Calcium signaling consequences of RyR2 mutations associated with CPVT1 introduced via CRISPR/Cas9 gene editing in human-induced pluripotent stem cell-derived cardiomyocytes: Comparison of RyR2-R420Q, F2483I, and Q4201R.

Calcium signaling consequences of RyR2 mutations associated with CPVT1 introduced via CRISPR/Cas9 gene editing in human-induced pluripotent stem cell-derived cardiomyocytes: Comparison of RyR2-R420Q, F2483I, and Q4201R. Heart Rhythm. 2021 02; 18(2):250-260.

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subject areas

Calcium
Calcium Signaling
Cell Differentiation
Clustered Regularly Interspaced Short Palindromic Repeats
DNA
DNA Mutational Analysis
Gene Editing
Humans
Induced Pluripotent Stem Cells
Mutation
Myocytes, Cardiac
Phenotype
Ryanodine Receptor Calcium Release Channel
Sarcoplasmic Reticulum
Tachycardia, Ventricular

authors with profiles

Martin Morad
Hua Wei