Plaque, Amyloid

"Plaque, Amyloid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Accumulations of extracellularly deposited AMYLOID FIBRILS within tissues.

Descriptor ID	D058225
MeSH Number(s)	C23.300.821
Concept/Terms	Plaque, Amyloid Plaque, Amyloid Amyloid Plaque Amyloid Plaques Plaques, Amyloid Amyloid Deposits Amyloid Deposit Deposit, Amyloid Deposits, Amyloid Senile Plaques Senile Plaques Plaque, Senile Plaques, Senile Senile Plaque Neuritic Plaques Neuritic Plaque Plaque, Neuritic Plaques, Neuritic

Below are MeSH descriptors whose meaning is more general than "Plaque, Amyloid".

Diseases [C]
Pathological Conditions, Signs and Symptoms [C23]
Pathological Conditions, Anatomical [C23.300]
Plaque, Amyloid [C23.300.821]

Below are MeSH descriptors whose meaning is more specific than "Plaque, Amyloid".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Plaque, Amyloid" by people in this website by year, and whether "Plaque, Amyloid" was a major or minor topic of these publications.

Bar chart showing 23 publications over 17 distinct years, with a maximum of 3 publications in 2008 and 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2000	0	1	1
2001	1	0	1
2003	1	1	2
2005	1	0	1
2006	0	1	1
2008	3	0	3
2009	1	0	1
2011	1	0	1
2012	0	1	1
2013	1	1	2
2014	1	2	3
2015	0	1	1
2016	0	1	1
2018	0	1	1
2019	1	0	1
2020	1	0	1
2022	0	1	1

Below are the most recent publications written about "Plaque, Amyloid" by people in Profiles.

Lin H, Dixon SG, Hu W, Hamlett ED, Jin J, Ergul A, Wang GY. p38 MAPK Is a Major Regulator of Amyloid Beta-Induced IL-6 Expression in Human Microglia. Mol Neurobiol. 2022 Sep; 59(9):5284-5298.

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Yu J, Zhu H, Taheri S, Mondy W, Perry S, Kirstein C, Kindy MS. Effects of GrandFusion Diet on Cognitive Impairment in Transgenic Mouse Model of Alzheimer's Disease. Nutrients. 2020 Dec 30; 13(1).

View in: PubMed
Tublin JM, Adelstein JM, Del Monte F, Combs CK, Wold LE. Getting to the Heart of Alzheimer Disease. Circ Res. 2019 01 04; 124(1):142-149.

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Nie X, Falangola MF, Ward R, McKinnon ET, Helpern JA, Nietert PJ, Jensen JH. Diffusion MRI detects longitudinal white matter changes in the 3xTg-AD mouse model of Alzheimer's disease. Magn Reson Imaging. 2019 04; 57:235-242.

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Chung YC, Kruyer A, Yao Y, Feierman E, Richards A, Strickland S, Norris EH. Hyperhomocysteinemia exacerbates Alzheimer's disease pathology by way of the ß-amyloid fibrinogen interaction. J Thromb Haemost. 2016 07; 14(7):1442-52.

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Baranello RJ, Bharani KL, Padmaraju V, Chopra N, Lahiri DK, Greig NH, Pappolla MA, Sambamurti K. Amyloid-beta protein clearance and degradation (ABCD) pathways and their role in Alzheimer's disease. Curr Alzheimer Res. 2015; 12(1):32-46.

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Greig NH, Sambamurti K, Lahiri DK, Becker RE. Amyloid-ß precursor protein synthesis inhibitors for Alzheimer's disease treatment. Ann Neurol. 2014 Oct; 76(4):629-30.

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Beecham GW, Hamilton K, Naj AC, Martin ER, Huentelman M, Myers AJ, Corneveaux JJ, Hardy J, Vonsattel JP, Younkin SG, Bennett DA, De Jager PL, Larson EB, Crane PK, Kamboh MI, Kofler JK, Mash DC, Duque L, Gilbert JR, Gwirtsman H, Buxbaum JD, Kramer P, Dickson DW, Farrer LA, Frosch MP, Ghetti B, Haines JL, Hyman BT, Kukull WA, Mayeux RP, Pericak-Vance MA, Schneider JA, Trojanowski JQ, Reiman EM, Schellenberg GD, Montine TJ. Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias. PLoS Genet. 2014 Sep; 10(9):e1004606.

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Hook G, Yu J, Toneff T, Kindy M, Hook V. Brain pyroglutamate amyloid-ß is produced by cathepsin B and is reduced by the cysteine protease inhibitor E64d, representing a potential Alzheimer's disease therapeutic. J Alzheimers Dis. 2014; 41(1):129-49.

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Sridharan A, Pehar M, Salamat MS, Pugh TD, Bendlin BB, Willette AA, Anderson RM, Kemnitz JW, Colman RJ, Weindruch RH, Puglielli L, Johnson SC. Calorie restriction attenuates astrogliosis but not amyloid plaque load in aged rhesus macaques: a preliminary quantitative imaging study. Brain Res. 2013 May 01; 1508:1-8.

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