Specific Conformational Dynamics and Expansion Underpin a Multi-Step Mechanism for Specific Binding of p27 with Cdk2/Cyclin A.

Specific Conformational Dynamics and Expansion Underpin a Multi-Step Mechanism for Specific Binding of p27 with Cdk2/Cyclin A. J Mol Biol. 2020 04 17; 432(9):2998-3017.

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subject areas

Binding Sites
Cyclin A
Cyclin-Dependent Kinase 2
Cyclin-Dependent Kinase Inhibitor p27
Fluorescence Resonance Energy Transfer
Humans
Models, Molecular
Mutation
Protein Binding
Protein Conformation
Single Molecule Imaging
Spectrometry, Fluorescence
Ternary Complex Factors

authors with profiles

Hugo Sanabria