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A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death.
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A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death.
A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death. Nat Med. 2014 Dec; 20(12):1452-7.
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PubMed
subject areas
Aged
Aged, 80 and over
Alzheimer Disease
Amyloid beta-Peptides
Animals
CA3 Region, Hippocampal
Cell Death
Female
Genetic Predisposition to Disease
Glutamic Acid
HEK293 Cells
Humans
Male
Mice
Netrin Receptors
Neurons
Rats
Receptors, Cell Surface
Receptors, Nerve Growth Factor
Staurosporine
authors with profiles
Steven L. Carroll