"Ouabain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like DIGITALIS. It is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-EXCHANGING ATPASE.
| Descriptor ID |
D010042
|
| MeSH Number(s) |
D04.210.500.155.580.130.750.600 D09.408.180.810.600
|
| Concept/Terms |
Ouabain- Ouabain
- G-Strophanthin
- G Strophanthin
- Acocantherin
- Acolongifloroside K
|
Below are MeSH descriptors whose meaning is more general than "Ouabain".
Below are MeSH descriptors whose meaning is more specific than "Ouabain".
This graph shows the total number of publications written about "Ouabain" by people in this website by year, and whether "Ouabain" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2011 | 0 | 2 | 2 |
| 2013 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ouabain" by people in Profiles.
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Contributions of Mouse and Human Hematopoietic Cells to Remodeling of the Adult Auditory Nerve After Neuron Loss. Mol Ther. 2016 Nov; 24(11):2000-2011.
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Ouabain-induced cochlear nerve degeneration: synaptic loss and plasticity in a mouse model of auditory neuropathy. J Assoc Res Otolaryngol. 2014 Feb; 15(1):31-43.
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Role of stromal cell-derived factor-1 expression in the injured mouse auditory nerve. Otolaryngol Head Neck Surg. 2011 Dec; 145(6):1007-15.
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Sox2 up-regulation and glial cell proliferation following degeneration of spiral ganglion neurons in the adult mouse inner ear. J Assoc Res Otolaryngol. 2011 Apr; 12(2):151-71.
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Transplantation of mouse embryonic stem cells into the cochlea of an auditory-neuropathy animal model: effects of timing after injury. J Assoc Res Otolaryngol. 2008 Jun; 9(2):225-40.
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Ouabain induces apoptotic cell death in type I spiral ganglion neurons, but not type II neurons. J Assoc Res Otolaryngol. 2005 Mar; 6(1):63-74.
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Novel regulation of cell [Na(+)] in macula densa cells: apical Na(+) recycling by H-K-ATPase. Am J Physiol Renal Physiol. 2002 Feb; 282(2):F324-9.
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Variation in the electrical properties of cultured human proximal tubule cells. In Vitro Cell Dev Biol Anim. 1993 May; 29A(5):371-8.
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Na,K-ATPase in resting and stimulated submandibular salivary glands in cats, studied by means of ouabain-sensitive, K(+)-dependent p-nitrophenylphosphatase activity. Arch Oral Biol. 1992 Sep; 37(9):711-6.
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Myocardial Na+,K(+)-ATPase in tachycardia induced cardiomyopathy. J Mol Cell Cardiol. 1992 Mar; 24(3):277-94.