Adipocyte-mononuclear cell interaction, Toll-like receptor 4 activation, and high glucose synergistically up-regulate osteopontin expression via an interleukin 6-mediated mechanism.

Adipocyte-mononuclear cell interaction, Toll-like receptor 4 activation, and high glucose synergistically up-regulate osteopontin expression via an interleukin 6-mediated mechanism. J Biol Chem. 2010 Feb 05; 285(6):3916-3927.

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subject areas

Adipocytes
Antibodies
Cell Communication
Cells, Cultured
Coculture Techniques
Dose-Response Relationship, Drug
Electrophoretic Mobility Shift Assay
Enzyme-Linked Immunosorbent Assay
Flavonoids
Gene Expression
Glucose
Humans
Imidazoles
Interleukin-6
Leukocytes, Mononuclear
Lipopolysaccharides
Osteopontin
p38 Mitogen-Activated Protein Kinases
Pyridines
Recombinant Proteins
Reverse Transcriptase Polymerase Chain Reaction
RNA Interference
Signal Transduction
Toll-Like Receptor 4
Transcription Factor AP-1
U937 Cells

authors with profiles

Devadoss J Samuvel
Kamala Prabha Sundararaj
Maria F Lopes-Virella