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Thrombin contributes to cancer immune evasion via proteolysis of platelet-bound GARP to activate LTGF-?.
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Thrombin contributes to cancer immune evasion via proteolysis of platelet-bound GARP to activate LTGF-?.
Thrombin contributes to cancer immune evasion via proteolysis of platelet-bound GARP to activate LTGF-?. Sci Transl Med. 2020 01 08; 12(525).
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PubMed
subject areas
Animals
Blood Platelets
Carcinogenesis
Cell Membrane
Disease Progression
Humans
Immune Evasion
Latent TGF-beta Binding Proteins
Membrane Proteins
Mice, Inbred BALB C
Mice, Inbred C57BL
Neoplasms
Protein Binding
Proteolysis
Thrombin
Tumor Microenvironment
authors with profiles
Bei Liu
Amy H. Wahlquist
Mark P Rubinstein
Shaoli Sun
Zihai Li
Michael B. Lilly
Carsten Krieg
Alessandra Metelli
Silvia Guglietta