Johnell O Brooks

TitleAssociate Professor
InstitutionClemson University
DepartmentDepartment of Automotive Engineering
Address4 Research Drive
Greenville, South Carolina 29607
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    1. Brooks JO, Kruse JL, Kubicki A, Hellemann G, Espinoza RT, Irwin MR, Narr KL. Structural brain plasticity and inflammation are independently related to changes in depressive symptoms six months after an index ECT course. Psychol Med. 2023 Jan 05; 1-9. PMID: 36600668.
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    2. Thiruvalluru RK, Edgcomb JB, Brooks JO, Pathak J. Risk of suicide attempts and self-harm after 1.4 million general medical hospitalizations of men with mental illness. J Psychiatr Res. 2023 01; 157:50-56. PMID: 36436428.
      Citations:    Fields:    Translation:Humans
    3. Kruse JL, Olmstead R, Hellemann G, Breen EC, Tye SJ, Brooks JO, Wade B, Congdon E, Espinoza R, Narr KL, Irwin MR, Kruse JL, Olmstead R, Hellemann G, Breen EC, Tye SJ, Brooks JO, Wade B, Congdon E, Espinoza R, Narr KL, Irwin MR. Interleukin-8 and lower severity of depression in females, but not males, with treatment-resistant depression. J Psychiatr Res. 2021 08; 140:350-356. PMID: 34139457; PMCID: PMC8319139.
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    4. Edgcomb JB, Thiruvalluru R, Pathak J, Brooks JO, Edgcomb JB, Thiruvalluru R, Pathak J, Brooks JO. Machine Learning to Differentiate Risk of Suicide Attempt and Self-harm After General Medical Hospitalization of Women With Mental Illness. Med Care. 2021 02 01; 59:S58-S64. PMID: 33438884; PMCID: PMC7810157.
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    5. Edgcomb JB, Shaddox T, Hellemann G, Brooks JO, Edgcomb JB, Shaddox T, Hellemann G, Brooks JO. Predicting suicidal behavior and self-harm after general hospitalization of adults with serious mental illness. J Psychiatr Res. 2021 04; 136:515-521. PMID: 33218748; PMCID: PMC8009812.
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    6. Njau S, Townsend J, Wade B, Hellemann G, Bookheimer S, Narr K, Brooks JO, Njau S, Townsend J, Wade B, Hellemann G, Bookheimer S, Narr K, Brooks JO. Neural Subtypes of Euthymic Bipolar I Disorder Characterized by Emotion Regulation Circuitry. Biol Psychiatry Cogn Neurosci Neuroimaging. 2020 06; 5(6):591-600. PMID: 32513391.
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    7. Edgcomb J, Shaddox T, Hellemann G, Brooks JO, Edgcomb J, Shaddox T, Hellemann G, Brooks JO. High-Risk Phenotypes of Early Psychiatric Readmission in Bipolar Disorder With Comorbid?Medical Illness. Psychosomatics. 2019 Nov - Dec; 60(6):563-573. PMID: 31279490; PMCID: PMC7071814.
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    8. Lucas JA, Moore JB, Davis S, Brooks JO, Miles C, Lucas JA, Moore JB, Davis S, Brooks JO, Miles C. Provider attitudes and management regarding returning to drive after concussion. Br J Sports Med. 2019 Apr; 53(8):495. PMID: 29530943; PMCID: PMC6579502.
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    9. Brooks J, Seeanner J, Hennessy S, Manganelli J, Crisler M, Rosopa P, Jenkins C, Anderson M, Drouin N, Belle L, Truesdail C, Tanner S, Brooks J, Seeanner J, Hennessy S, Manganelli J, Crisler M, Rosopa P, Jenkins C, Anderson M, Drouin N, Belle L, Truesdail C, Tanner S. Interactive Tools for Measuring Visual Scanning Performance and Reaction Time. Am J Occup Ther. 2017 Mar/Apr; 71(2):7102350010p1-20102350020p6. PMID: 28218598; PMCID: PMC5317392.
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    10. Threatt AL, Merino J, Brooks JO, Healy S, Truesdail C, Manganelli J, Walker I, Green KE, Threatt AL, Merino J, Brooks JO, Healy S, Truesdail C, Manganelli J, Walker I, Green KE. The Design, Prototyping, and Formative Evaluation of an Assistive Robotic Table (ART) for Stroke Patients. HERD. 2017 Apr; 10(3):152-169. PMID: 28335630.
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    11. Jackson LT, Crisler MC, Tanner SL, Brooks JO, Jeray KJ, Jackson LT, Crisler MC, Tanner SL, Brooks JO, Jeray KJ. Effects of Upper Extremity Immobilization and Use of a Spinner Knob on Vehicle Steering. Hand (N Y). 2017 11; 12(6):597-605. PMID: 29091484; PMCID: PMC5669326.
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    12. Brooks J, Kellett J, Seeanner J, Jenkins C, Buchanan C, Kinsman A, Kelly D, Pierce S, Brooks J, Kellett J, Seeanner J, Jenkins C, Buchanan C, Kinsman A, Kelly D, Pierce S. Training the Motor Aspects of Pre-driving Skills of Young Adults With and Without Autism Spectrum Disorder. J Autism Dev Disord. 2016 Jul; 46(7):2408-26. PMID: 27055416.
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    13. Jain FA, Hunter AM, Leuchter AF, Brooks JO, Jain FA, Hunter AM, Leuchter AF, Brooks JO. A role for profiles of patient-specific depression characteristics and socioeconomic factors in the prediction of antidepressant treatment outcome. J Clin Psychiatry. 2015 Mar; 76(3):327. PMID: 25830451.
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    14. Healy S, Manganelli J, Rosopa PJ, Brooks JO, Healy S, Manganelli J, Rosopa PJ, Brooks JO. An Exploration of the Nightstand and Over-the-Bed Table in an Inpatient Rehabilitation Hospital. HERD. 2015; 8(2):43-55. PMID: 25816380.
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    15. Xi Y, Rosopa PJ, Mossey M, Crisler MC, Drouin N, Kopera K, Brooks JO, Xi Y, Rosopa PJ, Mossey M, Crisler MC, Drouin N, Kopera K, Brooks JO. The reliability of a VISION COACH task as a measure of psychomotor skills. Occup Ther Health Care. 2014 Oct; 28(4):444-54. PMID: 25181563.
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    16. Lowe E, Drouin N, Venhovens PJ, Brooks JO, Lowe E, Drouin N, Venhovens PJ, Brooks JO. Understanding the needs of hand control users, driver rehabilitation specialists, and dealers/installers. Occup Ther Health Care. 2014 Oct; 28(4):394-409. PMID: 25050985.
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    17. Brooks JO, Vizueta N, Brooks JO, Vizueta N. Diagnostic and clinical implications of functional neuroimaging in bipolar disorder. J Psychiatr Res. 2014 Oct; 57:12-25. PMID: 25015683.
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    18. Kruse JL, Jeffrey JK, Davis MC, Dearlove J, IsHak WW, Brooks JO, Kruse JL, Jeffrey JK, Davis MC, Dearlove J, IsHak WW, Brooks JO. Anti-N-methyl-D-aspartate receptor encephalitis: a targeted review of clinical presentation, diagnosis, and approaches to psychopharmacologic management. Ann Clin Psychiatry. 2014 May; 26(2):111-9. PMID: 24501734.
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    19. Mossey ME, Xi Y, McConomy SK, Brooks JO, Rosopa PJ, Venhovens PJ, Mossey ME, Xi Y, McConomy SK, Brooks JO, Rosopa PJ, Venhovens PJ. Evaluation of four steering wheels to determine driver hand placement in a static environment. Appl Ergon. 2014 Jul; 45(4):1187-95. PMID: 24674782.
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    20. Manganelli J, Threatt A, Brooks JO, Healy S, Merino J, Yanik P, Walker I, Green K, Manganelli J, Threatt A, Brooks JO, Healy S, Merino J, Yanik P, Walker I, Green K. Confirming, Classifying, and Prioritizing Needed Over-the-Bed Table Improvements via Methodological Triangulation. HERD. 2014; 8(1):94-114. PMID: 25816185.
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    21. Manganelli J, Threatt A, Brooks JO, Healy S, Merino J, Yanik P, Walker I, Green K, Manganelli J, Threatt A, Brooks JO, Healy S, Merino J, Yanik P, Walker I, Green K. Examination of How and Why Over-the-Bed Tables Are Used: Use Cases and Needs from Healthcare Providers. HERD. 2014; 7(2):104-26. PMID: 24554359.
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    22. Friedman L, Brooks JO, Bliwise DL, Yesavage JA, Friedman L, Brooks JO, Bliwise DL, Yesavage JA. Insomnia in Older Adults: Relations to Depression and Anxiety. Am J Geriatr Psychiatry. 1993 Spring; 1(2):153-159. PMID: 28531030.
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    23. Jain FA, Hunter AM, Brooks JO, Leuchter AF, Jain FA, Hunter AM, Brooks JO, Leuchter AF. Predictive socioeconomic and clinical profiles of antidepressant response and remission. Depress Anxiety. 2013 Jul; 30(7):624-30. PMID: 23288666.
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    24. Manganelli J, Threatt A, Brooks JO, Smolentzov L, Mossey M, Healy S, Walker I, Green K, Manganelli J, Threatt A, Brooks JO, Smolentzov L, Mossey M, Healy S, Walker I, Green K. Examination of overbed tables: healthcare provider and user preferences. HERD. 2013; 6(3):9-29. PMID: 23817904.
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    25. Goodenough RR, Brooks JO, Crisler MC, Rosopa PJ, Goodenough RR, Brooks JO, Crisler MC, Rosopa PJ. Developing a driving simulator based functional object detection task. Occup Ther Health Care. 2012 Oct; 26(4):240-56. PMID: 23899199.
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    26. Maldonado JR, Nguyen LH, Schader EM, Brooks JO, Maldonado JR, Nguyen LH, Schader EM, Brooks JO. Benzodiazepine loading versus symptom-triggered treatment of alcohol withdrawal: a prospective, randomized clinical trial. Gen Hosp Psychiatry. 2012 Nov-Dec; 34(6):611-7. PMID: 22898443.
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    27. Foland-Ross LC, Brooks JO, Mintz J, Bartzokis G, Townsend J, Thompson PM, Altshuler LL, Foland-Ross LC, Brooks JO, Mintz J, Bartzokis G, Townsend J, Thompson PM, Altshuler LL. Mood-state effects on amygdala volume in bipolar disorder. J Affect Disord. 2012 Aug; 139(3):298-301. PMID: 22521854; PMCID: PMC3372678.
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    28. Balk SA, Brooks JO, Klein N, Grygier J, Balk SA, Brooks JO, Klein N, Grygier J. Pedestrians' estimates of their own visibility: a simple and effective computer-based technique. J Safety Res. 2012 Apr; 43(2):101-6. PMID: 22709994.
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    29. Ittasakul P, Johnson KR, Srivastava S, Childers ME, Brooks JO, Hoblyn JC, Ketter TA, Ittasakul P, Johnson KR, Srivastava S, Childers ME, Brooks JO, Hoblyn JC, Ketter TA. Effectiveness of quetiapine plus lamotrigine maintenance therapy in challenging bipolar disorder patients. J Affect Disord. 2012 Mar; 137(1-3):139-45. PMID: 22240084.
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    30. Crisler MC, Brooks JO, Venhovens PJ, Healy SL, Hirth VA, McKee JA, Duckworth K, Crisler MC, Brooks JO, Venhovens PJ, Healy SL, Hirth VA, McKee JA, Duckworth K. Seniors' and physicians' attitudes toward using driving simulators in clinical settings. Occup Ther Health Care. 2012 Jan; 26(1):1-15. PMID: 23899104.
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    31. Yuen HK, Brooks JO, Azuero A, Burik JK, Yuen HK, Brooks JO, Azuero A, Burik JK. Certified driver rehabilitation specialists' preferred situations for driving simulator scenarios. Am J Occup Ther. 2012 Jan-Feb; 66(1):110-4. PMID: 22389946.
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    32. Brooks JO, Smolentzov L, Mossey ME, Carroll C, Kendrick K, Sprogis K, Manganelli J, Healy SL, Kopera K, Walker I, Green K, Brooks JO, Smolentzov L, Mossey ME, Carroll C, Kendrick K, Sprogis K, Manganelli J, Healy SL, Kopera K, Walker I, Green K. Group differences in preferences for a novel nightstand. HERD. 2012; 5(4):88-97. PMID: 23224809.
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    33. Brooks JO, Dickerson A, Crisler MC, Logan WC, Beeco RW, Witte JC, Brooks JO, Dickerson A, Crisler MC, Logan WC, Beeco RW, Witte JC. Physician knowledge, assessment, and reporting of older driver fitness. Occup Ther Health Care. 2011 Oct; 25(4):213-24. PMID: 23899076.
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    34. Jain FA, Brooks JO, Larsen KA, Kelly SE, Bode RH, Sweeney GA, Stern TA, Jain FA, Brooks JO, Larsen KA, Kelly SE, Bode RH, Sweeney GA, Stern TA. Individual risk profiles for postoperative delirium after joint replacement surgery. Psychosomatics. 2011 Sep-Oct; 52(5):410-6. PMID: 21907058.
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    35. Brooks JO, Foland-Ross LC, Thompson PM, Altshuler LL, Brooks JO, Foland-Ross LC, Thompson PM, Altshuler LL. Preliminary evidence of within-subject changes in gray matter density associated with remission of bipolar depression. Psychiatry Res. 2011 Jul 30; 193(1):53-5. PMID: 21561743; PMCID: PMC3986411.
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    36. Orr RK, Hoehn JL, Col NF, Brooks JO, Smolentzov L, Dearment A, Logan W, Green K, Walker I, Honchar J, Guirl C, Beeco R, Blakeney C, Boggs A, Carroll C, Duckworth K, Goller L, Ham S, Healy S, Heaps C, Hayden C, Manganelli J, Mayweather L, Mixon H, Price K, Reis A, Yanik P. Toward a "smart" nightstand prototype: an examination of nightstand table contents and preferences. HERD. 2011; 4(2):91-108. PMID: 21465437.
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    37. Brooks JO, Crisler MC, Klein N, Goodenough R, Beeco RW, Guirl C, Tyler PJ, Hilpert A, Miller Y, Grygier J, Burroughs B, Martin A, Ray R, Palmer C, Beck C, Brooks JO, Crisler MC, Klein N, Goodenough R, Beeco RW, Guirl C, Tyler PJ, Hilpert A, Miller Y, Grygier J, Burroughs B, Martin A, Ray R, Palmer C, Beck C. Speed choice and driving performance in simulated foggy conditions. Accid Anal Prev. 2011 May; 43(3):698-705. PMID: 21376857.
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    38. Brooks JO, Bearden CE, Hoblyn JC, Woodard SA, Ketter TA, Brooks JO, Bearden CE, Hoblyn JC, Woodard SA, Ketter TA. Prefrontal and paralimbic metabolic dysregulation related to sustained attention in euthymic older adults with bipolar disorder. Bipolar Disord. 2010 Dec; 12(8):866-74. PMID: 21176034.
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    39. Brooks JO, Goldberg JF, Ketter TA, Miklowitz DJ, Calabrese JR, Bowden CL, Thase ME, Brooks JO, Goldberg JF, Ketter TA, Miklowitz DJ, Calabrese JR, Bowden CL, Thase ME. Safety and tolerability associated with second-generation antipsychotic polytherapy in bipolar disorder: findings from the Systematic Treatment Enhancement Program for Bipolar Disorder. J Clin Psychiatry. 2011 Feb; 72(2):240-7. PMID: 20868629.
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    40. Brooks JO, Goodenough RR, Crisler MC, Klein ND, Alley RL, Koon BL, Logan WC, Ogle JH, Tyrrell RA, Wills RF, Brooks JO, Goodenough RR, Crisler MC, Klein ND, Alley RL, Koon BL, Logan WC, Ogle JH, Tyrrell RA, Wills RF. Simulator sickness during driving simulation studies. Accid Anal Prev. 2010 May; 42(3):788-96. PMID: 20380904.
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    41. Ketter TA, Brooks JO, Hoblyn JC, Holland AA, Nam JY, Culver JL, Marsh WK, Bonner JC, Ketter TA, Brooks JO, Hoblyn JC, Holland AA, Nam JY, Culver JL, Marsh WK, Bonner JC. Long-term effectiveness of quetiapine in bipolar disorder in a clinical setting. J Psychiatr Res. 2010 Oct; 44(14):921-9. PMID: 20378127.
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    42. Brooks JO, Hoblyn JC, Ketter TA, Brooks JO, Hoblyn JC, Ketter TA. Metabolic evidence of corticolimbic dysregulation in bipolar mania. Psychiatry Res. 2010 Feb 28; 181(2):136-40. PMID: 20080037.
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    43. Brooks JO, Rosen AC, Hoblyn JC, Woodard SA, Krasnykh O, Ketter TA, Brooks JO, Rosen AC, Hoblyn JC, Woodard SA, Krasnykh O, Ketter TA. Resting prefrontal hypometabolism and paralimbic hypermetabolism related to verbal recall deficits in euthymic older adults with bipolar disorder. Am J Geriatr Psychiatry. 2009 Dec; 17(12):1022-9. PMID: 20104059.
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    44. Orr RK, Hoehn JL, Col NF, Brooks JO, Bonner JC, Rosen AC, Wang PW, Hoblyn JC, Hill SJ, Ketter TA. Dorsolateral and dorsomedial prefrontal gray matter density changes associated with bipolar depression. Psychiatry Res. 2009 Jun 30; 172(3):200-4. PMID: 19351579; PMCID: PMC3265395.
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    45. Goldberg JF, Brooks JO, Kurita K, Hoblyn JC, Ghaemi SN, Perlis RH, Miklowitz DJ, Ketter TA, Sachs GS, Thase ME, Goldberg JF, Brooks JO, Kurita K, Hoblyn JC, Ghaemi SN, Perlis RH, Miklowitz DJ, Ketter TA, Sachs GS, Thase ME. Depressive illness burden associated with complex polypharmacy in patients with bipolar disorder: findings from the STEP-BD. J Clin Psychiatry. 2009 Feb; 70(2):155-62. PMID: 19210946; PMCID: PMC10034852.
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    46. Brooks JO, Chang HS, Krasnykh O, Brooks JO, Chang HS, Krasnykh O. Metabolic risks in older adults receiving second-generation antipsychotic medication. Curr Psychiatry Rep. 2009 Feb; 11(1):33-40. PMID: 19187706.
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    47. Hoblyn JC, Balt SL, Woodard SA, Brooks JO, Hoblyn JC, Balt SL, Woodard SA, Brooks JO. Substance use disorders as risk factors for psychiatric hospitalization in bipolar disorder. Psychiatr Serv. 2009 Jan; 60(1):50-5. PMID: 19114570.
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    48. Law CW, Soczynska JK, Woldeyohannes HO, Miranda A, Brooks JO, McIntyre RS, Law CW, Soczynska JK, Woldeyohannes HO, Miranda A, Brooks JO, McIntyre RS. Relation between cigarette smoking and cognitive function in euthymic individuals with bipolar disorder. Pharmacol Biochem Behav. 2009 Mar; 92(1):12-6. PMID: 18976682.
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    49. Brooks JO, Hoblyn JC, Woodard SA, Rosen AC, Ketter TA, Brooks JO, Hoblyn JC, Woodard SA, Rosen AC, Ketter TA. Corticolimbic metabolic dysregulation in euthymic older adults with bipolar disorder. J Psychiatr Res. 2009 Feb; 43(5):497-502. PMID: 18947837; PMCID: PMC2693401.
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    50. Gruber J, Harvey AG, Wang PW, Brooks JO, Thase ME, Sachs GS, Ketter TA, Gruber J, Harvey AG, Wang PW, Brooks JO, Thase ME, Sachs GS, Ketter TA. Sleep functioning in relation to mood, function, and quality of life at entry to the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD). J Affect Disord. 2009 Apr; 114(1-3):41-9. PMID: 18707765; PMCID: PMC2677624.
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    51. Brooks JO, Wang PW, Bonner JC, Rosen AC, Hoblyn JC, Hill SJ, Ketter TA, Brooks JO, Wang PW, Bonner JC, Rosen AC, Hoblyn JC, Hill SJ, Ketter TA. Decreased prefrontal, anterior cingulate, insula, and ventral striatal metabolism in medication-free depressed outpatients with bipolar disorder. J Psychiatr Res. 2009 Jan; 43(3):181-8. PMID: 18582900; PMCID: PMC3265392.
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    52. Yuen HK, Sharma AK, Logan WC, Gillespie MB, Day TA, Brooks JO, Yuen HK, Sharma AK, Logan WC, Gillespie MB, Day TA, Brooks JO. Radiation dose, driving performance, and cognitive function in patients with head and neck cancer. Radiother Oncol. 2008 May; 87(2):304-7. PMID: 18423670.
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    53. Balk SA, Tyrrell RA, Brooks JO, Carpenter TL, Balk SA, Tyrrell RA, Brooks JO, Carpenter TL. Highlighting human form and motion information enhances the conspicuity of pedestrians at night. Perception. 2008; 37(8):1276-84. PMID: 18853562.
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    54. O'Hara R, Brooks JO, Friedman L, Schröder CM, Morgan KS, Kraemer HC, O'Hara R, Brooks JO, Friedman L, Schr?der CM, Morgan KS, Kraemer HC. Long-term effects of mnemonic training in community-dwelling older adults. J Psychiatr Res. 2007 Oct; 41(7):585-90. PMID: 16780878.
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    55. Brooks JO, Hoblyn JC, Kraemer HC, Yesavage JA, Brooks JO, Hoblyn JC, Kraemer HC, Yesavage JA. Factors associated with psychiatric hospitalization of individuals diagnosed with dementia and comorbid bipolar disorder. J Geriatr Psychiatry Neurol. 2006 Jun; 19(2):72-7. PMID: 16690991.
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    56. Brooks JO, Wang PW, Strong C, Sachs N, Hoblyn JC, Fenn R, Ketter TA, Brooks JO, Wang PW, Strong C, Sachs N, Hoblyn JC, Fenn R, Ketter TA. Preliminary evidence of differential relations between prefrontal cortex metabolism and sustained attention in depressed adults with bipolar disorder and healthy controls. Bipolar Disord. 2006 Jun; 8(3):248-54. PMID: 16696826.
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    57. Brooks JO, Hoblyn JC, Brooks JO, Hoblyn JC. Secondary mania in older adults. Am J Psychiatry. 2005 Nov; 162(11):2033-8. PMID: 16263839.
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    58. Hoblyn J, Noda A, Yesavage JA, Brooks JO, Sheikh J, Lee T, Tinklenberg JR, Schneider B, O'Hara R, Leslie DL, Rosenheck RA, Kraemer HC, Hoblyn J, Noda A, Yesavage JA, Brooks JO, Sheikh J, Lee T, Tinklenberg JR, Schneider B, O'Hara R, Leslie DL, Rosenheck RA, Kraemer HC. Factors in choosing atypical antipsychotics: toward understanding the bases of physicians' prescribing decisions. J Psychiatr Res. 2006 Mar; 40(2):160-6. PMID: 16150458.
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    59. Brooks JO, Tyrrell RA, Frank TA, Brooks JO, Tyrrell RA, Frank TA. The effects of severe visual challenges on steering performance in visually healthy young drivers. Optom Vis Sci. 2005 Aug; 82(8):689-97. PMID: 16127334.
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    60. Hoblyn JC, Brooks JO, Hoblyn JC, Brooks JO. Herbal supplements in older adults. Consider interactions and adverse events that may result from supplement use. Geriatrics. 2005 Feb; 60(2):18, 22-3. PMID: 15742918.
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    61. Tyrrell RA, Patton CW, Brooks JO, Tyrrell RA, Patton CW, Brooks JO. Educational interventions successfully reduce pedestrians' overestimates of their own nighttime visibility. Hum Factors. 2004; 46(1):170-82. PMID: 15151163.
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    62. Brooks JO, Friedman L, Yesavage JA, Brooks JO, Friedman L, Yesavage JA. Use of an external mnemonic to augment the efficacy of an internal mnemonic in older adults. Int Psychogeriatr. 2003 Mar; 15(1):59-67. PMID: 12834200.
      Citations: 1     Fields:    Translation:Humans
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