SU5416 and EGCG work synergistically and inhibit angiogenic and survival factors and induce cell cycle arrest to promote apoptosis in human malignant neuroblastoma SH-SY5Y and SK-N-BE2 cells.

SU5416 and EGCG work synergistically and inhibit angiogenic and survival factors and induce cell cycle arrest to promote apoptosis in human malignant neuroblastoma SH-SY5Y and SK-N-BE2 cells. Neurochem Res. 2011 Aug; 36(8):1383-96.

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subject areas

Angiogenesis Inhibitors
Anticarcinogenic Agents
Apoptosis
Catechin
Cell Cycle
Cell Line, Tumor
Cell Movement
Cell Survival
Cyclin-Dependent Kinase 2
Cyclin-Dependent Kinase Inhibitor p21
E2F1 Transcription Factor
Humans
In Situ Nick-End Labeling
Indoles
Neovascularization, Pathologic
Neuroblastoma
Poly(ADP-ribose) Polymerases
Proto-Oncogene Proteins c-bcl-2
Pyrroles
Retinoblastoma Protein
Vascular Endothelial Growth Factor A
Vascular Endothelial Growth Factor Receptor-2

authors with profiles

Swapan KUMAR Ray