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    • p53-dependent induction of prostate cancer cell senescence by the PIM1 protein kinase.
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p53-dependent induction of prostate cancer cell senescence by the PIM1 protein kinase.

p53-dependent induction of prostate cancer cell senescence by the PIM1 protein kinase. Mol Cancer Res. 2010 Aug; 8(8):1126-41.

View in: PubMed

subject areas
  • Animals
  • Apoptosis
  • beta-Galactosidase
  • Blotting, Western
  • Cell Proliferation
  • Cells, Cultured
  • Cellular Senescence
  • Checkpoint Kinase 2
  • COS Cells
  • Cyclin-Dependent Kinase Inhibitor p21
  • Embryo, Mammalian
  • Fibroblasts
  • Genes, Dominant
  • Genomic Instability
  • Humans
  • Immunoenzyme Techniques
  • Interleukin-8
  • Male
  • Mice
  • Mice, Knockout
  • Mice, Nude
  • Phenotype
  • Polyploidy
  • Prostatic Neoplasms
  • Proto-Oncogene Proteins
  • Proto-Oncogene Proteins c-pim-1
  • Reverse Transcriptase Polymerase Chain Reaction
  • RNA, Messenger
  • RNA, Small Interfering
  • Transgenes
  • Tumor Suppressor Protein p53

authors with profiles
  • Michael B. Lilly
  • Andrew S Kraft