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pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner.
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pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner.
pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner. Science. 2016 08 26; 353(6302):929-32.
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PubMed
subject areas
Cell Line, Tumor
Enzyme Activation
Humans
Hydroxylation
Hypoxia-Inducible Factor-Proline Dioxygenases
Mutation
Neoplasms
Phosphorylation
Proline
Proto-Oncogene Proteins c-akt
Tumor Hypoxia
Tumor Microenvironment
Von Hippel-Lindau Tumor Suppressor Protein
authors with profiles
Wenjian Gan