Heymann Nephritis Antigenic Complex
"Heymann Nephritis Antigenic Complex" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A complex of antigenic proteins obtained from the brush border of kidney tubules. It contains two principal components LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-2 and LDL-RECEPTOR RELATED PROTEIN-ASSOCIATED PROTEIN. The name of this complex is derived from researcher, Dr. Walter Heymann, who developed an experimental model of membranous glomerulonephritis (GLOMERULONEPHRITIS) by injecting this antigenic complex into rats to induce an autoimmune response.
| Descriptor ID |
D026541
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| MeSH Number(s) |
D23.050.422.500
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| Concept/Terms |
Heymann Nephritis Antigenic Complex- Heymann Nephritis Antigenic Complex
- Nephritis Antigen, Heyman
- Heyman Nephritis Antigen
- Receptor-Associated Protein, Heymann Nephritis
- Receptor Associated Protein, Heymann Nephritis
- Heymann's Antigen
- Heymann Antigen
- Heymanns Antigen
- Nephritogenic Antigen
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Below are MeSH descriptors whose meaning is more general than "Heymann Nephritis Antigenic Complex".
Below are MeSH descriptors whose meaning is more specific than "Heymann Nephritis Antigenic Complex".
This graph shows the total number of publications written about "Heymann Nephritis Antigenic Complex" by people in this website by year, and whether "Heymann Nephritis Antigenic Complex" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
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Below are the most recent publications written about "Heymann Nephritis Antigenic Complex" by people in Profiles.
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Megalin acts in concert with cubilin to mediate endocytosis of high density lipoproteins. J Biol Chem. 2000 Apr 21; 275(16):12003-8.
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Interaction of apolipoprotein J-amyloid beta-peptide complex with low density lipoprotein receptor-related protein-2/megalin. A mechanism to prevent pathological accumulation of amyloid beta-peptide. J Biol Chem. 1997 Jul 25; 272(30):18644-9.
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Glycoprotein 330/low density lipoprotein receptor-related protein-2 mediates endocytosis of low density lipoproteins via interaction with apolipoprotein B100. J Biol Chem. 1995 Aug 18; 270(33):19417-21.
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An overview of the structure and function of glycoprotein 330, a receptor related to the alpha 2-macroglobulin receptor. Ann N Y Acad Sci. 1994 Sep 10; 737:114-23.
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Chromosomal localization of human genes for the LDL receptor family member glycoprotein 330 (LRP2) and its associated protein RAP (LRPAP1). Genomics. 1994 Jul 01; 22(1):88-93.
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Primary structure of alpha 2-macroglobulin receptor-associated protein. Human homologue of a Heymann nephritis antigen. J Biol Chem. 1991 Jul 15; 266(20):13364-9.