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Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo.
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Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo.
Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo. Genes Dev. 2015 Aug 15; 29(16):1707-20.
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PubMed
subject areas
Animals
Carcinoma
Cell Nucleus
Cells, Cultured
Embryo, Mammalian
Enzyme Activation
Female
Gene Knock-In Techniques
Mice
Mutation, Missense
Oncogene Protein v-akt
Protein Stability
PTEN Phosphohydrolase
Signal Transduction
authors with profiles
Gustavo Leone
Maria Cuitino
Michael C Ostrowski
Christopher S Koivisto
Cynthia Timmers