"Receptors, Somatotropin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface proteins that bind GROWTH HORMONE with high affinity and trigger intracellular changes influencing the behavior of cells. Activation of growth hormone receptors regulates amino acid transport through cell membranes, RNA translation to protein, DNA transcription, and protein and amino acid catabolism in many cell types. Many of these effects are mediated indirectly through stimulation of the release of somatomedins.
| Descriptor ID |
D011986
|
| MeSH Number(s) |
D12.776.543.750.750.555.770 D12.776.543.750.750.660.750
|
| Concept/Terms |
Receptors, Somatotropin- Receptors, Somatotropin
- Receptor, Growth Hormone
- Somatotropin Receptors
- Receptors, Growth Hormone
- Somatotropin Receptor
- Growth Hormone Receptor
- Hormone Receptor, Growth
- Growth Hormone Receptors
- Hormone Receptors, Growth
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Somatotropin".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Somatotropin".
This graph shows the total number of publications written about "Receptors, Somatotropin" by people in this website by year, and whether "Receptors, Somatotropin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1995 | 1 | 0 | 1 |
| 1996 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Somatotropin" by people in Profiles.
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Hascup KN, Lynn MK, Fitzgerald PJ, Randall S, Kopchick JJ, Boger HA, Bartke A, Hascup ER. Enhanced Cognition and Hypoglutamatergic Signaling in a Growth Hormone Receptor Knockout Mouse Model of Successful Aging. J Gerontol A Biol Sci Med Sci. 2017 03 01; 72(3):329-337.
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Yi W, Kim SO, Jiang J, Park SH, Kraft AS, Waxman DJ, Frank SJ. Growth hormone receptor cytoplasmic domain differentially promotes tyrosine phosphorylation of signal transducers and activators of transcription 5b and 3 by activated JAK2 kinase. Mol Endocrinol. 1996 Nov; 10(11):1425-43.
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Frank SJ, Yi W, Zhao Y, Goldsmith JF, Gilliland G, Jiang J, Sakai I, Kraft AS. Regions of the JAK2 tyrosine kinase required for coupling to the growth hormone receptor. J Biol Chem. 1995 Jun 16; 270(24):14776-85.
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Frank SJ, Gilliland G, Kraft AS, Arnold CS. Interaction of the growth hormone receptor cytoplasmic domain with the JAK2 tyrosine kinase. Endocrinology. 1994 Nov; 135(5):2228-39.