Peroxisomal Multifunctional Protein-2

"Peroxisomal Multifunctional Protein-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A dimeric protein found in liver peroxisomes that plays an important role in FATTY ACID metabolism and steroid metabolism. The dimer is formed by cleavage of a single protein precursor and contains an enoyl-CoA hydratase-2 domain and a second domain that displays (S)-3-hydroxyacyl-CoA dehydrogenase and 17-beta-estradiol dehydrogenase activities. The enzyme is stereospecific with regards to arrangement of the substrate double bonds and position of the 3-hydroxy group of the reaction intermediate. It is complemented by PEROXISOMAL BIFUNCTIONAL ENZYME, which has the opposite reaction stereospecificity.

Descriptor ID	D064029
MeSH Number(s)	D08.811.520.241.300.275.500 D08.811.641.812 D08.811.682.047.436.375.640 D08.811.682.047.820.150.926
Concept/Terms	Peroxisomal Multifunctional Protein-2 Peroxisomal Multifunctional Protein-2 Multifunctional Protein-2, Peroxisomal Peroxisomal Multifunctional Protein 2 3-alpha,7-alpha,12-alpha-Trihydroxy-5-beta-Cholest-24-enoyl-CoA Hydratase Peroxisomal Multifunctional Enzyme Type 2 17-beta-Hydroxysteroid Dehydrogenase 4 17 beta Hydroxysteroid Dehydrogenase 4 4, 17-beta-Hydroxysteroid Dehydrogenase Dehydrogenase 4, 17-beta-Hydroxysteroid

Below are MeSH descriptors whose meaning is more general than "Peroxisomal Multifunctional Protein-2".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Lyases [D08.811.520]
Carbon-Oxygen Lyases [D08.811.520.241]
Hydro-Lyases [D08.811.520.241.300]
Enoyl-CoA Hydratase 2 [D08.811.520.241.300.275]
Peroxisomal Multifunctional Protein-2 [D08.811.520.241.300.275.500]
Multifunctional Enzymes [D08.811.641]
Peroxisomal Multifunctional Protein-2 [D08.811.641.812]
Oxidoreductases [D08.811.682]
Alcohol Oxidoreductases [D08.811.682.047]
Hydroxysteroid Dehydrogenases [D08.811.682.047.436]
17-Hydroxysteroid Dehydrogenases [D08.811.682.047.436.375]
Peroxisomal Multifunctional Protein-2 [D08.811.682.047.436.375.640]
NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases [D08.811.682.047.820]
3-Hydroxyacyl CoA Dehydrogenases [D08.811.682.047.820.150]
Peroxisomal Multifunctional Protein-2 [D08.811.682.047.820.150.926]

Below are MeSH descriptors whose meaning is related to "Peroxisomal Multifunctional Protein-2".

Below are MeSH descriptors whose meaning is more specific than "Peroxisomal Multifunctional Protein-2".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Peroxisomal Multifunctional Protein-2" by people in this website by year, and whether "Peroxisomal Multifunctional Protein-2" was a major or minor topic of these publications.

To see the data from this visualization as text, click here.