"Anoctamin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An anoctamin chloride channel expressed at high levels in the liver, skeletal muscle, and gastrointestinal muscles that functions in transepithelial anion transport and smooth muscle contraction. It is essential for the function of the INTERSTITIAL CELLS OF CAJAL and plays a major role in chloride conduction by airway epithelial cells and in tracheal cartilage development.
| Descriptor ID |
D000075369
|
| MeSH Number(s) |
D12.776.157.530.400.175.032.500 D12.776.543.550.450.175.032.500 D12.776.543.585.400.175.032.500
|
| Concept/Terms |
Anoctamin-1- Anoctamin-1
- Anoctamin 1
- Transmembrane Protein 16A
- TMEM16A Protein
|
Below are MeSH descriptors whose meaning is more general than "Anoctamin-1".
Below are MeSH descriptors whose meaning is more specific than "Anoctamin-1".
This graph shows the total number of publications written about "Anoctamin-1" by people in this website by year, and whether "Anoctamin-1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Anoctamin-1" by people in Profiles.
-
Signaling through the interleukin-4 and interleukin-13 receptor complexes regulates cholangiocyte TMEM16A expression and biliary secretion. Am J Physiol Gastrointest Liver Physiol. 2020 04 01; 318(4):G763-G771.
-
PKCa regulates TMEM16A-mediated Cl? secretion in human biliary cells. Am J Physiol Gastrointest Liver Physiol. 2016 Jan 01; 310(1):G34-42.
-
Identification and functional characterization of TMEM16A, a Ca2+-activated Cl- channel activated by extracellular nucleotides, in biliary epithelium. J Biol Chem. 2011 Jan 07; 286(1):766-76.