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Lack of periostin leads to suppression of Notch1 signaling and calcific aortic valve disease.

Lack of periostin leads to suppression of Notch1 signaling and calcific aortic valve disease. Physiol Genomics. 2009 Nov 06; 39(3):160-8.

View in: PubMed

subject areas
  • Animals
  • Aortic Valve
  • Calcinosis
  • Calcium-Binding Proteins
  • Carrier Proteins
  • Cell Adhesion Molecules
  • Core Binding Factor Alpha 1 Subunit
  • Cytokines
  • Echocardiography
  • Embryo, Mammalian
  • Gene Expression Profiling
  • Gene Expression Regulation, Developmental
  • Heart Valve Diseases
  • In Situ Hybridization, Fluorescence
  • Intercellular Signaling Peptides and Proteins
  • Mice
  • Mice, Inbred C57BL
  • Mice, Knockout
  • Myocardium
  • Osteopontin
  • Receptor, Notch1
  • Reverse Transcriptase Polymerase Chain Reaction
  • Signal Transduction
  • Time Factors

authors with profiles
  • Ricardo A. Moreno
  • Roger R. Markwald