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    • TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling.
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TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling.

TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling. Nature. 2017 05 18; 545(7654):365-369.

View in: PubMed

subject areas
  • Adaptor Proteins, Signal Transducing
  • Animals
  • Carcinogenesis
  • Cell Line
  • Endopeptidases
  • Enzyme Activation
  • Female
  • Homeostasis
  • Humans
  • Lung Neoplasms
  • Mechanistic Target of Rapamycin Complex 1
  • Mechanistic Target of Rapamycin Complex 2
  • Mice
  • MTOR Associated Protein, LST8 Homolog
  • Multiprotein Complexes
  • Phosphorylation
  • Polyubiquitin
  • Protein Binding
  • Protein Subunits
  • Proto-Oncogene Proteins c-akt
  • Signal Transduction
  • TNF Receptor-Associated Factor 2
  • TOR Serine-Threonine Kinases
  • Ubiquitin
  • Ubiquitination

authors with profiles
  • Wenjian Gan