"Doxepin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
| Descriptor ID |
D004316
|
| MeSH Number(s) |
D02.355.291.852.500 D03.633.300.382.393
|
| Concept/Terms |
Doxepin Hydrochloride- Doxepin Hydrochloride
- Hydrochloride, Doxepin
- Doxepin Hydrochloride, Cis-Trans Isomer Mixture (approximately 1:5)
|
Below are MeSH descriptors whose meaning is more general than "Doxepin".
Below are MeSH descriptors whose meaning is more specific than "Doxepin".
This graph shows the total number of publications written about "Doxepin" by people in this website by year, and whether "Doxepin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Doxepin" by people in Profiles.
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Insomnia: Pharmacologic Therapy. Am Fam Physician. 2017 Jul 01; 96(1):29-35.
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Doxepin rinse versus placebo in the treatment of acute oral mucositis pain in patients receiving head and neck radiotherapy with or without chemotherapy: a phase III, randomized, double-blind trial (NCCTG-N09C6 [Alliance]). J Clin Oncol. 2014 May 20; 32(15):1571-7.
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Effects of prenatal exposure to tricyclic antidepressants on adrenergic responses in progeny. Dev Pharmacol Ther. 1985; 8(1):17-33.
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A clinical report of thymoleptic-responsive atypical paranoid psychoses. Am J Psychiatry. 1983 Sep; 140(9):1187-90.