Omeprazole

"Omeprazole" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.

Descriptor ID	D009853
MeSH Number(s)	D02.886.640.074.500 D03.383.725.024.500 D03.633.100.103.034.500
Concept/Terms	Omeprazole Omeprazole Prilosec Prilosec Omeprazole Sodium Omeprazole Sodium Sodium, Omeprazole H 168-68 H 168-68 H 168 68 H 16868 Omeprazole Magnesium Omeprazole Magnesium Magnesium, Omeprazole

Below are MeSH descriptors whose meaning is more general than "Omeprazole".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Sulfur Compounds [D02.886]
Sulfoxides [D02.886.640]
2-Pyridinylmethylsulfinylbenzimidazoles [D02.886.640.074]
Omeprazole [D02.886.640.074.500]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, 1-Ring [D03.383]
Pyridines [D03.383.725]
2-Pyridinylmethylsulfinylbenzimidazoles [D03.383.725.024]
Omeprazole [D03.383.725.024.500]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
Benzimidazoles [D03.633.100.103]
2-Pyridinylmethylsulfinylbenzimidazoles [D03.633.100.103.034]
Omeprazole [D03.633.100.103.034.500]

Below are MeSH descriptors whose meaning is related to "Omeprazole".

Below are MeSH descriptors whose meaning is more specific than "Omeprazole".

Omeprazole
Esomeprazole

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Omeprazole" by people in this website by year, and whether "Omeprazole" was a major or minor topic of these publications.

Bar chart showing 48 publications over 16 distinct years, with a maximum of 7 publications in 1996

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	1	1	2
1995	4	0	4
1996	5	2	7
1997	4	1	5
1998	5	0	5
1999	5	1	6
2000	0	2	2
2001	4	0	4
2002	2	1	3
2004	1	0	1
2005	3	1	4
2006	1	0	1
2008	0	1	1
2015	1	0	1
2016	0	1	1
2019	1	0	1

Below are the most recent publications written about "Omeprazole" by people in Profiles.

Spechler SJ, Hunter JG, Jones KM, Lee R, Smith BR, Mashimo H, Sanchez VM, Dunbar KB, Pham TH, Murthy UK, Kim T, Jackson CS, Wallen JM, von Rosenvinge EC, Pearl JP, Laine L, Kim AW, Kaz AM, Tatum RP, Gellad ZF, Lagoo-Deenadayalan S, Rubenstein JH, Ghaferi AA, Lo WK, Fernando RS, Chan BS, Paski SC, Provenzale D, Castell DO, Lieberman D, Souza RF, Chey WD, Warren SR, Davis-Karim A, Melton SD, Genta RM, Serpi T, Biswas K, Huang GD. Randomized Trial of Medical versus Surgical Treatment for Refractory Heartburn. N Engl J Med. 2019 10 17; 381(16):1513-1523.

View in: PubMed
Dunbar KB, Agoston AT, Odze RD, Huo X, Pham TH, Cipher DJ, Castell DO, Genta RM, Souza RF, Spechler SJ. Association of Acute Gastroesophageal Reflux Disease With Esophageal Histologic Changes. JAMA. 2016 May 17; 315(19):2104-12.

View in: PubMed
Abdul-Hussein M, Freeman J, Castell D. Concomitant Administration of a Histamine2 Receptor Antagonist and Proton Pump Inhibitor Enhances Gastric Acid Suppression. Pharmacotherapy. 2015 Dec; 35(12):1124-9.

View in: PubMed
Barada K, Karrowni W, Abdallah M, Shamseddeen W, Sharara AI, Dakik HA. Upper gastrointestinal bleeding in patients with acute coronary syndromes: clinical predictors and prophylactic role of proton pump inhibitors. J Clin Gastroenterol. 2008 Apr; 42(4):368-72.

View in: PubMed
Wo JM, Koopman J, Harrell SP, Parker K, Winstead W, Lentsch E. Double-blind, placebo-controlled trial with single-dose pantoprazole for laryngopharyngeal reflux. Am J Gastroenterol. 2006 Sep; 101(9):1972-8; quiz 2169.

View in: PubMed
Kaplan GG, Bates D, McDonald D, Panaccione R, Romagnuolo J. Inappropriate use of intravenous pantoprazole: extent of the problem and successful solutions. Clin Gastroenterol Hepatol. 2005 Dec; 3(12):1207-14.

View in: PubMed
Castell D. Review of immediate-release omeprazole for the treatment of gastric acid-related disorders. Expert Opin Pharmacother. 2005 Nov; 6(14):2501-10.

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Halstead LA. Extraesophageal manifestations of GERD: diagnosis and therapy. Drugs Today (Barc). 2005 Jul; 41 Suppl B:19-26.

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Castell D, Bagin R, Goldlust B, Major J, Hepburn B. Comparison of the effects of immediate-release omeprazole powder for oral suspension and pantoprazole delayed-release tablets on nocturnal acid breakthrough in patients with symptomatic gastro-oesophageal reflux disease. Aliment Pharmacol Ther. 2005 Jun 15; 21(12):1467-74.

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Tutuian R, Castell DO, Xue S, Katz PO. The acidity index: a simple approach to the measurement of gastric acidity. Aliment Pharmacol Ther. 2004 Feb 15; 19(4):443-8.

View in: PubMed

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