Transcriptional Regulator ERG
"Transcriptional Regulator ERG" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A trans-activator and member of the erythroblast transformation-specific family of transcriptions factors that contain a characteristic ETS MOTIF. It is required for PLATELET CELL ADHESION to the subendothelium and associates with CHIMERIC ONCOGENE PROTEINS in PROSTATE CANCER; EWING'S SARCOMA; and ACUTE MYELOID LEUKEMIA.
| Descriptor ID |
D000071230
|
| MeSH Number(s) |
D12.776.260.755.100 D12.776.930.900.625
|
| Concept/Terms |
Transcriptional Regulator ERG- Transcriptional Regulator ERG
- Transforming Protein ERG
- V-Ets Avian Erythroblastosis Virus E26 Oncogene Homolog Protein
- V Ets Avian Erythroblastosis Virus E26 Oncogene Homolog Protein
- V-Ets Avian Erythroblastosis Virus E26 Oncogene Related Protein
- V Ets Avian Erythroblastosis Virus E26 Oncogene Related Protein
|
Below are MeSH descriptors whose meaning is more general than "Transcriptional Regulator ERG".
Below are MeSH descriptors whose meaning is more specific than "Transcriptional Regulator ERG".
This graph shows the total number of publications written about "Transcriptional Regulator ERG" by people in this website by year, and whether "Transcriptional Regulator ERG" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Transcriptional Regulator ERG" by people in Profiles.
-
Novel high-risk acute myeloid leukemia subgroup with ERG amplification and Biallelic loss of TP53. Cancer Genet. 2023 04; 272-273:23-28.
-
SPOP Promotes Ubiquitination and Degradation of the ERG Oncoprotein to Suppress Prostate Cancer Progression. Mol Cell. 2015 Sep 17; 59(6):917-30.
-
Dual requirement for the ETS transcription factors Fli-1 and Erg in hematopoietic stem cells and the megakaryocyte lineage. Proc Natl Acad Sci U S A. 2009 Aug 18; 106(33):13814-9.
-
Clinical, genetic, and biophysical characterization of a homozygous HERG mutation causing severe neonatal long QT syndrome. Pediatr Res. 2003 May; 53(5):744-8.