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    • Synthesis and evaluation of novel inhibitors of Pim-1 and Pim-2 protein kinases.
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Synthesis and evaluation of novel inhibitors of Pim-1 and Pim-2 protein kinases.

Synthesis and evaluation of novel inhibitors of Pim-1 and Pim-2 protein kinases. J Med Chem. 2009 Jan 08; 52(1):74-86.

View in: PubMed

subject areas
  • Animals
  • Antineoplastic Agents
  • Cell Line
  • Cell-Free System
  • Combinatorial Chemistry Techniques
  • Female
  • Humans
  • Kinetics
  • Mice
  • Mice, Inbred BALB C
  • Models, Molecular
  • Molecular Structure
  • Neoplasm Transplantation
  • Neoplasms
  • Phosphorylation
  • Protein Kinase Inhibitors
  • Proto-Oncogene Proteins c-pim-1
  • Structure-Activity Relationship
  • Thiazolidinediones

authors with profiles
  • Wenxue Wang
  • Charles D. Smith
  • Andrew S Kraft
  • Campbell McInnes