Myeloid-Derived Suppressor Cells Produce IL-10 to Elicit DNMT3b-Dependent IRF8 Silencing to Promote Colitis-Associated Colon Tumorigenesis.

Myeloid-Derived Suppressor Cells Produce IL-10 to Elicit DNMT3b-Dependent IRF8 Silencing to Promote Colitis-Associated Colon Tumorigenesis. Cell Rep. 2018 12 11; 25(11):3036-3046.e6.

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subject areas

Animals
Carcinogenesis
Colitis
Colonic Neoplasms
DNA (Cytosine-5-)-Methyltransferase 1
DNA (Cytosine-5-)-Methyltransferases
DNA Methylation
Epithelial Cells
Gene Expression Regulation, Neoplastic
Gene Silencing
Inflammation
Interferon Regulatory Factors
Interleukin-10
Mice, Inbred C57BL
Myeloid-Derived Suppressor Cells
Promoter Regions, Genetic
STAT3 Transcription Factor
Up-Regulation

authors with profiles

Phillip Joe Buckhaults