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Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome.
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Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome.
Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome. Science. 2006 Apr 07; 312(5770):117-21.
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PubMed
subject areas
Adrenergic beta-Antagonists
Angiotensin II Type 1 Receptor Blockers
Animals
Antibodies
Aorta
Aortic Aneurysm
Disease Models, Animal
Elastic Tissue
Female
Fibrillin-1
Fibrillins
Losartan
Lung
Lung Diseases
Marfan Syndrome
Mice
Microfilament Proteins
Mutation
Neutralization Tests
Pregnancy
Pregnancy Complications
Propranolol
Pulmonary Alveoli
Receptor, Angiotensin, Type 1
Signal Transduction
Transforming Growth Factor beta
authors with profiles
Daniel P Judge