30797636; PMCID: PMC6428581.
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    4. Carey HA, Hildreth BE, Samuvel DJ, Thies KA, Rosol TJ, Toribio RE, Charles JF, Ostrowski MC, Sharma SM, Carey HA, Hildreth BE, Samuvel DJ, Thies KA, Rosol TJ, Toribio RE, Charles JF, Ostrowski MC, Sharma SM. Eomes partners with PU.1 and MITF to Regulate Transcription Factors Critical for osteoclast differentiation. iScience. 2019 Jan 25; 11:238-245. PMID: 30634169; PMCID: PMC6327072.
      Citations:    
    5. Singh I, Samuvel DJ, Choi S, Saxena N, Singh AK, Won J, Singh I, Samuvel DJ, Choi S, Saxena N, Singh AK, Won J. Combination therapy of lovastatin and AMP-activated protein kinase activator improves mitochondrial and peroxisomal functions and clinical disease in experimental autoimmune encephalomyelitis model. Immunology. 2018 07; 154(3):434-451. PMID: 29331024; PMCID: PMC6002225.
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    6. Sundaramurthy S, Annamalai B, Samuvel DJ, Shippenberg TS, Jayanthi LD, Ramamoorthy S, Sundaramurthy S, Annamalai B, Samuvel DJ, Shippenberg TS, Jayanthi LD, Ramamoorthy S. Modulation of serotonin transporter function by kappa-opioid receptor ligands. Neuropharmacology. 2017 02; 113(Pt A):281-292. PMID: 27743931; PMCID: PMC5148672.
      Citations:    
    7. Samuvel DJ, Shunmugavel A, Singh AK, Singh I, Khan M, Samuvel DJ, Shunmugavel A, Singh AK, Singh I, Khan M. S-Nitrosoglutathione ameliorates acute renal dysfunction in a rat model of lipopolysaccharide-induced sepsis. J Pharm Pharmacol. 2016 Oct; 68(10):1310-9. PMID: 27484743; PMCID: PMC5028274.
      Citations:    
    8. Samuvel DJ, Saxena N, Dhindsa JS, Singh AK, Gill GS, Grobelny DW, Singh I, Samuvel DJ, Saxena N, Dhindsa JS, Singh AK, Gill GS, Grobelny DW, Singh I. AKP-11 - A Novel S1P1 Agonist with Favorable Safety Profile Attenuates Experimental Autoimmune Encephalomyelitis in Rat Model of Multiple Sclerosis. PLoS One. 2015; 10(10):e0141781. PMID: 26513477; PMCID: PMC4626178.
      Citations:    
    9. Lang H, Xing Y, Brown LN, Samuvel DJ, Panganiban CH, Havens LT, Balasubramanian S, Wegner M, Krug EL, Barth JL, Lang H, Xing Y, Brown LN, Samuvel DJ, Panganiban CH, Havens LT, Balasubramanian S, Wegner M, Krug EL, Barth JL. Neural stem/progenitor cell properties of glial cells in the adult mouse auditory nerve. Sci Rep. 2015 Aug 26; 5:13383. PMID: 26307538; PMCID: PMC4549618.
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    10. Lu Z, Li Y, Samuvel DJ, Jin J, Zhang X, Lopes-Virella MF, Huang Y, Lu Z, Li Y, Samuvel DJ, Jin J, Zhang X, Lopes-Virella MF, Huang Y. MD-2 is involved in the stimulation of matrix metalloproteinase-1 expression by interferon-? and high glucose in mononuclear cells?-?a potential role of MD-2 in Toll-like receptor 4-independent signalling. Immunology. 2013 Nov; 140(3):301-13. PMID: 23800176; PMCID: PMC3800435.
      Citations:    
    11. Xing Y, Samuvel DJ, Stevens SM, Dubno JR, Schulte BA, Lang H, Xing Y, Samuvel DJ, Stevens SM, Dubno JR, Schulte BA, Lang H. Age-related changes of myelin basic protein in mouse and human auditory nerve. PLoS One. 2012; 7(4):e34500. PMID: 22496821; PMCID: PMC3320625.
      Citations:    
    12. Jin J, Sundararaj KP, Samuvel DJ, Zhang X, Li Y, Lu Z, Lopes-Virella MF, Huang Y, Jin J, Sundararaj KP, Samuvel DJ, Zhang X, Li Y, Lu Z, Lopes-Virella MF, Huang Y. Different signaling mechanisms regulating IL-6 expression by LPS between gingival fibroblasts and mononuclear cells: seeking the common target. Clin Immunol. 2012 May; 143(2):188-99. PMID: 22386866; PMCID: PMC3343695.
      Citations:    
    13. Jin J, Samuvel DJ, Zhang X, Li Y, Lu Z, Lopes-Virella MF, Huang Y, Jin J, Samuvel DJ, Zhang X, Li Y, Lu Z, Lopes-Virella MF, Huang Y. Coactivation of TLR4 and TLR2/6 coordinates an additive augmentation on IL-6 gene transcription via p38MAPK pathway in U937 mononuclear cells. Mol Immunol. 2011 Dec; 49(3):423-32. PMID: 22030478; PMCID: PMC3224151.
      Citations:    
    14. Samuvel DJ, Jin J, Sundararaj KP, Li Y, Zhang X, Lopes-Virella MF, Huang Y, Samuvel DJ, Jin J, Sundararaj KP, Li Y, Zhang X, Lopes-Virella MF, Huang Y. TLR4 activation and IL-6-mediated cross talk between adipocytes and mononuclear cells synergistically stimulate MMP-1 expression. Endocrinology. 2011 Dec; 152(12):4662-71. PMID: 21952248; PMCID: PMC3230059.
      Citations:    
    15. Lang H, Li M, Kilpatrick LA, Zhu J, Samuvel DJ, Krug EL, Goddard JC, Lang H, Li M, Kilpatrick LA, Zhu J, Samuvel DJ, Krug EL, Goddard JC. Sox2 up-regulation and glial cell proliferation following degeneration of spiral ganglion neurons in the adult mouse inner ear. J Assoc Res Otolaryngol. 2011 Apr; 12(2):151-71. PMID: 21061038; PMCID: PMC3046328.
      Citations:    
    16. Li Y, Samuvel DJ, Sundararaj KP, Lopes-Virella MF, Huang Y, Li Y, Samuvel DJ, Sundararaj KP, Lopes-Virella MF, Huang Y. IL-6 and high glucose synergistically upregulate MMP-1 expression by U937 mononuclear phagocytes via ERK1/2 and JNK pathways and c-Jun. J Cell Biochem. 2010 May; 110(1):248-59. PMID: 20225236; PMCID: PMC2858773.
      Citations:    
    17. Ramamoorthy S, Samuvel DJ, Balasubramaniam A, See RE, Jayanthi LD, Ramamoorthy S, Samuvel DJ, Balasubramaniam A, See RE, Jayanthi LD. Altered dopamine transporter function and phosphorylation following chronic cocaine self-administration and extinction in rats. Biochem Biophys Res Commun. 2010 Jan 15; 391(3):1517-21. PMID: 20035724; PMCID: PMC2812585.
      Citations:    
    18. Samuvel DJ, Sundararaj KP, Li Y, Lopes-Virella MF, Huang Y, Samuvel DJ, Sundararaj KP, Li Y, Lopes-Virella MF, Huang Y. Adipocyte-mononuclear cell interaction, Toll-like receptor 4 activation, and high glucose synergistically up-regulate osteopontin expression via an interleukin 6-mediated mechanism. J Biol Chem. 2010 Feb 05; 285(6):3916-3927. PMID: 20007708; PMCID: PMC2823534.
      Citations:    
    19. Sundararaj KP, Samuvel DJ, Li Y, Sanders JJ, Lopes-Virella MF, Huang Y, Sundararaj KP, Samuvel DJ, Li Y, Sanders JJ, Lopes-Virella MF, Huang Y. Interleukin-6 released from fibroblasts is essential for up-regulation of matrix metalloproteinase-1 expression by U937 macrophages in coculture: cross-talking between fibroblasts and U937 macrophages exposed to high glucose. J Biol Chem. 2009 May 15; 284(20):13714-13724. PMID: 19307187; PMCID: PMC2679473.
      Citations:    
    20. Samuvel DJ, Sundararaj KP, Nareika A, Lopes-Virella MF, Huang Y, Samuvel DJ, Sundararaj KP, Nareika A, Lopes-Virella MF, Huang Y. Lactate boosts TLR4 signaling and NF-kappaB pathway-mediated gene transcription in macrophages via monocarboxylate transporters and MD-2 up-regulation. J Immunol. 2009 Feb 15; 182(4):2476-84. PMID: 19201903; PMCID: PMC2673542.
      Citations:    
    21. Sundararaj KP, Samuvel DJ, Li Y, Nareika A, Slate EH, Sanders JJ, Lopes-Virella MF, Huang Y, Sundararaj KP, Samuvel DJ, Li Y, Nareika A, Slate EH, Sanders JJ, Lopes-Virella MF, Huang Y. Simvastatin suppresses LPS-induced MMP-1 expression in U937 mononuclear cells by inhibiting protein isoprenylation-mediated ERK activation. J Leukoc Biol. 2008 Oct; 84(4):1120-9. PMID: 18625914; PMCID: PMC2538599.
      Citations:    
    22. Samuvel DJ, Jayanthi LD, Manohar S, Kaliyaperumal K, See RE, Ramamoorthy S, Samuvel DJ, Jayanthi LD, Manohar S, Kaliyaperumal K, See RE, Ramamoorthy S. Dysregulation of dopamine transporter trafficking and function after abstinence from cocaine self-administration in rats: evidence for differential regulation in caudate putamen and nucleus accumbens. J Pharmacol Exp Ther. 2008 Apr; 325(1):293-301. PMID: 18198344.
      Citations:    
    23. Zapata A, Kivell B, Han Y, Javitch JA, Bolan EA, Kuraguntla D, Jaligam V, Oz M, Jayanthi LD, Samuvel DJ, Ramamoorthy S, Shippenberg TS, Zapata A, Kivell B, Han Y, Javitch JA, Bolan EA, Kuraguntla D, Jaligam V, Oz M, Jayanthi LD, Samuvel DJ, Ramamoorthy S, Shippenberg TS. Regulation of dopamine transporter function and cell surface expression by D3 dopamine receptors. J Biol Chem. 2007 Dec 07; 282(49):35842-54. PMID: 17923483.
      Citations:    
    24. Adkins EM, Samuvel DJ, Fog JU, Eriksen J, Jayanthi LD, Vaegter CB, Ramamoorthy S, Gether U, Adkins EM, Samuvel DJ, Fog JU, Eriksen J, Jayanthi LD, Vaegter CB, Ramamoorthy S, Gether U. Membrane mobility and microdomain association of the dopamine transporter studied with fluorescence correlation spectroscopy and fluorescence recovery after photobleaching. Biochemistry. 2007 Sep 18; 46(37):10484-97. PMID: 17711354.
      Citations:    
    25. Ramamoorthy S, Samuvel DJ, Buck ER, Rudnick G, Jayanthi LD, Ramamoorthy S, Samuvel DJ, Buck ER, Rudnick G, Jayanthi LD. Phosphorylation of threonine residue 276 is required for acute regulation of serotonin transporter by cyclic GMP. J Biol Chem. 2007 Apr 20; 282(16):11639-47. PMID: 17310063.
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    26. Jayanthi LD, Annamalai B, Samuvel DJ, Gether U, Ramamoorthy S, Jayanthi LD, Annamalai B, Samuvel DJ, Gether U, Ramamoorthy S. Phosphorylation of the norepinephrine transporter at threonine 258 and serine 259 is linked to protein kinase C-mediated transporter internalization. J Biol Chem. 2006 Aug 18; 281(33):23326-40. PMID: 16740633.
      Citations:    
    27. Prasad HC, Zhu CB, McCauley JL, Samuvel DJ, Ramamoorthy S, Shelton RC, Hewlett WA, Sutcliffe JS, Blakely RD, Prasad HC, Zhu CB, McCauley JL, Samuvel DJ, Ramamoorthy S, Shelton RC, Hewlett WA, Sutcliffe JS, Blakely RD. Human serotonin transporter variants display altered sensitivity to protein kinase G and p38 mitogen-activated protein kinase. Proc Natl Acad Sci U S A. 2005 Aug 09; 102(32):11545-50. PMID: 16055563; PMCID: PMC1183547.
      Citations:    
    28. Jayanthi LD, Samuvel DJ, Blakely RD, Ramamoorthy S, Jayanthi LD, Samuvel DJ, Blakely RD, Ramamoorthy S. Evidence for biphasic effects of protein kinase C on serotonin transporter function, endocytosis, and phosphorylation. Mol Pharmacol. 2005 Jun; 67(6):2077-87. PMID: 15774771.
      Citations:    
    29. Samuvel DJ, Jayanthi LD, Bhat NR, Ramamoorthy S, Samuvel DJ, Jayanthi LD, Bhat NR, Ramamoorthy S. A role for p38 mitogen-activated protein kinase in the regulation of the serotonin transporter: evidence for distinct cellular mechanisms involved in transporter surface expression. J Neurosci. 2005 Jan 05; 25(1):29-41. PMID: 15634764; PMCID: PMC6725216.
      Citations:    
    30. Parameswaran N, Samuvel DJ, Kumar R, Thatai S, Bal V, Rath S, George A, Parameswaran N, Samuvel DJ, Kumar R, Thatai S, Bal V, Rath S, George A. Oral tolerance in T cells is accompanied by induction of effector function in lymphoid organs after systemic immunization. Infect Immun. 2004 Jul; 72(7):3803-11. PMID: 15213121; PMCID: PMC427424.
      Citations:    
    31. Jayanthi LD, Samuvel DJ, Ramamoorthy S, Jayanthi LD, Samuvel DJ, Ramamoorthy S. Regulated internalization and phosphorylation of the native norepinephrine transporter in response to phorbol esters. Evidence for localization in lipid rafts and lipid raft-mediated internalization. J Biol Chem. 2004 Apr 30; 279(18):19315-26. PMID: 14976208.
      Citations: 60     Fields:    Translation:AnimalsCells
    32. Xi ZX, Ramamoorthy S, Shen H, Lake R, Samuvel DJ, Kalivas PW, Xi ZX, Ramamoorthy S, Shen H, Lake R, Samuvel DJ, Kalivas PW. GABA transmission in the nucleus accumbens is altered after withdrawal from repeated cocaine. J Neurosci. 2003 Apr 15; 23(8):3498-505. PMID: 12716959; PMCID: PMC6742318.
      Citations: 47     Fields:    Translation:AnimalsCells
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