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Discovery of novel and potent aryl diamines as leukotriene A4 hydrolase inhibitors.
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Discovery of novel and potent aryl diamines as leukotriene A4 hydrolase inhibitors.
Discovery of novel and potent aryl diamines as leukotriene A4 hydrolase inhibitors. Bioorg Med Chem Lett. 2008 Jul 15; 18(14):3895-8.
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PubMed
subject areas
Administration, Oral
Animals
Anti-Inflammatory Agents
Biological Availability
Chemistry, Pharmaceutical
Diamines
Dogs
Drug Design
Enzyme Inhibitors
Epoxide Hydrolases
Humans
Inhibitory Concentration 50
Kinetics
Models, Chemical
Rats
authors with profiles
Thomas A. Kirkland