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Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt.
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Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt.
Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt. Mol Cell. 2016 06 16; 62(6):929-942.
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subject areas
Adaptor Proteins, Signal Transducing
Animals
Antineoplastic Combined Chemotherapy Protocols
Cell Proliferation
Cyclin D
Cyclin-Dependent Kinase 4
Cyclin-Dependent Kinase 6
Dose-Response Relationship, Drug
Drug Resistance, Neoplasm
Drug Synergism
Enzyme Activation
HCT116 Cells
HEK293 Cells
HeLa Cells
Humans
Mechanistic Target of Rapamycin Complex 2
Mice
Molecular Targeted Therapy
Multiprotein Complexes
Neoplasms
Phosphorylation
Protein Binding
Protein Interaction Domains and Motifs
Protein Kinase Inhibitors
Proto-Oncogene Proteins c-akt
Retinoblastoma Protein
RNA Interference
Signal Transduction
Time Factors
TOR Serine-Threonine Kinases
Transfection
authors with profiles
Wenjian Gan