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Loss of integrin alpha(v)beta6-mediated TGF-beta activation causes Mmp12-dependent emphysema.
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Loss of integrin alpha(v)beta6-mediated TGF-beta activation causes Mmp12-dependent emphysema.
Loss of integrin alpha(v)beta6-mediated TGF-beta activation causes Mmp12-dependent emphysema. Nature. 2003 Mar 13; 422(6928):169-73.
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PubMed
subject areas
Aging
Animals
Antigens, Neoplasm
Disease Progression
Disease Susceptibility
Gene Deletion
Humans
Inflammation
Integrin beta Chains
Integrins
Macrophages, Alveolar
Matrix Metalloproteinase 12
Metalloendopeptidases
Mice
Mice, Knockout
Mice, Transgenic
Pulmonary Emphysema
Transforming Growth Factor beta
authors with profiles
Steven D. Shapiro